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AOPUTE Technology (Shanghai) Co., Ltd

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    Room 602, Building A, Minggu Science and Technology Park, No. 7001 Zhongchun Road, Minhang District, Shanghai

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Nano Particle Analyzer

NegotiableUpdate on 05/07
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Overview

The 9x9 series nanoparticle size and Zeta potential analyzer uses a high-speed digital correlator as its core device, measuring particle size using dynamic light scattering technology, Zeta potential using phase analysis light scattering technology, and molecular weight using static light scattering technology. The measurement results are accurate and reliable, making it a reliable choice for measuring nanoparticle size and Zeta potential.

Product Details

1. All fiber optical path: By using all fiber optical path instead of discrete optical path, the reference light and scattered light signals are no longer affected by dust and stray light interference, significantly improving the signal-to-noise ratio and anti-interference ability.

3. Large dynamic range high-speed digital correlator: Using a photon correlator with high-speed and low-speed channels, it effectively solves the contradiction between hardware resources and channel quantity, and obtains real-time correlation functions with large dynamic range and stable baseline.

4. Data filtering function: Introducing the method of quantile detection for outliers, identifying scattered light data affected by dust interference, and removing outliers to improve the accuracy of granularity measurement results.

5. Temperature trend analysis: Automatically measure particle size and Zeta potential according to the set temperature range, and detect the temperature trend of sample particle size or potential.

8. Data output: Provides data output function, making it convenient for users to view and compare measurement results in customized graphs and tables

9. Standardized Operation: The software has a Standard Operating Procedure (SOP) function, which enables measurements between different laboratories and experimenters to be conducted according to the same standard, resulting in more comparable measurement results.

10. Intelligent measurement: Automatically adjust scattered light intensity and optimize photon correlation parameters to adapt to different samples, making measurement so easy.

11. Regulatory software: The software complies with the requirements of FDA 21CFR Part 11, can set/modify user group access permissions, has electronic record/electronic signature and audit tracking functions, and meets the regulatory requirements of pharmaceutical companies.

parameter

technical indicators

model

919S

function

Particle size, molecular weight, temperature trend

granularity


measurement method

Dynamic Light Scattering (DLS)

Analysis pattern

CUMULANT, CONTIN, NNLSauto-select

Measure angle

90°

Particle size range

0.3nm-15μm*

accuracy

Less than 1% (NIST traceable latex standard)

repetitiveness

Less than 1% (NIST traceable latex standard)

Minimum sample size

3μL*

Minimum sample concentration

0.1mg/mLlysozyme

Maximum sample concentration

40%w/v*

molecular weight


measurement method

SLSAnd DLS

Molecular weight range

340Da ~ 20MDa

system


laser

532nmSolid state laser, 50mW*

transmittance

0%-100%Continuous adjustment

detector

High sensitivity PMT or APD*

correlator

Minimum sampling time 25ns, dynamic range greater than 1011

Temperature control range

-10°*~120°C*

Temperature control accuracy

±0.1°C

Condensation control

Dry air blowing

working environment

Temperature+10 ° C~+35 ° C, relative humidity 35%~80%, no condensation

computer interface

USB2.0or above

power supply

AC100V~240V, 50/60Hz, Maximum power 120W

size

580mm×365mm×195mm

weight

18kg

Computer operating system

Windows 10 32/64bit operating system

Regulatory software

Compliant with the requirements of FDA 21 CFR Part 11, users can flexibly set usage permissions and have electronic signatures

Audit tracking function, * compliant with regulatory requirements of pharmaceutical companies

*Depends on the sample and selected components


Application of nanoparticle size and Zeta potential analyzer in the field of nanoparticle size measurement:

1. Nanomaterials: Nanomaterials not only have a lower melting point, but also a lower phase transition temperature, allowing solid-state reactions to occur at low temperatures, resulting in composite materials with good sintering performance. They can be used to study the influence of particle size on material properties of nano metal oxides, nano metal powders, and nano ceramic materials.

2. Biopharmaceuticals: can analyze proteins DNA、RNA、 Viruses, down to the granularity of various antigens and antibodies.

3. Fine chemical engineering: can be used to search for optimized particle size distribution of nanocatalysts to reduce chemical reaction temperature and improve reaction rate.

4. Paint and coating: it can be used to measure the particle size of nano particles in paint, coating, silica gel, polymer latex, water/oil lotion, pigment, ink, toner, cosmetics and other samples.

5. Food and drugs: Coating nanoparticles on the surface of drugs can enable efficient sustained release and can be made into targeted drugs, which can be used to control the size of drug particles in order to better exert the therapeutic effect of drugs.

6. Aerospace: Adding nano metal powder to rocket solid propellants can significantly improve the combustion performance of the propellant and can be used to study the optimized particle size distribution of metal powder.

7. National Defense Technology: Nanomaterials increase the efficiency of converting electromagnetic energy into thermal energy, thereby improving the absorption performance of electromagnetic waves, and can be made into electromagnetic wave absorbing materials. Different particle size nanomaterials have different optical properties and can be used to study the performance of absorbing materials.



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