FL series dynamic axial compression chromatography column (DAC)

FL series dynamic axial compression chromatography column (DAC)

DAC dynamic axial pressurization technology, with fast and smooth piston lifting and lowering, good stabilizing effect and long stabilizing time, avoids the collapse of the inlet end to form a cavity and cause strong local convection and sample diffusion of the liquid inside the cavity,Very goodThe design of the piston and column bottom structure ensures a more uniform distribution of the column bed, allowing the column efficiency to remain stable for a long time.

FL series dynamic axial compression chromatography column (DAC)Structure and components:

The quality of the sealing structure of the piston sieve plate directly affects the performance of column efficiency and separation degree. Poor installation and sealing of the sieve plate can result in the packing in the homogenate liquid being flushed back into the distributor from the joint between the sieve plate and the seal during the column installation process. The FL series products have a reasonable structural design, which ensures that even if the diameter is large, the surrounding and central areas can be compacted to better ensure column efficiency. The following figure shows the distribution form and structure of the piston and column bottom.

By adopting precision mechanical polishing and electropolishing techniques as well as cylindrical technology, the pipe wall effect during column installation and use is minimized to the greatest extent possible, avoiding the occurrence of groove flow and complying with GMP and FDA regulations.

Sealing ring and liquid distribution system:

Imported spring energy storage sealing rings and sealing rings for sieve plates can be used for a long time and reduce the amount of consumables used. The high-pressure sealing ring uses OmniSeal spring energy storage sealing ring from SAINT-GOBAIN brand. A pressure assisted sealing device with a PTFE jacket, specially equipped with a corrosion-resistant metal energy storage spring. The spring is compressed, causing the lip of the jacket to tightly adhere to the sealing groove, thereby forming a seal.

especiallyThe design of the liquid distribution system ensures a good unity of column efficiency, column pressure, and symmetry, with better reproducibility.

Electric pneumatic parallel power source:

The filling time of the large preparation column packing mainly includes the transportation time of the homogenate and the time for the column bed to be compacted to the set pressure value. Most similar products take more than 12 minutes, indirectly affecting the separation effect. The FL series products adopt a power source output mode of electric and pneumatic parallel connection, which has more stable mechanical performance and further shortens the column installation time, avoiding the collapse of the inlet end to form a cavity and causing strong local convection and sample diffusion of the liquid in the cavity, keeping the column efficiency stable for a long time and avoiding column efficiency loss; The fastest loading can be controlled within 5 minutes. The dynamic source part adopts the brand Haskel pneumatic liquid pump, which is composed of three parts: gas driven part, hydraulic part, and directional control valve. The piston of the gas driven part and the plunger of the hydraulic part are connected together and controlled by a directional valve to automatically perform reciprocating motion. By using a large area piston and a small area plunger, the pressure of the driving gas acting on the piston is transmitted to the plunger, thereby increasing the outlet pressure of the liquid. And the hydraulic cylinder guide sleeve is not leaking, which can prevent rusting.

FL series dynamic axial compression chromatography column (DAC) parameters:

FL series ordering information: