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Shanghai Qiansi Biotechnology Co., Ltd
Human Cartilage Glycoprotein 39 Kit
NegotiableUpdate on 05/06
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Overview
The human cartilage glycoprotein 39 kit often uses ELISA technology. High sensitivity, strong specificity, good stability, and easy operation. Used for scientific research and clinical practice, it can detect YKL-40 content in various samples.
Product Details
Human Cartilage Glycoprotein 39 Kit
Human Cartilage Glycoprotein 39 KitIt occupies a key position in the field of medical testing and is a powerful tool for researchers and clinical physicians to explore disease mechanisms and diagnose diseases.
From the perspective of detection principles, most of them rely on enzyme-linked immunosorbent assay (ELISA) technology. Inside the reagent kit, the microplate serves as a solid carrier and has been carefully coated with specific antibodies against human cartilage glycoprotein 39 (YKL-40). When adding the sample to be tested, YKL-40 in the sample is like finding a "compatible partner" and quickly binds specifically to the solid-phase antibody. Subsequently, the enzyme labeled second antibody is added, which can accurately connect with the solid-phase antibody bound to YKL-40, forming a stable "solid-phase antibody YKL-40 enzyme labeled secondary antibody" complex structure. After adding the substrate, the enzyme plays a catalytic role and the substrate begins to undergo color reaction. The degree of color reaction is closely related to the content of YKL-40 in the sample, showing a positive correlation. Researchers or medical staff can use an enzyme-linked immunosorbent assay (ELISA) reader to measure the absorbance after the reaction, and then compare it with the standard curve provided by the reagent kit to accurately calculate the concentration value of YKL-40 in the sample.
The characteristics of this reagent kit are extremely outstanding. It has high sensitivity, even if the disease is still in its early stages and there are only very small changes in YKL-40 levels in the body, it can be accurately detected. In terms of specificity, the antibodies have undergone layers of screening and optimization, and only produce specific reactions to YKL-40, which can avoid cross reactivity with other similar proteins to the greatest extent possible, ensuring the accuracy of the detection results. At the same time, it also exhibits excellent stability, thanks to strict production processes and quality control systems. Under the specified storage conditions of 2-8 ℃, the performance of the reagent kit remains stable throughout its validity period, and the test results between different batches have good consistency. On the operational level, it is also relatively simple. The reagent kit comes with detailed instructions, and the reagent components should be complete. After simple training, operators can carry out testing work according to standardized procedures.
In terms of applicability, in the field of scientific research, it helps researchers to deeply analyze the expression changes of YKL-40 in normal physiological processes and various pathological states, providing key clues for revealing the pathogenesis of diseases. In clinical diagnosis, the same effect is significant. For example, in patients with arthritis, the level of YKL-40 in their serum or joint fluid often increases. Testing this indicator helps doctors evaluate the progression and treatment effectiveness of arthritis. In tumor research, some tumor cells overexpress YKL-40, and detecting it can assist in tumor diagnosis, prognosis evaluation, and efficacy monitoring. In summary, the human cartilage glycoprotein 39 kit continues to play an important role in medical research and clinical practice due to its unique advantages.
