Guanya brandGel water activity meterBrands and verification regulations are widely used for activity test of gel, freeze-dried powder, lotion, spray, cosmetics, oral liquid preparation, cream, ointment, aerosol, patch, capsule, patch, tablet, powder, pill, solution, mixture, syrup, tincture, liniment, suppository, film, powder, extract and other samples.

about2025Interpretation of Water Activity in the Chinese Pharmacopoeia

2025The Chinese Pharmacopoeia specifies water activity（Aw）As a key parameter for microbial control of non sterile drugs, its value ranges from0～1Reflect the energy state of water in the sample and the degree of binding with its components. ‌

Definition and function of water activity

Water activity refers to the ratio of the vapor pressure of sample water to that of pure water, used to evaluate the activity state of water in drugs. For example, when the moisture content of a drug increases, the water activity may sharply increase. The risk of microbial contamination in non sterile drugs is directly related to water activity, and reducing its value can inhibit microbial reproduction and extend shelf life. ‌

Testing methods and instruments

Determine water activity by measuring the ratio of sample vapor pressure to pure water vapor pressure in a closed space. Shenzhen Guanya Technology Co., Ltd. produces various types of water activity meters: handheld, desktop, temperature controlled water activity meters, which can quickly detect the water activity of non sterile drugs and meet the requirements2025Pharmacopoeia Version9211The guiding principles require, Meet the needs of different customers.

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Relationship with Microbial Control

Different microbial populations require different levels of water activity (such as spores, Salmonella, etc., which have higher tolerance). When the actual water activity of the drug is lower than the required value for microbial growth, there may still be residual tolerant microorganisms. Therefore, it is necessary to combine microbial limit testing and packaging material evaluation to comprehensively control quality. ‌

Water Activity: A New Perspective on Microbial Control of Drugs

In drug production, water activity is a often overlooked but crucial parameter. Water content and water activity are two completely different concepts. The former refers to the proportion of water in dry or wet matter, while the latter refers to the amount of free water in the product, which is the basic data for enzyme and microbial growth.

Definition of water activity:The ratio of the vapor pressure of water in a solution or food at a certain temperature to the vapor pressure of pure water at the same temperature. This ratio reflects the effective water that microorganisms can utilize and the stability of the product.

Assess microbial risk:By measuring water activity, it is possible to predict microbial issues that drugs may encounter during production, storage, and use.

Controlling microbial growth: By adjusting the water activity of drugs, the growth of microorganisms can be effectively controlled, thereby improving the stability and safety of drugs.

Research on Water Migration:The migration of water in drugs is also an important factor affecting drug stability, and this process can be monitored by measuring water activity.

Manufacturer:

Shenzhen Guanya Moisture Meter Technology Co., Ltd./Shenzhen Guanya Technology Co., Ltd

Guanya brandGel water activity meterProduct Introduction

The water activity meter developed by Shenzhen Guanya adopts multiple analysis and testing modes7A high-resolution LCD screen with full touch operation mode, which can display real-time data changes of sample temperature, activity value curve, activity value, temperature and other parameters during the analysis process. The entire testing process is fully automated, and after analysis, an automatic voice alarm is triggered. The instrument screen automatically locks the final data and stores the test data at the same time. No need for personnel to supervise or maintain the experimental process. After the experiment is completed, a dedicated micro printer will print out the detected valid data in real time for long-term preservation. You can also view and print historical test records in the history section.

The equipment is professionally designed with stable performance, high detection accuracy, short measurement time, and easy operation. By touching the color screen display, the screen backlight brightness can be set, achieving a friendly human-computer interaction interface. Multiple channels can be opened simultaneously to measure, measure or calibrate time10About minutes, the time can be set according to different tested objects. Long calibration cycle, no need for frequent calibration. Simultaneously equipped with print output function, curve drawing function, and upper computer data acquisition system. It can facilitate data recording and collection, which can be used for later data comparison and analysis.

Guanya brandGel water activity metertechnical indicators

1. Activity testing range:0.000-1aw

2. Resolution:0.001AW

3. Test channel:1-4(Optional, regular single channel), please consult sales for different prices;

4. Temperature resolution:0.1℃

5. Sample name: editable, input sample name

6. Test modes: Multiple

7. Screen brightness: adjustable screen brightness

8. Time: Adjustable

9. Security feature: Operator password/Administrator password setting function

10. Dual calibration function: multi-point calibration of saturated salt solution, calibrating equipment temperature based on room temperature

11. Data storage: automatic storage

12. History: View history records

13. Voice broadcasting: built-in

14. Printing function: The micro printer can print data at any time

15. Test interface display: sample name, temperature curve, activity curve, temperature value, activity value, test mode

16. Factory reset: equipped with

17. Working environment: Temperature0～50℃humidity0～95%RH

18. Supply voltage: AC220V

19. Overall dimensions:280mm×226mm×120mm

Other products

Shenzhen Guanya Company also produces various rapid moisture meters (drying method, chemical method, card furnace method)pHAnalytical instruments, density meters (solid, particle, powder, etc.), grain bulk density and other products are welcome to inquire.‌

Gel water activity meterBrand and Verification Regulations