Pharmaceutical grade hydroxypropyl cellulose disintegrant filler with full registration qualifications

NegotiableUpdate on 05/06

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Nature of the Manufacturer: Producers

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Overview

Xi'an Jinxiang Pharmaceutical Auxiliary Materials Co., Ltd. has full qualifications for the registration of pharmaceutical grade hydroxypropyl cellulose disintegrant fillers. Its business covers the supply of raw and auxiliary materials in the manufacturing and production processes of the pharmaceutical industry, healthcare manufacturing industry, domestic key pharmaceutical research and development institutions, research centers of pharmaceutical colleges and universities, preparation centers of traditional Chinese and Western medicine characteristic hospitals, various skin specialty hospitals, and other fields. Committed to providing more high-quality sources of goods for domestic customers in the fields of medicine, disinfection, food, cosmetics, chemicals, agriculture, etc. We warmly welcome customers from all fields across the country to communicate and negotiate cooperation.

Product Details

Pharmaceutical grade hydroxypropyl cellulose disintegrant filler with full registration qualifications

Hydroxypropyl cellulose

[9004-64-2]

This product is a partial replacement2-Hydroxypropyl ether cellulose. Calculated as dry product, containing hydroxypropyl oxide（-OCH2CHOHCH3）Should be53.4%～80.5%.

【 Appearance 】 This product is a white to off white powder or granule.

【 Identification 】（1）Take this product approximately1gHeating water100mlStir to form a slurry like liquid, cool in an ice bath to form a viscous liquid, and take2mlPlace it in a test tube and slowly add along the tube wall0.035%Sulfuric acid solution of anthrone1mlPlace it5Minutes, a blue-green ring appears at the interface between the two liquids.

（2）Take identification（1）Pour an appropriate amount of viscous liquid onto a glass plate and wait for the water to evaporate to form a thin film.

（3）Take identification（1）Add an appropriate amount of viscous liquid under the item, heat and stir in a water bath until the solution temperature reaches40When the temperature is above ℃, the solution becomes turbid or forms a flocculent precipitate. After cooling, the solution becomes clear again.

Dry weight loss: Take this product, in105Dry at ℃4Hours, weight loss must not exceed5%(General rules)0831）.

Silicon dioxide (if labeled as containing silicon dioxide and tested according to the method under the ignition residue item, the residue amount exceeds0.2%Time measurement) Take this product1.0gPlace it in a platinum crucible1000Ignite at ℃ until constant weight. Wet the residue with water and drip itsour10mlSteam dry on a water bath, let cool, and continue adding10mlWith sulfuric acid0.5mlEvaporate on a water bath until almost dry, then transfer to an electric furnace and slowly heat until the acid vapor is removed1000Ignite at ℃ to constant weight, cool down, accurately weigh, and the difference between the weight of silica and the constant weight residue is the weight of silica. Calculated as a dry product, it should not exceed0.6%.

Burning residue: Take this product1.0gInspect in accordance with the law (General Principles)0841）The remaining residue shall not be passed over0.8%.

The residue left under the ignition residue of heavy metals shall be inspected in accordance with the law (General Rules)0821The second method states that the content of heavy metals shall not exceed 10 parts per million.

Arsenic salt is taken from this product1.0gAdd calcium hydroxide1.0gMix well, add a small amount of water, stir evenly, dry, first burn on low heat to carbonize, and then500～600Ignite at ℃ to achieve complete ashing, cool, and add hydrochloric acid8mlWith water23mlInspect in accordance with the law (General Principles)0822The first law should comply with the regulations（0.0002%）.

Hydroxypropyl group determination method based on methoxy, ethoxy, and hydroxypropyl groups (general rules)0712）Measurement. If using the second method (capacity method), take approximately0.1gAccurately weighed and measured according to the law, it is obtained.

[Category] Disintegrating agents and fillers, etc.

【 Storage 】 Keep tightly sealed and stored in a dry place.

Pharmaceutical grade hydroxypropyl cellulose disintegrant filler with full registration qualifications