Maintenance of intelligent dissolution tester

Chongqing Yixiu Technology Service Co., Ltd. specializes in providingMaintenance of intelligent dissolution testerservice

The intelligent dissolution meter imitates the gastrointestinal tract of humans or animals, simulates the peristalsis of intestinal function, and adds digestive reagents similar to those of humans or animals to study the digestive science of food or drugs using the dissolution meter. Dissolution testers are more commonly used for drug research. The research on drugs has a one-to-one correspondence between the composition of drugs and their therapeutic effects. The study of drug efficacy is a prerequisite. When a certain drug is proven to be effective for a certain disease, it becomes very important to explore the production process of the drug. If a drug with efficacy cannot be absorbed by the human body, or the absorption efficiency is low, or the dissolution rate is too fast (because some drugs require slow onset of efficacy for patients). The dissolution and absorption of drugs determine whether they should be made into granules, capsules, or liquid form. So the study of dissolution rate is an experimental process in pharmaceutical science research, and it is also a necessary monitoring step for drug production quality control.

Traditionally, only poorly soluble drugs were considered to be concerned with solubility, but contemporary medicine has shown that soluble drugs also need to be considered for solubility. The formula and process of the formulation determine the dissolution properties of the drug.Drug bioavailability and efficacyIt is directly related to the drug dissolution rate.

The disintegration time limit test cannot replace the study of drug dissolution. The particle size of the disintegrator sieve is only a parallel constant standard, which can be used to compare the parallelism of different drugs. Disintegration is only the initial stage of drug dissolution, and the subsequent dispersion and dissolution process cannot be controlled by the disintegration time limit test. Moreover, the disintegration of solid preparations is also affected by prescription design, preparation, storage process, and many complex factors in the body. Therefore, the disintegration time limit test cannot objectively reflect the relationship and influence between drugs and excipients, while the dissolution test includes the disintegration and dissolution process. Therefore, studying dissolution has more important significance.

Yi Xiu Technology specializes in providing various brandsMaintenance of intelligent dissolution testerservice Including maintenance services for domestic dissolution testers and imported dissolution testers.