Beijing Keyu Xingye TDCCS-3D Microgravity Simulator

NegotiableUpdate on 07/07

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Overview

The Beijing Keyu Xingye TDCCS-3D microgravity simulator is a novel low shear culture system designed for adherent and suspended cells. Based on existing domestic and foreign literature, it is clearly demonstrated that gravity has a significant impact on cell proliferation and differentiation. Cultivating cells in a micro heavy environment has shown significant improvements in both cell quality and passage quantity; However, due to the scarcity of space station resources and excessive cost investment, many scientific research ideas cannot be implemented; The TDCCS-3D series universal multi axis rotary system developed by Beijing Keyu Xingye Company is an experiment with a new concept

Product Details

Parabolic flight and tower descent are methods of creating microgravity environments on Earth, similar to the International Space Station (ISS) and China Space Station. However, whether it is parabolic flight or tower landing, they can only create a microgravity environment for a few seconds. In order to create a microgravity environment on Earth for a long time, scientists invented the "inclinometer" in the late 19th century, initially to study the response of plants to gravity. “The inclinometer "is a horizontally rotating machine that fixes the sample on a machine that rotates around a horizontal axis to suppress unidirectional gravity loads. This is the original 1-axis (1D) inclinometer, which allowed researchers to study the effects of gravity in ground-based laboratories for a long time, but it could not create a microgravity environment. Therefore, the 3D inclinometer was born. The 3D inclinometer has two rotation axes, which can achieve three-dimensional rotation; Allow unidirectional gravity to disperse in different directions to create a simulated microgravity environment.Beijing Keyu Xingye TDCCS-3D Microgravity Simulatoremerge as the times require.

Beijing Keyu Xingye TDCCS-3D Microgravity SimulatorBreaking through traditional structural design, a tilted 45 ° rotating device is used to achieve three-dimensional rotation of the entire machine, and low shear force is also achieved in the cell culture process. The TDCCS-3D microgravity 3D cell culture system also adds the function of "overweight", which is an intelligent 3D cell culture system that integrates both microgravity and supergravity modes. The overweight mode cell culture function of TDCCS-3D can promote cell differentiation; Can meet the experimental needs of researchers exploring the physicochemical properties of cells in overweight environments.

北京科誉兴业TDCCS-3D微重力模拟仪

Application areas and breakthrough progress:

1. Biomedical research

-Tumor model: 3D tumor spheres better simulate the tumor microenvironment for studying invasion, metastasis, and drug resistance mechanisms.

-Neurodegenerative diseases: constructing brain organoids and studying the pathological processes of Alzheimer's disease and Parkinson's disease.

2. Drug screening and toxicity testing

-3D cultured cells exhibit drug responses that are closer to clinical outcomes, reducing dependence on animal experiments.

-Case: In liver toxicity testing, the metabolic activity of 3D liver cell models is more than 5 times higher than that of 2D cultures.

3. Regenerative Medicine and Tissue Engineering

-Combining stem cell technology to generate functional tissues (such as myocardium and cartilage) for transplantation and repair.

-The ability of angiogenesis is significantly enhanced in microgravity environment, promoting the construction of complex organs.

4. Space biology research

-Study the changes in cellular behavior during long-term space flight, such as bone loss and immune suppression.

-Provide a basis for ensuring the health of astronauts in future deep space exploration.