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AOPUTE Technology (Shanghai) Co., Ltd

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Room 602, Building A, Minggu Science and Technology Park, No. 7001 Zhongchun Road, Minhang District, Shanghai

Nano particle size and Zeta potential analyzer

NegotiableUpdate on 05/07

Model

Nature of the Manufacturer: Producers

Product Category

Place of Origin

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Overview

The 9x9 series nanoparticle size and Zeta potential analyzer uses a high-speed digital correlator as its core device, measuring particle size using dynamic light scattering technology, Zeta potential using phase analysis light scattering technology, and molecular weight using static light scattering technology. The measurement results are accurate and reliable, making it a reliable choice for measuring nanoparticle size and Zeta potential.

Product Details

Technical features:

1. All fiber optical path: By using all fiber optical path instead of discrete optical path, the reference light and scattered light signals are no longer affected by dust and stray light interference, significantly improving the signal-to-noise ratio and anti-interference ability.

2. Backscattered light path: By using a backscattered light path to reduce the scattering path length and weaken multiple scattered light, the particle size of high concentration samples can be measured.

3. Large dynamic range high-speed digital correlator: Using a photon correlator with high-speed and low-speed channels, it effectively solves the contradiction between hardware resources and channel quantity, and obtains real-time correlation functions with large dynamic range and stable baseline.

4. Data filtering function: Introducing the method of quantile detection for outliers, identifying scattered light data affected by dust interference, and removing outliers to improve the accuracy of granularity measurement results.

5. Multi angle data inversion: Collecting scattered light intensity from multiple different scattering angles can obtain more particle size information, and combining multiple autocorrelation functions into one data analysis can improve the accuracy of particle size distribution.

6. Temperature trend analysis: Automatically measure particle size and Zeta potential according to the set temperature range, and detect the temperature trend of sample particle size or potential.

7. Capillary sample cell: An improved flat bottomed U-shaped capillary sample cell is used to measure Zeta potential. Due to the horizontal bottom of the sample cell, the electric field strength is more uniform than traditional capillary sample cells, reducing measurement errors and improving the measurement accuracy and repeatability of Zeta potential.

8. Enhanced Phase Analysis Light Scattering Technology (PALS): By measuring the phase change of the light beat signal, the Zeta potential of particles is obtained, with a measurement resolution two orders of magnitude higher than electrophoretic light scattering method.

9. Data output: Provides data output function, making it convenient for users to view and compare measurement results in customized graphs and tables

10. Standardized Operation: The software has a Standard Operating Procedure (SOP) function, which enables measurements between different laboratories and experimenters to be conducted according to the same standard, resulting in more comparable measurement results.

11. Intelligent measurement: Automatically adjust scattered light intensity and optimize photon correlation parameters to adapt to different samples, making measurement so easy.

12. Regulatory software: The software complies with the requirements of FDA 21CFR Part 11, can set/modify user group access permissions, has electronic record/electronic signature and audit tracking functions, and meets the regulatory requirements of pharmaceutical companies.

parameter	technical indicators
model	939SZ
function	Particle size, Zeta potential, molecular weight, temperature trend
granularity
measurement method	Dynamic Light Scattering (DLS), Multi Angle Dynamic Light Scattering (MADLS), Back Dynamic Light Scattering (BSDLS)
Analysis pattern	CUMULANT, CONTIN, NNLS automatic selection
Measure angle	11°，90°，175°
Particle size range	0.3nm-15μm*
accuracy	Less than 1% (NIST traceable latex standard)
repetitiveness	Less than 1% (NIST traceable latex standard)
Minimum sample size	3μL*
Minimum sample concentration	0.1mg/mL lysis
Maximum sample concentration	40%w/v*
Zeta potential
measurement method	Phase Analysis Light Scattering (PALS)
Measure angle	11°
Zeta potential range	No practical limitations
Electrophoretic mobility range	>±20μ·cm/V·s
Maximum conductivity	270mS/cm*
Suitable particle size range for measurement	3nm~120μm*
molecular weight
measurement method	SLS and DLS
Molecular weight range	340Da ~ 20MDa
system
laser	532nm solid-state laser, 50mW*
transmittance	0% -100% continuous adjustment
detector	High sensitivity PMT or APD*
correlator	Minimum sampling time 25ns, dynamic range greater than 1011
Temperature control range	-10°~120°C
Temperature control accuracy	±0.1°C
Condensation control	Dry air blowing
working environment	Temperature+10 ° C~+35 ° C, relative humidity 35%~80%, no condensation
computer interface	USB 2.0 or above
power supply	AC100V~240V，50/60Hz， Maximum power 120W
size	580mm×365mm×195mm
weight	18kg
Computer operating system	Windows 10 32/64 bit operating system
Regulatory software	Compliant with the requirements of FDA 21 CFR Part 11, users can flexibly set usage permissions and have electronic signatures Audit tracking function, * compliant with regulatory requirements of pharmaceutical companies

Depends on the sample and selected components

　　Nano particle size and Zeta potential analyzerApplication in the field of nanoparticle particle size measurement:

1. Nanomaterials: Nanomaterials not only have a lower melting point, but also a lower phase transition temperature, allowing solid-state reactions to occur at low temperatures, resulting in composite materials with good sintering performance. They can be used to study the influence of particle size on material properties of nano metal oxides, nano metal powders, and nano ceramic materials.

2. Biopharmaceuticals: can analyze proteins DNA、RNA、 Viruses, down to the granularity of various antigens and antibodies.

3. Fine chemical engineering: can be used to search for optimized particle size distribution of nanocatalysts to reduce chemical reaction temperature and improve reaction rate.

4. Paint and coating: it can be used to measure the particle size of nano particles in paint, coating, silica gel, polymer latex, water/oil lotion, pigment, ink, toner, cosmetics and other samples.

5. Food and drugs: Coating nanoparticles on the surface of drugs can enable efficient sustained release and can be made into targeted drugs, which can be used to control the size of drug particles in order to better exert the therapeutic effect of drugs.

6. Aerospace: Adding nano metal powder to rocket solid propellants can significantly improve the combustion performance of the propellant and can be used to study the optimized particle size distribution of metal powder.

7. National Defense Technology: Nanomaterials increase the efficiency of converting electromagnetic energy into thermal energy, thereby improving the absorption performance of electromagnetic waves, and can be made into electromagnetic wave absorbing materials. Different particle size nanomaterials have different optical properties and can be used to study the performance of absorbing materials.

939SZ

　　Nano particle size and Zeta potential analyzerApplication in Zeta potential measurement field:

1. Surface reforming control of pharmaceuticals and industrial latex

2. Functional analysis and research of surfactants

3. Research on the Performance of Pulp Additives

4. Functional analysis of electrolytic polymers

5. Protein functional analysis and research

6. Dispersion and coagulation control of food, perfume, drugs, cosmetics and other emulsions

7. Research on ribosome dispersion and aggregation control

Attachment

	Disposable U-shaped capillary sample cell (OPZ0090) Used for measuring Zeta potential. The capillary sample cell is U-shaped, and due to the horizontal bottom of the cell, the electric field strength at the measurement point is more uniform than that of traditional semi-circular capillary sample cells, thereby improving the measurement accuracy and repeatability of Zeta potential. This sample cell is a disposable sample cell that can avoid cross contamination of samples during Zeta potential measurement. Although it is a disposable sample cell, as long as the measurement area of the sample cell is kept clean and free of scratches, and the electrode pads are bright and free of oxidation, it can be reused. Suitable for water-based dispersants. Sample volume: 0.7mL-0.9mL, plug the plug tightly, and ensure that the sample is immersed in the electrode pads on both sides.
	Insertion type flat electrode sample cell (DIP0770) Used for measuring Zeta potential. The plug-in flat electrode sample cell should be used in conjunction with a polystyrene sample cell or a glass sample cell. The sample pool is corrosion-resistant, easy to clean, and reusable Can be used to measure the Zeta potential of samples for both aqueous and non-aqueous dispersants. Sample size: 0.7mL-1.0mL.
	Disposable polystyrene sample pool (OPP0100) Used for measuring particle size and molecular weight. Disposable polystyrene sample pool to avoid cross contamination of samples. Can be paired with an inserted flat electrode to measure the Zeta potential of the sample. Suitable for water-based dispersants. Minimum sample size: 0.8mL.
	Reusable Glass Sample Cell (OPG0002) Used for measuring particle size and molecular weight. Can be paired with an inserted flat electrode to measure Zeta potential. The sample pool is corrosion-resistant, easy to clean, and reusable. Compatible with both water-based and non-aqueous dispersants. Minimum sample size: 0.8mL.
	Reusable quartz sample cell (OPQ0002) Used for measuring particle size and molecular weight. Higher light transmittance, better solvent resistance, easy to clean, and reusable. Compatible with both water-based and non-aqueous dispersants. Minimum sample size: 0.8mL.
	Disposable trace sample pool (OPM0010) Used for measuring particle size. Disposable polystyrene micro sample pool to avoid cross contamination. Suitable for water-based dispersants. Only applicable for measuring particle size at a 90 degree angle. Minimum sample size: 50 μ L.
	Disposable capillary micro sample pool (OPM0003) Used for measuring particle size, expandable particle size measurement range, and able to solve the particle size measurement needs of valuable samples with extremely small sample sizes in the biopharmaceutical field. Compatible with both water-based and non-aqueous dispersants. Only applicable for measuring particle size at a 90 degree angle. Minimum sample size: 3 μ L.