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Nanjing Kebai Biotechnology Co., Ltd
BCRP MDA-MB-468
NegotiableUpdate on 05/06
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Overview
BCRP MDA-MB-468
Product Details
BCRP MDA-MB-468
| I. Background | |
BCRP（乳腺癌耐药蛋白，Breast Cancer Resistance Protein），编码基因为 ABCG2，属 于 ATP 结合盒（ABC）转运蛋白家族 G 亚家族，是一种 ATP 依赖性跨膜外排转运蛋白。 其广泛分布于正常组织如肠道、肝脏、肾脏、血脑屏障、胎盘及肿瘤细胞，主要功能为通 过 ATP 水解主动外排外源性毒物、代谢物及药物，参与解毒、药物代谢调控及屏障保 护（如血脑屏障、胎盘屏障）。 | |
| II. Description | |
BCRP MDA-MB-468细胞，在MDA-MB-468细胞的基础上，稳定表达人 BCRP。 | |
| III. Introduction | |
| Expressed gene: | BCRP |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+ 10% FBS+ 2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| IV. Representative Data | |
Figure 1. WB of BCRP MDA-MB-468. | |
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