Bacterial endotoxin analyzer

Bacterial endotoxin analyzer

I. Overview

According to the "Bacterial Endotoxin Test Method" in the Chinese Pharmacopoeia, based on the gel method, it adopts a water bath constant temperature mode, a 7-inch touch screen, and has a timing reminder function.

Applicable to: monitoring of bacterial endotoxin contamination points in drugs and intermediate products of pharmaceutical companies that require bacterial endotoxin testing, verification and daily monitoring of injection water, bacterial endotoxin testing of medical devices, testing of bacterial endotoxins in clinical drug injection mixtures, testing of bacterial endotoxins in water and food, and other bacterial endotoxin testing scenarios.

2、 Main functions

1. Adopting a water bath constant temperature control method, it can remember preset temperature values for easy use;

2. Adopting a 7-inch touch screen design, the operation is convenient and intuitive;

3. When the preset time expires, it has a timed reminder function;

4. Built in water bath circulation device to ensure uniform temperature of the water bath;

5. Specially made high-quality silicone test tube sleeve ensures that the test tube is centered and stable, and does not fall off when flipped over.

3、 Main performance indicators

1. Default parameters: 37 ℃, 60 minutes; It can also be set as needed, with a temperature range of room temperature to 50 ℃

2. Temperature control accuracy of water bath: 37 ± 0.2 ℃

3. Timing accuracy: 60 minutes ± 45 seconds

4. Test tube hole position: 60

5. Test tube size: ф 10 * 75mm

6. Continuous working hours: 24 hours

7. Power supply: 220V/300W

4、 Instrument structure

5、 Installation method

1. Open the packaging box and check the type and quantity of attachments according to the packing list.

2. Remove the packaging and fasteners.

3. After filling the water bath with clean water, turn on the power to start using it.

(Turning on the circulating air pump can make the temperature inside the water bath more uniform)

6、 Usage method

1. Power on: The power switch is located on the right rear side of the instrument, and the circulation air pump switch is located on the left rear side.

After turning on the power switch, the instrument is powered on and the display screen shows the startup screen after loading the system:

2. After starting the screen, automatically jump to the main interface:

3. Operation

On the right side of the page is the button area

1) Parameter settings:

Click the "Parameter Settings" button to jump to the parameter input interface

On this interface, you can set the "set temperature" and "experiment duration" (the factory default settings are 37 ℃ and 60 minutes).

Click on the item box that needs to be modified, and the soft keyboard will pop up. Modify the parameters through the soft keyboard, and press the Enter key on the soft keyboard after modification, and the soft keyboard will disappear.

After all parameters are modified, press the "confirm" button to make the modified parameters effective and return to the main interface.

2) Heating up

Click the "Heating Stop" button on the right side of the main interface, which will change to "Heating On". At this point, the instrument will start heating according to the set temperature and automatically enter a constant temperature state.

The real-time temperature will be displayed in the "Real time Temperature" box above the main interface. After the temperature reaches the set temperature and remains constant for a period of time, the experiment can begin.

3) Experiment begins

Click the "Experiment Stop" button on the right side of the main interface, which will change to "Experiment Start". At this time, the instrument enters the timing state, and the timer starts in the "Running Time" box, displaying the running time. When there are still 30 seconds left before the set duration, the instrument will emit a beep sound. After reaching the set duration, a prompt box will pop up.

4) Experiment pause (stopped midway through the experiment)

During the experiment, if it is necessary to pause:

You can press the "Experiment Start" button to jump to the prompt interface, and the timer will pause. When you need to continue the experiment, press the "No" button to close the prompt interface and the timer will continue to run.

Stop halfway through the experiment:

You can press the "Experiment Start" button to jump to the prompt interface. Press the "Yes" button to close the prompt interface, the timer stops running, and the experiment stops.

4. Temperature calibrationBacterial endotoxin analyzer

Due to the physical characteristics of temperature drift in temperature measuring components, the instrument may experience temperature deviation exceeding the standard after a period of use. In this case, it is necessary to calibrate the instrument temperature. The method is as follows:

8) Set the instrument temperature to 37.0 ℃; Open the instrument circulation air pump; Start heating, wait for the temperature to reach the set temperature, and keep it constant for half an hour. Take a calibrated precision mercury thermometer, insert it into the water bath, and make the measuring head of the mercury thermometer as close as possible to the temperature sensor of the instrument. After the reading stabilizes, accurately read the displayed temperature (including one decimal place);

9) After clicking the "Temperature Calibration" button on the right side of the main interface, the "Temperature Calibration" interface will pop up. Accurately fill in the displayed temperature of the mercury thermometer (including one decimal place) in the "Actual Temperature" box.

Click the "Confirm" button to activate the calibration, close the calibration interface, and return to the main interface. At this point, the temperature inside the measured temperature box begins to change. After about three to four seconds, the temperature value inside the measured temperature box will become the temperature value indicated by the mercury thermometer (in this case, there is a normal error of 0.2 ℃ between the corrected measured temperature value and the mercury thermometer reading. The local heating system algorithm controls the fluctuations in advance, and after a period of heating and constant temperature process, the system will automatically compensate).