Habaroside extracted from black ginseng or African devil's claw

NegotiableUpdate on 12/24

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Overview

Habaroside extracted from Scrophularia or African devil's claw $r $nCAS: 19210-12-9 $r $nPurity (HPLC): ≥ 98% $r $nC24H30O11494.4884 $r $n Experimental uses: Cell experiments, animal experiments

Product Details

Product Name:Habaroside extracted from black ginseng or African devil's claw

Product ID: E-0052

CAS ：19210-12-9

English name: Harpagoside

Content (HPLC)>98%

Molecular formula: C24H30O11

Molecular weight (g/mol) 494.4884

Product Appearance: White Powder

Relatively stable in nature

Habaroside extracted from black ginseng or African devil's clawSource of extraction: Harpagophytum procumbens, D.C

Under the content determination item of Xuanshen in the 2005 edition of the Chinese Pharmacopoeia:

Chromatographic conditions and system suitability test: using octadecylsilane bonded silica gel as filler; Using acetonitrile as mobile phase A and 1% acetic acid solution as mobile phase B, perform gradient elution as specified in the table below; The detection wavelength is 278nm. The theoretical number of plates should not be less than 5000 based on the peak of harpagoside.

0-20 minutes, mobile phase A (%): 20 → 50, mobile phase B (%): 80 → 50

Preparation of test solution: Take about 0.5g of powder from this product, weigh it accurately, place it in a conical flask with a stopper, add 50ml of 30% methanol accurately, seal it tightly, weigh it, soak for 1 hour, sonicate (power 500W, frequency 40KHz) for 30 minutes, cool it down, weigh it again, make up for the lost weight with 30% methanol, shake well, filter, and take the continuous filtrate.

Habaroside can promote spleen function in mice with yin deficiencylymphocyteProliferation can induce splenic lymphocytes to produce IL-2, reduce the content of cAMP in the plasma of Yin deficiency mice, and adjust the cAMP/cGMP ratio to the level of the normal control group, thus restoring the suppressed immune function.