Grinding machine

Shanghai Lichen is deeply involved in the field of sample pretreatment equipment. With mature research and development technology and precise market insights, it has launched a variety of grinding products that are suitable for different experimental scenarios and meet diverse grinding needs. Among them, the PTG series portable grinder, FG series frozen grinder, and ETG series efficient tissue cell grinder are the three core series, which are tailored to the specific needs of portable grinding, low-temperature high-throughput grinding, and efficient tissue cell fragmentation. They have their own focuses on technical design, performance parameters, and application scenarios, and also have the advantages of high cost-effectiveness and strong adaptability of domestic instruments. They are widely used in various fields such as medical and health, environmental protection, food/agricultural products, agriculture, forestry, animal husbandry, fishery, chemical industry, biotechnology, pharmaceuticals, etc., becoming the core equipment for laboratory sample grinding and processing.

　　Introduction to Lichen Technology Grinding Machine Series Products

Shanghai Lichen is deeply involved in the field of sample pretreatment equipment. With mature research and development technology and precise market insights, it has launched a variety of grinding products that are suitable for different experimental scenarios and meet diverse grinding needs. Among them, the PTG series portable grinder, FG series frozen grinder, and ETG series efficient tissue cell grinder are the three core series, which are tailored to the specific needs of portable grinding, low-temperature high-throughput grinding, and efficient tissue cell fragmentation. They have their own focuses on technical design, performance parameters, and application scenarios, and also have the advantages of high cost-effectiveness and strong adaptability of domestic instruments. They are widely used in various fields such as medical and health, environmental protection, food/agricultural products, agriculture, forestry, animal husbandry, fishery, chemical industry, biotechnology, pharmaceuticals, etc., becoming the core equipment for laboratory sample grinding and processing.

　　1、 PTG series portable grinder - a compact, portable, efficient and versatile choice for basic grinding

The PTG series from Lichen Technology is a lightweight grinding equipment designed specifically for rapid on-site grinding and routine grinding in small laboratories. With its core features of small size, portability, easy operation, and high grinding efficiency, it is suitable for the rapid crushing and grinding needs of hard samples and performs excellently in outdoor testing, on-site sampling, and daily experiments in small laboratories,The reference price is ¥ 5100-5500 per unitIt is a cost-effective basic instrument.

　　（1） Core working principle

The working principle of horizontal three-dimensional vibration is adopted, which is different from traditional unidirectional vibration grinding equipment. The instrument is driven by a motor to achieve composite three-dimensional motion of X and Y axes, which drives the grinding balls/beads in the grinding tank to generate inertial force, repeatedly impacting the sample material located on the curved inner surface with high energy. The sample is crushed and ground through the synergistic effect of impact force and shear force. At the same time, the movement of the instrument adapter can overlap with the movement of the internal grinding ball, allowing the sample to fully contact and mix with the grinding ball. If multiple small diameter grinding balls are used, the mixing and grinding effect can be further improved, ensuring that the sample is ground evenly and without residue. The instrument operates in a circular '8' shape, allowing the movement trajectory of the grinding beads to cover the entire grinding tank, fundamentally avoiding the problem of uneven sample grinding in traditional instruments.

　　（2） Core features of the product

1. Visual operation, convenient parameter setting:Equipped with an LCD display screen, the display content is clear and visible, and parameters such as grinding time and operating status are intuitively presented; Equipped with timing function, the running time can be freely set to meet the grinding time requirements of different samples, and the operation is simple and easy to use.

　　2. Parameter memory makes repeated experiments more efficient:The set grinding parameters have a self memory function, and there is no need to reset the parameters when the instrument is turned off and restarted, greatly improving the efficiency of repeated experiments and reducing manual operation errors.

　　3. Portable and adaptable to multiple scenarios:The instrument has a compact and lightweight appearance, with a net weight of only 2.2Kg and a product size of 220150170mm. It can be easily placed in the corner of the experimental table and is also easy to carry to non laboratory environments such as outdoor sites and sampling points for grinding operations, breaking space limitations.

　　4. Multi sample synchronous grinding to avoid cross contamination:Support simultaneous grinding of multiple specifications of sample tubes, with different models capable of achieving grinding fluxes of 2ml4, 2ml6, and 5ml2 respectively, capable of processing multiple samples simultaneously and improving grinding efficiency; Single tube independent grinding design effectively avoids cross contamination between samples and ensures the accuracy of experimental results.

　　5. Intelligent heat dissipation to extend device lifespan:The internal built-in cooling fan can dissipate the heat generated by the operation of the motor and instrument in a timely manner, avoiding performance degradation caused by long-term high temperature operation of the equipment, effectively extending the service life of the motor and the whole machine, and ensuring stable operation of the equipment.

　　6. Low noise operation and adequate safety protection:The working noise is less than 54dB, far lower than conventional laboratory grinding equipment, creating a quiet experimental environment; Equipped with a work safety lock, if there is an abnormal opening during operation, the instrument will automatically stop running, and it also has an automatic alarm reminder function to ensure the safety of experimental operations.

　　7. Easy maintenance and stable grinding effect:The overall structure design of the instrument is simple, with no complex and vulnerable parts, and simple daily cleaning and maintenance operations; The three-dimensional vibration grinding mode ensures uniform grinding, and the discharge particle size can be stably controlled within 0.01-0.5mm, meeting the grinding particle size requirements of conventional hard samples.

　　（3） Detailed technical parameters

At present, there are three models launched: LC-PTG-4, LC-PTG-6, and LC-PTG-2. The core performance of the three models is the same, with only differences in grinding flux. The specific technical parameters are shown in the table below:

parameter item	parameter value
Product Model	LC-PTG-4（2ml4）、LC-PTG-6（2ml6)、LC-PTG-2（5ml*2)
power supply voltage	DC24V 4A
power	0.6KW
display mode	LCD display screen
Grinding flux	2ml4/2ml6/5ml * 2 (corresponding to different models)
Timing	1-9999s
grinding speed	4000RPM
safety protection	Work safety lock
operating noise	＜54dB
working principle	3D motion mode grinding
discharge particle size	0.01-0.5mm
Sample applicable	Hard sample
Net weight	2.2Kg
Product size (L × W × H)	220150170mm

　　（4） Application Fields

As a domestically produced basic grinding equipment, it has strong adaptability and is mainly used in four major fields: medical and health, environmental protection, food/agricultural products, agriculture, forestry, animal husbandry, and fishery. It can quickly grind various hard samples, such as grain and nut hard samples in food testing, soil and ore samples in environmental testing, crop seeds and hard plant tissues in agriculture, forestry, animal husbandry, and fishery fields, and hard medicinal materials and experimental consumables in medical and health fields. It is suitable for routine laboratory experiments and can also meet the sample pretreatment needs for rapid on-site testing.

　　2、 FG series cryogenic grinder - a professional grinding equipment with low temperature and high flux, suitable for thermosensitive samples

Lichen Technology FG series is a professional grade grinding equipment designed for high-throughput grinding of thermosensitive samples and various types of samples. It integrates low-temperature refrigeration technology and high-throughput grinding design, and can achieve integrated processing of dry grinding, wet grinding, low-temperature grinding, and homogenization. It is particularly suitable for grinding thermosensitive samples in the biological field, effectively avoiding component degradation caused by heat generation due to grinding friction,The reference price is between ¥ 50900 and ¥ 61900 per unitIt is the grinding choice for fields such as biopharmaceuticals, molecular biology, and food testing.

　　（1） Core working principle

The composite working principle adopts the vertical vibration mode of grinding beads combined with the low-temperature refrigeration technology of imported compressors. On the one hand, high-frequency vertical vibration of grinding beads is achieved through motor drive. During the vibration process, the grinding beads generate strong impact force, shear force, and grinding force, which quickly crushes the sample. The vertical vibration mode makes the contact between the grinding beads and the sample more complete and the grinding effect more uniform; On the other hand, the instrument is equipped with an imported high-efficiency energy-saving compressor, which can achieve wide range temperature control of -50~37 ℃, with a temperature control accuracy of 0.5 ℃. During the grinding process, the sample is always in a fully enclosed low-temperature environment. By low-temperature embrittlement of the sample, it not only reduces grinding resistance but also effectively inhibits the thermal degradation of thermosensitive samples (such as RNA, enzymes, proteins, etc.), ensuring the biological activity of the sample. The instrument is designed using international DIN methods and has stable overall performance. It can quickly and effectively grind 96 samples simultaneously within 3 minutes, greatly improving the efficiency of sample pretreatment.

　　（2） Core features of the product

　　1. Touch operation, user-friendly human-computer interaction:Equipped with a LCD touch screen, the display is intuitive and clear, with sensitive and rapid response. Parameters such as grinding time, temperature, and homogenization speed can be directly set on the screen, making operation convenient and parameter adjustment precise.

　　2. Ultra high throughput, significant grinding efficiency:We have launched two models, LC-FG-48 and LC-FG-96, which support synchronous grinding of 48 and 96 sets of samples respectively. They are compatible with various specifications of sample tubes such as 0.2-0.5ml, 2ml, 5-15ml, 25ml, and 50ml, and can handle grinding needs for multiple volumes and types of samples in a single batch, meeting the sample pretreatment requirements for high-throughput experiments.

　　3. Multi mode grinding with strong adaptability:Supporting four modes of dry grinding, wet grinding, low-temperature grinding, and homogenization treatment, this equipment can routinely crush biological samples such as plants, animals, bacteria, yeast, as well as soft and medium hard samples such as textiles, PCB boards, paper, and soil. It can also perform low-temperature protective grinding on thermosensitive biological materials, meeting various experimental needs.

　　4. Fully enclosed grinding to prevent cross contamination:During the grinding process, the sample is in a fully enclosed state, and the sample tube is isolated from the grinding chamber, which not only avoids contact contamination between the sample and the external environment, but also prevents cross contamination between different samples, ensuring the reliability of the experimental results.

　　5. Brushless variable frequency motor, low noise and energy-saving:Equipped with a brushless variable frequency motor, it has low noise and low energy consumption during operation, stable motor performance, no carbon brush wear issues, long service life, and reduces equipment maintenance costs in the later stage.

　　6. Stainless steel inner cavity, easy to clean and disinfect:Adopting a design without vulnerable parts, the grinding chamber is made of stainless steel material, which is corrosion-resistant and easy to clean. It can be disinfected in various ways such as high temperature and alcohol, meeting the sterile operation requirements in the fields of biological experiments and pharmaceuticals.

　　7. Complete accessories to meet diverse needs:Standard adapter and various specifications of grinding beads ranging from 0.1 to 30mm can be flexibly selected according to sample hardness and particle size requirements, without the need for additional consumables, to meet the grinding needs of different types of samples.

　　8. Intelligent security protection, more reassuring operation:Equipped with a switch sensor, the instrument will automatically stop grinding when the lid is not closed, avoiding equipment damage or experimental accidents caused by misoperation; Imported compressors come with overheat and overpressure protection to ensure stable operation of the refrigeration system.

　　9. Free of liquid nitrogen operation, more convenient to use:Adopting an integrated refrigeration design, there is no need to equip an additional liquid nitrogen tank for low-temperature treatment. Precise temperature control can be achieved through the instrument's own compressor, simplifying the experimental operation process and reducing experimental costs and safety risks.

　　3） Detailed technical parameters

The FG series cryogenic grinder includes two models, LC-FG-48 and LC-FG-96, with the same core refrigeration and grinding performance, except for differences in sample processing flux. The specific technical parameters are shown in the table below:

parameter item	parameter value
Product Model	LC-FG-48、LC-FG-96
input power	AC220V/50Hz
power	375W
display mode	LCD touch screen
working hours	0s~9999s
Homogenization speed	0~70Hz/s
Compatible sample size	LC-FG-48：48*（0.2~0.5ml）/482ml/12（5~15ml）/425ml/250ml； LC-FG-96：96*（0.2~0.5ml）/962ml/12（5~15ml）/425ml/250ml
discharge particle size	About 5 μ m (below 0.01mm)
Cooling function	have
temperature range	-50~37℃
temperature control accuracy	0.5℃
Grinding ball diameter	0.1~30mm
Grinding method	Wet grinding, dry grinding, low-temperature grinding
safety protection	Switch sensor, automatic shutdown when the lid is not closed

　　（4） Application Fields

With the core advantages of low-temperature refrigeration, high-throughput, and multi-mode grinding, it is widely used in fields such as healthcare, food/agricultural products, chemical industry, biotechnology, and pharmaceuticals/biopharmaceuticals. It is particularly suitable for experimental scenarios that require high sample activity, such as molecular biology, gene testing, proteomics, etc. It can process biological samples such as plant tissues (rice, corn, wheat, etc.), animal tissues (muscle, bone, fur, etc.), bacteria, yeast, viruses, etc. It can also be used for grinding and homogenization of samples such as thermosensitive food ingredients in food testing, polymer materials in the chemical industry, and medicinal raw materials in the pharmaceutical industry. It is the core equipment for laboratory sample pretreatment.

　　3、 ETG series efficient tissue cell grinder - a professional wall breaking equipment for rapid fragmentation and adaptation to tissue cells

The Lichen Technology ETG series is a professional equipment designed for rapid fragmentation and lysis of biological tissues and cell samples. Based on the core principle of bead grinding and combined with motion mode, it can achieve tissue and cell fragmentation in a short period of time, avoiding nucleic acid degradation and protein dissociation, and greatly improving sample yield,The deposit is ¥ 63200 (order quantity ≥ 1 piece)It is a key equipment for organizational cell research in fields such as biological experiments, medical and health care, agriculture, forestry, animal husbandry, and fishery.

　　（1） Core working principle

Based on the principle of bead grinding, a three-dimensional motion mode is adopted to achieve high-frequency multidimensional vibration of the grinding tank through motor drive, which drives the grinding beads and tissue cell samples to undergo intense relative motion. The impact force and shear force of the grinding beads are used to quickly break the physical structure of the cell wall, cell membrane, and tissue fibers, achieving sample fragmentation and lysis. The speed range of the instrument can reach 2000-6000rpm, with a vibration speed of 1.0-12.0m/s. The high-energy motion mode allows 95% of the samples (including plant and animal tissues/organs, microorganisms, spores, hair, etc.) to be broken within 20 seconds. At the same time, the instrument optimizes heat dissipation and motion design, with minimal heating during sample grinding, effectively reducing sample degradation and ensuring the specific activity of extracted proteins and the integrity of nucleic acids.

　　（2） Core features of the product

1. Touch display, precise operation:Equipped with dual display of LCD touch screen and LCD display screen, the operation interface is intuitive and clear, with sensitive and rapid response. It can accurately set parameters such as grinding speed, running time, interval time, etc., to meet the crushing needs of different tissue cell samples.

　　2. Fast and high-throughput, significantly improving experimental efficiency:A single device can simultaneously process 20 × 2ml+4 × 5ml samples, completing the crushing and cracking of 24 samples within 20 seconds. Compared to traditional manual or low-speed grinding equipment, the efficiency is improved by tens of times, effectively shortening the sample pretreatment process.

　　3. Multi type sample adaptation, with a wide range of experimental scenarios:Supporting the processing of various tissue types and cell samples such as plant tissue, animal tissue, microorganisms, spores, hair, cells, etc., it can meet the sample crushing needs of different experiments in molecular biology, cell biology, pathology, etc., with strong adaptability.

　　4. Multi mode grinding, fully functional:Supports four modes of grinding: dry grinding, wet grinding, low-temperature grinding, and homogenization treatment. The grinding method can be flexibly selected according to the characteristics of the sample, such as low-temperature grinding for thermosensitive cell samples and dry grinding for hard plant tissues. One device meets various experimental needs.

　　5. Single sample and single tube to avoid cross contamination:Adopting a single sample and single tube independent operation design, each sample is ground in a dedicated sample tube without contact between samples, eliminating cross contamination and ensuring the accuracy and reliability of experimental results.

　　6. Grind evenly and thoroughly:Adopting a three-dimensional motion mode, the motion trajectory of the grinding beads covers the entire sample tube, with no grinding dead corners, allowing the sample to fully contact the grinding beads, ensuring that tissue cells are crushed, the grinding effect is uniform and sufficient, and the sample yield is greatly improved.

　　7. Low temperature rise of the sample, retaining biological activity:The instrument has optimized the motion structure and heat dissipation design. During the grinding process, the sample temperature is low, which can avoid the degradation of nucleic acids and the dissociation of proteins, ensuring the biological activity of the sample. The extracted protein has high specific activity and good nucleic acid integrity.

　　8. Flexible accessories, customizable and adaptable:The instrument can be equipped with various pre installed extraction tubes, and the sample tube specifications and types can be flexibly selected according to experimental needs without additional processing. It can adapt to different experimental equipment and detection methods, improving the versatility of the equipment.

　　9. Adjustable parameters, suitable for different samples:The speed range is 2000-6000rpm, which can be freely adjusted. The running time is 0-180s and the interval time is 0-999s, which can be accurately set. The grinding parameters can be flexibly adjusted according to the hardness and toughness of the sample, achieving personalized grinding.

　　（3） Detailed technical parameters

The ETG series efficient tissue cell grinder currently mainly promotes the LC-ETG-24 model, with specific technical parameters shown in the table below:

parameter item	parameter value
Product Model	LC-ETG-24
power supply voltage	220V/50Hz
power	500W
Quantity of processed samples	20 × 2ml+4 × 5ml (4500 rpm)
speed range	2000-6000rpm
Oscillation speed	1.0-12.0m/s
Grinding method	Wet grinding, dry grinding, low-temperature grinding
runtime	0-180s
Interval time range	0-999s
screen display	LCD display screen+LCD touch screen
operating noise	70dB
discharge particle size	0.01-0.5mm
Sample applicable	Hard samples, tissue cell samples
Instrument type	Grinding jar
Net weight	20Kg
Product size (L × W × H)	425×320×305mm

　　（4） Application Fields

With the core advantages of rapid crushing, sample activity retention, and no cross contamination, it is mainly used in fields such as medical and health, environmental protection, food/agricultural products, agriculture, forestry, animal husbandry, and fishery. It is particularly suitable for molecular biology experiments, gene testing, vaccine development, agricultural product testing, and other scenarios. It can process plant roots, stems, leaves, seeds and other tissues, animal muscles, organs, hair and other tissues, as well as microbial samples such as bacteria, fungi, spores, and cultured cells. It provides high-quality samples for subsequent experiments such as nucleic acid extraction, protein extraction, and gene amplification, and is a key equipment for sample pretreatment in biological experiments.

　　4、 Comparison and selection suggestions of three major series of grinders

Lichen Technology's PTG, FG, and ETG series grinders are designed with differentiation for different experimental needs, sample types, and usage scenarios. They each have advantages in grinding flux, temperature control, sample adaptation, portability, and other aspects. The following table compares the core characteristics of the three series grinders, which can provide clear reference for experimental selection:

Comparison item	PTG series portable grinder	FG series freeze grinder	ETG series efficient tissue cell grinder
core positioning	Basic portability, regular hard sample grinding	Low temperature high-throughput, thermosensitive multi type sample grinding	Quickly breaking through walls, professionally breaking down tissue cells
reference price	￥ 5100-5500 per unit	￥ 50900-61900/set	Deposit of ¥ 63200 (≥ 1 item)
Grinding flux	2-6 samples (2/5ml)	48/96 samples (0.2-50ml)	24 samples (2/5ml)
temperature control	nothing	Yes (-50~37 ℃, accuracy of 0.5 ℃)	Optional low-temperature grinding
discharge particle size	0.01-0.5mm	About 5 μ m (below 0.01mm)	0.01-0.5mm
grinding speed	Fixed 4000RPM	0~70Hz/s	Adjustable 2000-6000rpm
Net weight	2.2Kg (portable)	73Kg (desktop)	20Kg (desktop)
Sample adaptation	Hard sample	Thermally sensitive samples, soft/medium hard samples, biological samples	Tissue cell samples, hard samples
core advantage	Compact and portable, low noise, high cost-effectiveness	Low temperature refrigeration, high flux, multi-mode grinding	Fast crushing, sample activity retention, no cross contamination

　　Selection Recommendation

1. On site grinding and routine experiments in small laboratories: PTG series portable grinders are preferred. Their compact and portable characteristics can break space limitations, low price, and easy operation advantages are suitable for basic grinding needs, and are suitable for food on-site testing, outdoor environmental sampling, and daily hard sample grinding in small laboratories.

2. High throughput experiments and thermosensitive biological sample grinding: FG series cryogenic grinders are preferred, as their low-temperature refrigeration technology can effectively preserve sample activity. The ultra-high throughput design meets the needs of batch sample processing and is suitable for experimental scenarios such as biopharmaceuticals, molecular biology, and genetic testing.

3. Cell lysis and nucleic acid/protein extraction experiments: The ETG series high-efficiency tissue cell grinder is preferred. Its motion mode can achieve rapid sample fragmentation, and the low temperature design of the sample ensures biological activity, making it suitable for experimental scenarios such as cell biology, pathology, and vaccine development that require high efficiency and activity in sample lysis.