- Phone
-
Address
No. 12 Shuangyuan Road, Beichen District, Tianjin City
Product Categories
Youyi Quan (Tianjin) Biotechnology Co., Ltd
Protein freeze dryer
NegotiableUpdate on 05/07
- Model
- Nature of the Manufacturer
- Producers
- Product Category
- Place of Origin
Overview
The bacterial strains stored by freeze-drying method in protein freeze-drying machine can have a storage period of several years to ten years. In order to avoid errors after many years, special attention should be paid to the purity of the bacterial strains used, that is, they cannot be contaminated by miscellaneous bacteria. Therefore, in the selection of freeze-drying equipment, it is necessary to meet the requirements of GMP in order to achieve excellent freeze-drying quality of bacterial strains.
Product Details
LYO seriesMain functions of protein freeze dryer:
★ Pre freezing function of the board layer.
★ It can be stored after drying by filling with nitrogen or inert gas.
★ Freeze drying automatic control system: programmable control from freeze-drying to defrosting.
★ Board layer: The welding process used ensures no leakage of the board layer (with a three-year warranty).
★ Freeze drying endpoint testing system: It can automatically perform freeze drying endpoint testing after the analytical drying stage is completed to ensure that the moisture content of the substance meets the standard requirements.
★ Vacuum regulation system: Adjust the vacuum degree during sublimation and analytical drying processes to avoid problems such as foaming of special substances, bottle blowing, and accelerated freeze-drying efficiency.
★ Pulse Backfilling System: Three backfilling modes can be selected: slow, medium, and fast, avoiding the problem of effective substances being blown away due to inflation of granular and flocculent materials after freeze-drying.
★ Adopting a large-sized industrial touch screen, it has good human-computer interaction, is simple and easy to understand, and can be operated easily without the need for instructions.
★ Monitoring system: Real time monitoring of system temperature and vacuum degree, with a collection frequency of up to 50ms/time.
★ Freeze drying process formula storage function: can store 300 sets of fixed or user-defined freeze drying process formulas.
★ PC remote monitoring system: It can remotely monitor the operation status of equipment, with a maximum monitoring distance of 1.5KM.
★ Calibration function: Temperature and vacuum calibration can be performed to ensure the accuracy of long-term measurement values.
★ Freeze drying curve query function (can query temperature and vacuum degree curves, convenient for process optimization and freeze-drying effect verification).
Selection Guide:
SIP type is suitable for use in the pharmaceutical industry.
CIP type is suitable for use in the field of biotechnology.
Ordinary type suitable for use in industrial, food and other fields
LYO series standard seriesProtein freeze dryerTechnical parameters
| model | Board area（㎡ ) | Number of layers | Board size (mm) | The average thickness of each layer is one degree（℃) | Capture water volume | Bottled quantity | Plate layer temperature（℃) | Cold trap temperature（℃) | power |
| (L) | （∮22) | (KW) | |||||||
| LYO-2 | 2.1 | 4+1 | 600*900 | ±1.0 | 40 | 4200 | -135 | <-75 | 12 |
| LYO-3 | 3.2 | 6+1 | 600*900 | 60 | 6300 | 21 | |||
| LYO-5 | 4.8 | 6+1 | 900*900 | 100 | 9450 | 24 | |||
| LYO-7 | 7.5 | 7+1 | 900*1200 | 150 | 15750 | 44 | |||
| LYO-10 | 9.7 | 9+1 | 900*1200 | 200 | 19950 | 58 | |||
| LYO-13 | 12.9 | 9+1 | 1200*1200 | 260 | 26250 | 67 | |||
| LYO-15 | 16.1 | 9+1 | 1200*1490 | 320 | 33600 | 75 | |||
| LYO-20 | 19.6 | 11+1 | 1200*1490 | 400 | 42900 | 104 | |||
| LYO-25 | 25 | 14+1 | 1200*1490 | 500 | 52500 | 125 | |||
| LYO-30 | 31.5 | 14+1 | 1490*1490 | 600 | 60900 | 134 | |||
| LYO-40 | 42 | 14+1 | 1490*1990 | 800 | 84000 | 174 | |||
| LYO-50 | 51 | 17+1 | 1490*1990 | 1000 | 105000 | 210 |
Features:
★ Box:
The box design is carried out in accordance with GB150-2011/PED/ASME standards and meets the requirements of FDA and GMP standards. The interior of the box adopts a large rounded corner design, the surface is polished with a mirror finish, and the bottom of the box adopts an inclined angle design, which is more in line with CIP and SIP drainage requirements. The box can withstand a full range of positive and negative pressures from 0.15Mpa to 0.5Pa.
★ Board layer:
The welding process used to manufacture the board layer.
1. Internal welding.
2. TIG welding.
3. Track welding technology
★ Cold trap:
The cold trap adopts mirror polishing technology, with a bright and smooth surface. Optimized design of water vapor channels to reduce molecular surge resistance and improve water capture efficiency.
★ Refrigeration system
The refrigeration compressor used ensures the safety and stability of the refrigeration system.
★ Vacuum system
The vacuum pipeline adopts automatic track welding to ensure firm and beautiful welding. Vacuum leak detection is carried out using a helium mass spectrometer to ensure that the vacuum system meets high vacuum requirements.
★ CIP system
The valves and pneumatic actuators of the in-situ cleaning system are all imported components to ensure stable, safe and reliable operation. The pipeline of the in-situ cleaning system adopts automatic track welding to ensure that the welding is firm and beautiful. The CIP system pipeline vacuum leak detection is carried out using a helium mass spectrometer to ensure that the vacuum system meets high vacuum requirements. After cleaning, residual moisture is removed using a German imported water ring pump with high pumping speed.
★ SIP system
Adopting pulsating pre vacuum steam sterilization method, equipped with Fo value display and recording, it has complete safety interlock and interlocking functions, and the box comes with cooling function. Triple overpressure protection ensures safety. The design of the high-pressure pressure vessel for the box body, and all components during the manufacturing process are inspected and tested by industrial X-ray machines to ensure overall stability and high pressure resistance. The valves of the in-situ disinfection system are all imported components with a temperature resistance of over 350 ℃. Pneumatic actuators are all made of imported components to ensure stable, safe and reliable operation. The pipeline of the in-situ disinfection system adopts automatic track welding to ensure that the welding is firm and beautiful. The SIP system pipeline vacuum leak detection is carried out using a helium mass spectrometer to ensure that the vacuum system meets high vacuum requirements. After disinfection, residual moisture is removed using a German imported water ring pump with high pumping speed. The disinfection temperature can reach 150 ℃.
★ Process control system
Meet the non modifiable requirements for electronic records and electronic signatures in FDA 21CFR PART11. Accurate control, repeatable and reproducible.
★ Plate heat exchanger
The plate heat exchanger used has high heat transfer efficiency.
Safety:
★ Independent overcurrent protection for each facility
★ Independent overload protection for each facility
★ Conditions are met to allow various facilities to operate
★ Heating over temperature protection
★ Vacuum protection during product freeze-drying process
★ Vacuum pump protection
★ System logic interlock
★ Compliant with GMP standards
Service
★ 1-year warranty
★ Installation and operation training once
★ Freeze drying process training once
★ Sample process optimization once (sending samples)
★ Lifetime maintenance of the product (with corresponding fees charged)
★ Product upgrade service (charging corresponding fees)
★ Transportation (excluding unloading, unpacking, transportation to designated locations, and equipment isolation for water, electricity, and pipeline construction)
See: Equipment Configuration Details
Probiotic freeze-dryingMachine features:
★ Box:
The box design is carried out in accordance with GB150-2011/PED/ASME standards and meets the requirements of FDA and GMP standards. The interior of the box adopts a large rounded corner design, the surface is polished with a mirror finish, and the bottom of the box adopts an inclined angle design, which is more in line with CIP and SIP drainage requirements. The box can withstand a full range of positive and negative pressures from 0.15Mpa to 0.5Pa.
★ Board layer:
The welding process used to manufacture the board layer.
1. Internal welding.
2. TIG welding.
3. Track welding technology
★ Cold trap:
The cold trap adopts mirror polishing technology, with a bright and smooth surface. Optimized design of water vapor channels to reduce molecular surge resistance and improve water capture efficiency.
★ Refrigeration system
The refrigeration compressor used ensures the safety and stability of the refrigeration system.
★ Vacuum system
The vacuum pipeline adopts automatic track welding to ensure firm and beautiful welding. Vacuum leak detection is carried out using a helium mass spectrometer to ensure that the vacuum system meets high vacuum requirements.
★ CIP system
The valves and pneumatic actuators of the in-situ cleaning system are all imported components to ensure stable, safe and reliable operation. The pipeline of the in-situ cleaning system adopts automatic track welding to ensure that the welding is firm and beautiful. The CIP system pipeline vacuum leak detection is carried out using a helium mass spectrometer to ensure that the vacuum system meets high vacuum requirements. After cleaning, residual moisture is removed using a German imported water ring pump with high pumping speed.
★ SIP system
Adopting pulsating pre vacuum steam sterilization method, equipped with Fo value display and recording, it has complete safety interlock and interlocking functions, and the box comes with cooling function. Triple overpressure protection ensures safety. The design of the high-pressure pressure vessel for the box body, and all components during the manufacturing process are inspected and tested by industrial X-ray machines to ensure overall stability and high pressure resistance. The valves of the in-situ disinfection system are all imported components with a temperature resistance of over 350 ℃. Pneumatic actuators are all made of imported components to ensure stable, safe and reliable operation. The pipeline of the in-situ disinfection system adopts automatic track welding to ensure that the welding is firm and beautiful. The SIP system pipeline vacuum leak detection is carried out using a helium mass spectrometer to ensure that the vacuum system meets high vacuum requirements. After disinfection, residual moisture is removed using a German imported water ring pump with high pumping speed. The disinfection temperature can reach 150 ℃.
★ Process control system
Meet the non modifiable requirements for electronic records and electronic signatures in FDA 21CFR PART11. Accurate control, repeatable and reproducible.
★ Plate heat exchanger
The plate heat exchanger used has high heat transfer efficiency.
Safety:
★ Independent overcurrent protection for each facility
★ Independent overload protection for each facility
★ Conditions are met to allow various facilities to operate
★ Heating over temperature protection
★ Vacuum protection during product freeze-drying process
★ Vacuum pump protection
★ System logic interlock
★ Compliant with GMP standards
Service
★ 1-year warranty
★ Installation and operation training once
★ Freeze drying process training once
★ Sample process optimization once (sending samples)
★ Lifetime maintenance of the product (with corresponding fees charged)
★ Product upgrade service (charging corresponding fees)
★ Transportation (excluding unloading, unpacking, transportation to designated locations, and equipment isolation for water, electricity, and pipeline construction)
Similar Product Recommend