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Shanghai Haoyun Instrument Equipment Co., Ltd

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High speed countercurrent chromatograph

NegotiableUpdate on 05/24
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Overview

High speed counter current chromatography (HSCCC) is suitable for separating small and medium-sized substances such as Chinese herbal medicine, synthetic chemicals, antibiotics, etc., and accumulating small amounts of active ingredient monomers for subsequent scientific research; Especially suitable for the separation of active ingredients with strict requirements for environmental temperature. As an industry leader in the field of high-speed countercurrent chromatography with multiple separation columns, the company has developed and mass-produced the TBE series of new multi separation columns with independent intellectual property rights, accounting for 85% of China's countercurrent chromatography. Main features: high separation flow rate, high injection volume, and high separation efficiency.

Product Details

High speed countercurrent chromatographTechnical Specifications:

Separation column: Three separation columns
Switching valve: four-way switching, dual six way valve
Host capacity: 300ml
Injection ring: 20ml
Separation amount: on the order of mg-10g
Speed range: 0-1000rpm stepless variable frequency speed regulation
Separation speed: 700-900rpm
Flow rate range: 0.1-50.0ml/min
Separation flow rate: 5.0-30 ml/min
Maximum pressure: 2MPa
Temperature control: 5-40 ℃
Host size: 500 × 760 × 830
Host power: 500W
Net weight: 180 kilograms

High speed countercurrent chromatographKey Features:
High separation flow rate, high injection volume, high separation efficiency, dual pump balance function.

asMulti separation columnAs the new owner of the country and the industry leader in high-speed countercurrent chromatography, the company has developed and mass-produced the TBE series of new multi separation columns with independent intellectual property rightsOccupying 85% of China's counter current chromatography.

The company has currently developed 9 models in three major series: analytical, semi prepared, and preparedIt integrates extraction, separation, purification, and preparation, and can provide advanced separation and purification facilities for various universities, research institutes, and pharmaceutical enterprises.

Dual pump balancing function:
The system is equipped with two plunger pumps, which can simultaneously pump the upper and lower phases, shorten the system balance time, and improve work efficiency; Within the range of maximum natural equilibrium retention rate, experiments can be conducted by simultaneously pumping the upper and lower phases according to different retention rates.

Infusion system: high precision, low pulse, precise flow rate
The plunger pump is a key technology that ensures precise delivery of flow rate, accurate to 0.01 milliliters per minute. It adopts a dual plunger series mode and a floating plunger design.
The microprocessor controlled, high-speed dual drive, and parallel pump heads have high-speed chamber pressure feedback, compensating for refilling and solvent compression effects, achieving precise and highly reproducible flow rates over a wide dynamic range. The wheel curve compensation technology is used to effectively control flow pulsation.

Temperature control function of constant temperature water bath:
Water bath temperature control has better cooling effect than any other in the industry. Because the heat transfer coefficient of water is more conducive to heat transfer, the same goes for increasing temperature; The temperature control function is not only for cooling, but also for increasing the temperature.

Configuration sheet:
One host, two plunger pumps, one full wavelength detector, one circulating water bath, one air compressor, one built-in chromatography workstation, and one HSCCC solvent selection software.

Partial transaction customers:
Institute of Process Engineering, Chinese Academy of Sciences (Beijing)
Institute of Botany, Chinese Academy of Sciences (Beijing) Institute of Medicinal Plants, Chinese Academy of Medical Sciences (Beijing)
Beijing Baotai Ningtang Biotechnology Co., Ltd. Tianjin Tasly Pharmaceutical Co., Ltd. Jilin Institute of Traditional Chinese Medicine
Changchun University of Traditional Chinese Medicine Second Military Medical University School of Pharmacy (Shanghai) National Engineering Technology Research Center for Traditional Chinese Medicine Pharmaceutical (Shanghai)
Shanghai University of Traditional Chinese Medicine, Shanghai Pharmaceutical Industry Research Institute, School of Pharmacy, China Pharmaceutical University
School of Tea, Zhejiang University, School of Chemical Engineering, Zhejiang University of Technology, School of Pharmacy, Zhejiang University of Technology
New Materials Laboratory, Tsinghua University Research Institute, Shenzhen, School of Pharmacy, Sun Yat sen University, School of Chemistry and Chemical Engineering, South China University of Technology
Shandong Green Leaf Natural Medicine Research and Development Co., Ltd., Department of Chemistry, Xiamen University, Fujian Institute of Microbiology, National Medical Administration
School of Chemical Engineering, Liaocheng University, Shandong Province, School of Life Sciences, Southwest Normal University (Chongqing), West China Hospital, Sichuan University
Northwest University School of Life Sciences

Main advantages:
No sample loss - because both phases (mobile phase and stationary phase) are liquids, the sample can be fully recovered
High throughput technology - liquid/liquid distribution system not only helps to increase the solubility of the sample, but also increases the sample loading capacity, achieving high-throughput effects
Low solvent consumption - this technology only uses a solvent amount equivalent to 10% of the unprocessed sample mass
Process amplification is very easy - due to the easy regeneration of column fillers, separation conditions are very easy to replicate under any conditions and at all levels of equipment operation.

Keywords: High efficiency countercurrent chromatography, centrifugal distribution chromatography, HSCCC,HPCCC,CPC