German PreSens oxygen sensor

PreSens optical sensors and measurement systems from GermanyGerman PreSens oxygen sensor/Summary of pH Sensor/CO2 Sensor Brands

Product Introduction

PreSens is an important brand in the field of optical sensing technology in Germany. Its products are mainly aimed at online monitoring and analysis of key parameters such as oxygen, pH, CO2, and are widely used in biotechnology, pharmaceuticals, environmental research, food and beverage, medical life sciences, and industrial technology. Its product system is not a single instrument, but consists of sensors, readout devices, imaging systems, multi parameter monitoring systems, supporting software and accessories, which can be combined according to different experimental systems and application scenarios. PreSens offers a variety of optical measurement products and has over 1000 in stock products, while supporting OEM and customized development.

The core feature of PreSens is the use of optical sensing principles, which can achieve non-destructive, low maintenance, and suitable measurement for online and small volume systems. For users who need to perform testing inside cultivation systems, closed containers, disposable reactors, microfluidic chips, shake flasks, porous plates, pipelines, or packaging, these products have strong application advantages.

Overview of Brand Product System

1、 Optical oxygen analyzer and oxygen sensor

PreSens has the most complete and representative oxygen measurement product line. It has compact single channel equipment suitable for routine laboratory applications, as well as solutions suitable for multi-channel parallel monitoring, on-site portable detection, trace oxygen analysis, and packaging testing. Common representative devices include OXY-1 ST, OXY-1 SMA, OXY-4 series, Microx 4, Microx 4 trace, Fibox 4 trace, etc. Different devices can be paired with miniature sensors, non-invasive sensing patches, immersion probes, and flow cells according to application scenarios, making them suitable for both conventional liquid or gas oxygen analysis and micro environment oxygen gradient measurement, packaging top air analysis, online oxygen monitoring of pipelines, and trace oxygen detection. The oxygen measurement range covers the application range from ppb level trace oxygen to 100% O2.

Taking the OXY-1 series, which is most commonly encountered by laboratory users, as an example, the OXY-1 ST is a very compact USB powered device suitable for various interface solutions such as microsensors, immersion probes, sensing patches, and flow cells; OXY-1 SMA is more suitable for conventional oxygen measurement when paired with PSt3 type sensors. For users who require handheld or on-site work, standalone devices such as Microx 4 and Fibox 4 trace are more suitable for mobile applications; For users who are concerned about packaging, material barrier properties, trace oxygen residue, and sealing evaluation, the adaptability of Fibox 4 trace will be higher.

2、 Optical pH Sensor and pH Measurement System

PreSens's pH product line also uses optical detection methods, with a focus on online pH monitoring in cell culture, microbial culture, disposable reactors, culture bags, shake flasks, porous plates, and circulation systems. Its equipment includes both compact single channel pH meters and online systems suitable for installation in oscillating incubators, as well as a two-dimensional readout unit for imaging applications. Common representative devices include pH-1 SMA LG1, pH-4 mini, and pH readout modules that are compatible with multi parameter systems. PH-1 SMA LG1 can be used in conjunction with non-invasive sensors, immersion probes, and flow cells, and supports temperature compensation, making it suitable for continuous monitoring under temperature changing conditions.

This type of product is more suitable for users who do not want to frequently open the lid for sampling, but also want to continuously obtain information on pH changes during the cultivation process. Especially in cell culture, biotechnology development, and microsystem research, the optical pH scheme is more conducive to establishing continuous data curves compared to traditional offline detection methods, and is also easier to form linkage analysis with parameters such as oxygen and CO2.

3、 Optical CO2 Sensor and CO2 Measurement System

In terms of CO2 monitoring, PreSens provides equipment and sensor combinations for measuring dissolved CO2 in liquid phase, with representative models including CO2-1 ST and matching CO2 immersion probes, sensing patches, and related accessories. CO2-1 ST is suitable for minimally invasive and small volume system measurements, and can be used in environmental research, plant and animal physiology research, and liquid analysis scenarios; For low concentration CO2 monitoring close to environmental levels, low range CO2 probes can also be used to cover applications with approximately 0.02% -5% CO2.

For users who are concerned about cell metabolism, respiration, changes in culture status, and carbonate balance in liquid systems, CO2 monitoring is a valuable parameter. The advantage of PreSens is that this parameter does not exist in isolation, but can be incorporated into its multi parameter platform for linkage analysis with oxygen and pH.

4、 Multi parameter online monitoring system

If the customer's needs are no longer limited to a single parameter, but rather desire to simultaneously obtain data such as oxygen, pH, CO2, biomass, and even OUR, then PreSens's multi parameter system would be more suitable. Its multi parameter module includes SDR SensorDish Reader, SFR Shake Flask Reader, SFR vario, MCR-O1P1C1 and other solutions, which can achieve parallel monitoring for porous plates, shake flasks, culture tubes, cell culture flasks, and small biological reaction systems.

Among them, the SDR SensorDish Reader is suitable for non-invasive monitoring of O2 and pH in high-throughput culture containers such as 6-well and 24 well plates; SFR/SFR vario is more suitable for shake flask cultivation process, which can simultaneously monitor parameters such as oxygen, OUR, pH, biomass, etc., and can be directly put into the shake flask incubator for work; MCR-O1P1C1 is a multi parameter device that integrates O2, pH, and CO2 channels, suitable for desktop multi parameter monitoring. The advantages of such systems are very obvious for medium screening, process optimization, drug screening, strain evaluation, and pre scale-up research.

5、 VisiSens 2D Imaging System

PreSens also has a very distinctive feature, which is the VisiSens 2D imaging system. This type of system does not perform single point measurement, but combines luminescent sensing film and two-dimensional readout technology to observe the spatial distribution of O2, pH, and CO2 on the surface or local area of the sample. Common representative devices include VisiSens A1 and VisiSens TD. This type of system can record over 100000 measurement points in a single image, making it suitable for studying metabolic gradients, diffusion processes, internal heterogeneity of samples, and spatiotemporal changes.

This type of product is particularly suitable for microfluidic, tissue engineering, tumor microenvironment, material diffusion, surface reactions, cellular metabolic distribution, and complex heterogeneous system research. For the "spatial distribution problem" that ordinary instruments cannot solve, VisiSens provides another dimension of measurement capability.

6、 OEM components and customized integration solutions

In addition to standard equipment, PreSens also offers mature OEM components and engineering integration solutions. Its OEM segment covers optical measurement components for O2, pH, CO2, and biomass, including electro-optical modules suitable for monitoring and control system integration, as well as sensor structures and packaging forms that can be adjusted according to application scenarios. This section is very valuable for medical equipment, process control equipment, disposable systems, customized monitoring units, and customer owned instrument development projects.

If the customer is already an equipment manufacturer or has a need to embed oxygen, pH, CO2 optical detection modules into their own system, then PreSens is not just a brand that sells instruments, but also a technology platform that can provide underlying sensing solutions and module level support.

7、 Software, Accessories, and System Expansion

The equipment system of PreSens does not operate in isolation. Its supporting software module can be used for device control, data recording, image processing, and multi device networked measurement control; Some products support managing multiple instruments on one computer at the same time, as well as software modules for specific systems. For users who need to establish continuous monitoring networks, long-term record databases, or synchronize data collection across multiple devices, this supporting capability is crucial.

Main application directions suitable for the Chinese market

From the demand in the Chinese market, products like PreSens are very suitable for the following types of users:

The first category includes users of cell culture, microbial culture, and biotechnology development. These types of customers usually hope to continuously monitor key parameters such as oxygen, pH, CO2, biomass, etc. without interrupting the cultivation process, for optimizing cultivation conditions, process amplification, and data tracking. SFR vario, SDR SensorDish Reader, pH/oxygen sensing patches, and multi parameter systems are all suitable for this direction.

The second category is users of life sciences, medical research, and microenvironment analysis. Such applications typically require smaller scale and lower disturbance measurement methods, such as microfluidics, tissue engineering, tumor research, organ chips, animal and plant physiology, local metabolic gradient analysis, etc. Micro oxygen sensors, CO2 probes, VisiSens imaging systems, and OEM components will have more advantages in these scenarios.

The third category is users who evaluate the barrier properties of food and beverage, packaging, and materials. Oxygen is a crucial indicator in packaging sealing, top air analysis, material permeability testing, and shelf life research, Fibox 4 trace、 Trace oxygen sensors and accompanying flow/packaging testing solutions are more suitable for this direction.

The fourth category is users of environmental and industrial technology applications. For example, for sediment, soil, natural water bodies, pipeline oxygen monitoring, welding protection gas, process gas and liquid oxygen analysis, commonly used are immersion probes, flow tanks, portable oxygen meters and micro profiling systems.

Typical application areas

German PreSens oxygen sensorThe scope of application is relatively wide, with key industries including biological and environmental research, medical and life sciences, food and beverage, industrial and technological applications, biotechnology&Pharma, etc. Common practical application scenarios include cell culture and microbial culture monitoring, disposable bioreactor monitoring, shake flask culture, microfluidic research, tissue engineering, packaging oxygen detection, liquid and gas oxygen monitoring, packaging sealing evaluation, product shelf life research, and environmental sample analysis.