PreciseInhale Rodent Tracheal Exposure Module

PreciseInhale Rodent Tracheal Exposure ModuleProvided lung specific intratracheal aerosol testing for one animal at a time bypassing the nasal airway, in vivo (In Vivo) studies were conducted on rats with endotracheal intubation exposed to aerosols, including plasma and lung pharmacokinetic (PK) data, Cmax and t1/2, as well as substances retained in the lungs.

This module needs to be compatible withPreciseInhale gasSol generatorCombined with usage, as shown in the figure below, each module and host are produced by Inhalation Sciences Sweden AB (ISAB), an innovative instrument listed company headquartered in Sweden that provides analytical instruments and research services. Its products are mainly used for aerosol and inhalation formulation research.

PreciseInhale Rodent Tracheal Exposure ModuleThe advantages and main performance are as follows:

• The precise exposure method of one animal at a time significantly reduced the standard deviation of lung deposition dose, in line with the 3R principle

• With the precise administration of PreciseInhale aerosol generator unit,Ensure that the powerful energy released during aerosol atomization does not harm the delicate lungs of rodents. This more precise and controllable administration reduces animal stress and provides finer and more uniform lung distribution for aerosols.

• Through endotracheal intubation, bypass the nasal airway to achieve lung specific exposure

• Extremely low sample size

• Monitor aerosol concentration and animal respiratory patterns throughout the entire process
  

• Provide a complete experimental report, including plasma and lung pharmacokinetic (PK) data, Cmax and t1/2, as well as substances retained in the lungs