Evaporative light detector

CADetector a1Evaporative light detectorIt is a universal detector with high sensitivity, high reproducibility, and wide linear range, capable of detecting non-volatile and semi volatile substances, and can be accurately used for quantitative or semi quantitative analysis. The CA detector does not rely on compounds having UV absorption, fluorescence, or electroactive groups. Compounds separated by HPLC, UPLC, or SFC can generally be detected, making the CA detector an ideal detector for various laboratories.

Principle Introduction:

The liquid chromatography eluent reaches the detector inlet and mixes with nitrogen gas in the atomizer to form an aerosol. The large mist droplets are diverted in a designed splitter, while the small mist droplets enter the drift tube under the push of nitrogen gas and evaporate the mobile phase to obtain solute particles (analytes); At the same time, nitrogen gas is used as the charging gas to charge the solute particles. Finally, a high-sensitivity charge trap is used to capture and record the electrical signal, resulting in a chromatogram.

Specialized in Li Technology：

CADetector a1Evaporative light detectorUsing self-developed specialized Li technology to optimize the charged ability of aerosol particles.

performance advantage：

High sensitivity, providing excellent response for compounds as low as pg level.

High repeatability, with RSD below 2%, will provide you with reliable and accurate experimental results.

Wide linear range, with a linear range of 4 orders of magnitude, eliminating the need for tedious logarithmic calculations.

Wide applicability, flexible response to non-volatile and semi volatile substance detection.

More consistent, CA detector is a quality based detector that can more accurately reflect the actual mass of a substance than other detectors.

The quantitative basis of CA detector is that the peak area is related to the surface charge of the analyte particles, and the surface charge of the analyte particles is related to the mass of the analyte.

The CA detector is based on a new design principle, which solves some limitations in the design and principle of other detectors, achieves universality, and can provide consistent response to non-volatile compounds. At the same time, it can achieve high sensitivity and low detection limit, and easily detect compounds in the order of ng.

Advantages of CA detector compared to other LC detectors：

Compared with UV absorption detectors and fluorescence detectors, the electric sol detector has excellent universality and higher sensitivity than differential refractive index detectors and evaporative light scattering detectors. At the same time, it can detect non ionizable substances more easily than mass spectrometry detectors, and is complementary to the qualitative ability of mass spectrometry detectors.

Compared with evaporative light scattering detectors, CA detectors have higher detection sensitivity, better intra - and inter day repeatability, and a wider linear range. Many impurities that cannot be detected by evaporative light scattering detectors have good response on CA detectors.

The CA detector response of difficult to volatile compounds is independent of the physicochemical properties of the analyte. In the case where the composition of the mobile phase entering the CA detector remains unchanged, different compounds with the same injection volume have the same CA detector response. In other words, the CA detector can quantify unknown compounds using linear curves of known compounds. In addition, the data obtained from compound purity analysis using CA detector is closer to the true composition of the sample.

Application Examples：

CA detectors are widely used and can play a huge role in fields such as biomedicine, food and beverage, environmental monitoring, petrochemicals, semiconductor chips, and new energy.

CAD standards：