Body composition analysis of DXA animal bone density

DXA animal bone density body composition analysis (animal bone density measurement) is the gold standard for animal bone density analysis. The measurement process involves absorbing and filtering the X-rays released from the X-ray tube, dividing them into high and low energy X-rays. Based on the attenuation and absorption differences of photons of two different energies passing through the human bones, the content of body fat and bone minerals is obtained through computer processing to determine BMC, BMD, and fat content data.

Advantages of DXA

DXA analysis is based on clear image quality, ensuring the accuracy and reliability of measurement results, and is the gold standard for bone density measurement. Through attenuation calibration, it ensures the accuracy of fat content.

The dual energy X-ray absorptiometry method is an analysis and calculation of animal bone density (BMD) and body composition (BMC, Fat, Lean) based on ultra-high resolution digital image analysis. The KUBTEC animal bone density and body composition analysis system uses real-time high-resolution digital images combined with high-quality body composition analysis software to achieve the dual energy X-ray absorptiometry method (the gold standard of the World Health Organization). Without the need for dissection, high-quality live X-ray imaging can be completed through the provided anesthesia interface to analyze the bone density and body composition (BMC, Fat, Lean) of living experimental animals.

Generally, chemical analysis of animals takes one hour (homogenization, scraping, cleaning, weighing, drying, chemical extraction, etc.), while drying or ashing of chemical extraction takes several days. KUBTEC can analyze bones and body composition in just 30 seconds to obtain results. Since there is no need to dissect experimental animals and conduct each series of evaluations, it can reduce the consumption of 500 to 800 animals per year, saving a lot of money.

KUBTEC Animal Bone Density and Body Composition Analysis System

Characteristics of DXA Animal Bone Density Body Composition Analysis System:

1. High resolution: Provides 10LP/mm high resolution and high-speed imaging, with low animal dose rates, reducing the impact on experiments to a minimum.

2. High speed imaging and analysis: With simple anesthesia, experimental animal bone density and body composition (BMC, Fat, Lean) analysis data can be obtained from KUBTEC high-resolution images within 19 seconds

3. It can provide HD CCD to form high-resolution white light imaging, combined with KUBTEC Blender function, to complete color/X-ray/body composition area delineation/data analysis mutual verification function.

4. Adopting X-ray cone imaging will not cause result deviation due to different animal placement positions.

5. Multi functional imaging: can freely switch between high-resolution X-ray imaging, single energy X-ray analysis and dual energy X-ray analysis functions

6. Large field of view (FOV): The scanning range (basic: 120mm × 150mm, optional: 230mm × 290mm) can analyze the bone density and mineral content, fat and lean meat of small animals such as mice, rats and medium-sized animals such as dogs, cats, rabbits and guinea pigs. The large field of view combined with cone X-ray scanning has no limit on animal weight.

7. Animals receiving low-dose irradiation: KUBTEC ensures high resolution while ensuring that animals receive low-dose radiation, allowing them to scan multiple times over a period of time and dynamically analyze and evaluate body composition.

8. Safe and reliable, without radiation hazards: KUBTEC's multiple chain technology and lead glass isolation device can effectively block radiation, ensuring that the surface dose of the equipment is lower than the environmental background and protecting researchers.

9. Accurate and reliable data: The measurement results are accurate to 0.001g with an error of less than 1%

10. The analysis software has powerful functions and multiple data saving formats (such as CSV/Excel format) are easy to call.

11. Sample forgetting reminder function: If the sample is left in the warehouse for a long time without operation, the system will automatically warn and remind to take out the sample in a timely manner.

12. The data results can be directly input into Solidworks to form engineering drawings for direct 3D printing output.

13. Compliant with FDA standards, FDA filing number: 0610044-00

14. Equipped with a clear animal video selection tracking tool (optional)

KUBTECAnimal Bone Density and Body Composition Analysis System

Measurement indicators:

Small animal bone density value (BMD):

• Whole body bone density value Total BMD

• ROI area (user specific parts) bone density value ROI BMD

Body composition values of small animals (BMC, Fat, Lean)

• Whole body bone mass BMC

• Local bone mass ROI BMC

• Bone length, area, and volume

• Fat mass

• Fat percentage content

• Fat/tissue percentage

• Muscle mass

• Muscle percentage content

Based on a large amount of data samples, long-term sample curve fitting can be performed to evaluate the development trends of BMD, Fat, Lean, and other factors

Gender specific BMD, Fat, and Lean assessments can be conducted based on animal gender

KUBTEC Animal Bone Density and Body Composition Analysis System

Product Specifications
Detection method: Dual energy X-ray measurement method

Emission mode: switchable between single energy and dual energy X-ray imaging modes

Acquisition mode: fully automatic AEC acquisition or manual acquisition

Scanning method: Cone beam

Image resolution: 10.0LP/MM (48um pixel size)

Scanning area: 250 mm x 300 mm in size

Scanning time: Full body scanning time of 19 seconds

High accuracy: ≤ 1%

ROI region: Numerical analysis of 6 ROI regions, with the ROI portion automatically enlarged to form a picture in picture for easy analysis

Composition distribution: It can directly display the distribution map of various body components

Measurable targets: rats, mice, rabbits, chickens, fish and other animals, with no weight restrictions within the measurement area

Data output: result values and image conversion storage

Calibration function: Daily fully automatic calibration, zero preheating time

Safety protection: Fully enclosed lead protection, no additional protection is required for the room.

Picture in picture: Select detailed local areas of interest from bone, lean meat, and adipose tissue images, automatically enlarge the images for local comparison, and form a picture in picture for convenient DXA analysis.

Data can be imported into SolidWorks for reconstruction and 3D printing

Network remote connection access

KUBTEC Animal Bone Density and Body Composition Analysis System

Software Function Introduction:
DIGIMUS automatically calculates bone mineral density (BMD), bone mineral density (BMC), and percentages of lean tissue and adipose tissue for the whole body and lesion areas. The software automatically eliminates interference from surgical needles, metal ear tags, wound closure clips, or nasal cones, making it a bone density and body composition measurement system.

KUBTEC Animal Bone Density and Body Composition Analysis System
Customer Example:

National Institute of Cardiopulmonary and Hematology, Peter Borough Hospital of Hologic, Yale University School of Medicine, Harvard University School of Medicine, Baylor College of Medicine, NASA Aerospace Laboratory, Kunming Institute of Zoology, Wenzhou Medical University, etc

• Introduction to KUBTEC

• KUBTEC is a global manufacturer of medical and laboratory X-ray equipment, providing innovative tools for digital X-ray equipment in areas such as sample X-ray imaging, low-dose imaging, scientific research, forensic analysis, non-destructive testing, and X-ray irradiation. KUBTEC's products enable medical professionals to provide excellent quality of care for patients, while also providing high-performance laboratory X-ray equipment to support scientific research for laboratory researchers.

• KUBTEC provides a complete set of imaging solutions for breast radiologists, breast surgeons, clinical doctors and pathologists, as well as scientists and laboratories. KUBTEC's MOZART series provides intraoperative breast sample imaging using 3D tomographic tomography, which helps to preserve the breast to a large extent, while removing breast tumors with integrity, reducing the probability of reoperation after breast cancer resection by more than 50%.

• KUBTEC is the main developer of low-dose digital X-ray (DR) systems, and KUB 250 is truly portable, FDA approved for use in neonatal intensive care units (NICUs) as a low-dose digital X-ray system. It provides the world's highest resolution low-dose imaging system for newborns while reducing radiation dose by over 40%.

• KUBTEC's XPERT real-time sample X-ray imaging system provides clear imaging results, reduces processing time to make patients feel more comfortable, and supports bedside surgery.

• The XPERT/PARAMETER series digital X-ray radiology system (DR) can provide high-resolution, practical imaging systems, enhancing laboratory research and work efficiency. Widely used in specimen X-ray imaging, scientific research, forensic analysis, non-destructive testing, radiation biology and other fields.

• The XCELL series biological irradiation instrument is widely used in large laboratories and can provide customized services to meet different research needs.

• KUBTEC has obtained ISO 9001 and ISO 13485 certifications, and designs and manufactures equipment that meets radiation safety standards in major countries such as the United States, Canada, and Europe. It provides system manufacturing and training support in various regions.

• product line

• Digital X-ray machine

  1. High resolution small animal digital X-ray machine

  2. Animal Bone Density and Body Composition Analysis System - SXA&DXA

  3. Botany digital X-ray analysis system

  4. Digital autoradiography imaging system

  5.3D X-ray digital imaging system

  6. X-ray pathology analysis system

  7. X-ray forensic identification system

  8. X-ray non-destructive testing system

  X-ray irradiation instrument

  1. Desktop small sample biological X-ray irradiation instrument XCELL 50

  2. Desktop biological X-ray irradiation instrument XCELL 140

  3. Biological X-ray irradiation instrument XCELL 160

  4. Biological X-ray irradiation instrument XCELL 225

  5. Biological X-ray irradiation instrument XCELL 320

  6. Biological X-ray irradiation instrument XCELL 350

  7. X-ray diagnosis and treatment system

  Kubtec software package

  1. Kubtec DIGICO Universal Analysis Software Package

  2. Kubtec germplasm resource research software package

  3. Assistant imaging software package

  4. Kubtec DIGIMUS animal body composition analysis software package