Chiral HPLC Columns

Chiral chromatographic column, chiral preparation chromatographic columnIt is a chiral stationary phase made by fixing monomers with optical activity on silica gel or other polymers. By introducing a chiral environment to present physical differences between enantiomers, the goal of optical isomer separation can be achieved. To achieve chiral recognition, there are at least three types of interactions between chiral compound molecules and chiral stationary phases. This type of interaction includes hydrogen bonding, even to even interactions, π - π interactions, electrostatic interactions, hydrophobic interactions, or spatial interactions. The chiral separation effect is the result of multiple interactions working together. These interactions alter the chiral separation results by affecting the formation of embedded complexes, the bonding of specific sites with analytes, and so on. Due to the weak force, it is necessary to carefully adjust and optimize the mobile phase and temperature to achieve good separation effect.

Shansa (Shanghai) Industrial Co., Ltd. was established in 2016, mainly engaged in the development and manufacturing of chromatographic loading systems and hardware for preparing chromatographic columns, while also providing corresponding chromatographic separation technology services and consulting. With over years of experience in first-line chromatographic separation and services, our products strive to provide chromatographic separation scientists with products that meet their needs from the beginning. This breaks the disconnect between chromatographic separation column hardware providers and front-line users in the market, and close communication enables our products to constantly optimize and improve for higher cost-effectiveness and more convenient operability.

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