HEK-293T/ACE2 human renal epithelial cell line

HEK-293T/ACE2 human renal epithelial cell line

Specification: 1 * 105-1 * 106 or T25 culture bottle cycle; 2-week validity period: 1 year storage: -20 degrees Celsius cultivation conditions: DMEM+10% FBS

HEK-293T/ACE2 is a stable engineering cell line constructed based on HEK-293T cells. The human angiotensin-converting enzyme 2 (ACE2) gene is integrated into the cell genome through gene editing, achieving stable expression of ACE2 protein on the cell membrane surface. It is a mechanism for coronavirus invasion and disease resistancePoisonous medicineThe core tool for screening substances and evaluating vaccine efficacy, Cell

1. Study on the Mechanism of Coronavirus: Analyzing the Molecular Mechanism of S Protein-ACE2 Binding and the Host Cell Signaling Pathway Response after Virus Invasion

2. Disease resistancePoisonous medicineScreening of substances: Screening for small molecule inhibitors that block S-ACE2 binding, neutralizing antibodies, or drugs that inhibit virus replication

3. Vaccine efficacy evaluation: Through pseudo virus neutralization experiments, the neutralizing activity of vaccine immune serum is detected to evaluate the protective efficacy of the vaccine

4. Research on receptor function: Exploring the role of ACE2 protein in physiological processes such as cell signaling and apoptosis

HEK-293T/ACE2 human renal epithelial cell line

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Used in the analysis of biological samples, such as conducting experiments using mass spectrometry methods
Supplier: Beijing Keyuan Xinsheng Biotechnology Co., Ltd. Main business: Human derived cells: adherent human liver cells, suspended human liver cells. SLC transporter ABC vesicle
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