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Yisheng Biotechnology (Shanghai) Co., Ltd

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    3rd Floor, No. 1, Lane 166, Tianxiong Road, Pudong New Area, Shanghai

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Raffinose marshmallow

NegotiableUpdate on 05/06
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Overview

Raffinose exerts orally effective anti-inflammatory, antioxidant, and immunomodulatory effects by regulating gut microbiota composition, inhibiting the TLR4-MyD88-NF - κ B inflammatory pathway, and activating the Nrf2 antioxidant pathway.

Product Details

Product Introduction

Raffinose exerts orally effective anti-inflammatory, antioxidant, and immunomodulatory effects by regulating gut microbiota composition, inhibiting the TLR4-MyD88-NF - κ B inflammatory pathway, and activating the Nrf2 antioxidant pathway.

Product properties
Nature name
Nature Details
CAS Number (CAS NO.)
512-69-6
English Synonym
Melitose; Melitose (Standard)
Chinese Name
Cottonseed sugar; Cottonseed sugar (standard);
Target
NF-κB
Research Field
NF-κB
Pathway
NF-κB
Molecular formula (Formula)
C18H32O16
Molecular Weight
504.44
Appearance
Solid powder
Purity
≥ 98%, analytical standard grade
Solubility
Soluble in water: ≥ 50 mg/mL
Structure
Raffinose 棉子糖
Cell experiment (in vitro experiment)
After treatment with 0-200 mM Raffinose for 48 hours, the autophagy activity of HaCaT cells was significantly enhanced, while the release of lactate dehydrogenase (LDH) was reduced, effectively alleviating UVB radiation-induced cell damage. [1]
Animal experiments (in vivo experiments)
Daily oral administration of 100-400 mg/kg Raffinose for 21 days can significantly improve the pathological symptoms of DSS induced colitis in mice by regulating gut microbiota composition, inhibiting the TLR4-MyD88-NF - κ B inflammatory pathway, and alleviating oxidative stress, confirming its multi-target regulatory mechanism of intestinal immune homeostasis. [2]
Product Features

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Storage conditions

Store at 2-8 ℃ away from light, with a shelf life of 3 years.