LNP microfluidic control backup device

Microfluidic control equipment is a microfluidic device that can be used for scientific research, early process validation, and technology development. Using an injection pump as the power source, experiments can be conducted with fewer samples.

Microfluidic control backup deviceProduct Introduction: It is a microfluidic device that can be used for scientific research, early process validation, and technology development. Using an injection pump as the power source, experiments can be conducted with fewer samples.

Product Introduction

Microfluidic technology is a technique based on (micro) fluid mechanics theory that enables sample preparation and processing in pipelines. Combining the physical and chemical models of microfluidics with fluid mechanics theory can achieve functions such as mixing, emulsification, separation, and purification of samples.

The microfluidic control preparation system is connected to the microfluidic chip through a preparation pump and a high-pressure delivery pump. Phase A and phase B can be delivered to the chip at a constant speed in a certain proportion for mixing and emulsification. By designing different channel structures and controlling different velocities in microfluidic chips, the sample can achieve turbulent, laminar, or atomized states within the desired range of particle size * up to 100nm and PDI below 0.1. Based on microfluidic technology, the synthesis process can be precisely controlled, and nanocarriers with narrower particle size distribution, higher drug loading capacity, and better stability can be synthesized. Moreover, this technology has a high degree of repeatability. Therefore, microfluidic technology has great potential for application in the production of nanomaterials.

Introduction to Microfluidic Chips:

Microfluidic chip, also known as Lab-on-a-Chip, is a scientific technology mainly characterized by manipulating fluids in micro nano scale space. It has the ability to miniaturize basic functions of biological, chemical and other laboratories such as sample preparation, reaction, separation and detection onto a few square centimeter chip. Its basic feature is the flexible combination and scale integration of multiple unit technologies on a controllable micro platform.

Microfluidic control backup deviceApplication area: 

Liposome preparation

Encapsulation of mRNA lipid nanoparticles (LNP)

Preparation of insoluble drug micelles (nanocrystals, boron drugs, etc.)

Product advantages:

The performance is comparable to imported products, and the price is less than one-fifth of imported products.

The dead volume is small, less than 0.05ml, with no official connection in the middle. The part in contact with the liquid is a disposable syringe and 316L stainless steel chip, which can be steam sterilized.

316L stainless steel chips have no limit on usage times, no consumable costs, and can withstand organic solvents such as chloroform.

The chip interface has a withstand voltage of 0.7Mpa, ensuring no material leakage during use.

It has a heating function, which can be used for mRNA LNP encapsulation or liposome encapsulation, and can be heated above the phospholipid phase transition temperature.

The device has a small size and can be operated in a biosafety cabinet to avoid contamination.

Product Parameters: