Activotec peptide synthesizer/fully automatic

Activotec peptide synthesizer/automaticProduct Description:

(1) Main functions

*High quality peptides

*Any scale from 0.005 to 5.0 millimoles

*Easy to use; Define your own protocol or use peptide wizard software

*Perform any Fmoc or t-Boc chemistry

*Compatible with green chemical solvents

*PNA synthesis

*Safe to use, instrument enclosed

*Fully automatic, unlimited number of amino acids

*Disposable reactors and amino acid containers

*Using commercial amino acids, resins, and reagents

*Use fluid sensors for self diagnosis, checking reagent delivery, emptying, and transfer

(2) Usability

*Very user-friendly software; Enter the sequence, fill in the quantity and resin specifications, and then proceed to run

*The software generated worksheet tells users what to prepare

*Chemistry, Free Choice for the Present and Future

*Disposable reactors and amino acid containers

*60 amino acid containers, unlimited quantity added

*Closed cabinet for safe desktop use

*Each synthesized log file

*Easy to cut or transfer disposable reactors to Activo-P12 cracking equipment on the machine

(3) High quality peptides

*In the entire inert atmosphere

*Accurate and rapid reagent delivery and cleaning

*Efficient Reverse Mixing

*Bottom filtration of disposable reactor

*Fresh amino acids in powder

*Pre activated container

*Multi tasking processing

*Heating reactor

*UV monitoring

(4) Chemistry

*Fmoc or t-Boc Fmoc or t-Boc

*PNA synthesis

*In situ or pre activated

*Use any coupling agent; HBTU, HCTU, HATU, TBTU, PyBOP, DIC, etc

*Use any coupling agent; HBTU, HCTU, HATU, TBTU, PyBOP, DIC, etc

*Hardware and software compatible with green chemistry

*Use any resin; Polystyrene or PEG based scaffolds

*Use any protocol

*Synthesize peptides of any length

(5) Reagent

*9 reagent/solvent pipelines

*250 milliliters to 19 liter options

*Allow unmanned operation

*By filling cycles or timed delivery

*Accurate addition

*No calibration required

*Independent jet of piperidine/TFA

Activotec peptide synthesizer/automaticThe configuration system includes:

*An automated peptide synthesizer suitable for peptide and organic solid-phase synthesis.

*Any Fmoc or Boc coupling strategy can be used.

*The synthesis scale ranges from 0.05 millimoles to 5.0 millimoles.

*The area in contact with the reactants is chemically inert.

*Having an inert atmosphere.

*Provide disposable reactor containers, 5 10 milliliters and 5 40 milliliters.

*Reactor heating options for precise heating when needed.

*UV monitoring option with feedback control.

*Pre activated containers allow for scaling up and increased flexibility in chemical protocols. The standard is 30 milliliters, but 75 milliliters can also be provided.

*Amino acids are arranged in a rotating disk with 60 positions for 15 milliliter Falcon tubes. Provide a 30ml Falcon tube bracket for easy scaling up. The synthesizer is designed to use dry amino acids in each coupling cycle, but the software can choose to use pre solution liquid amino acids (if needed).

*The synthesis scale can be adjusted for each amino acid in the sequence.

*If necessary, the chemical protocol can be modified for each amino acid in the sequence.

*9 reagent bottles, standard GL45 thread, capacity adjustable, but can range from 250 milliliters to 19 liters (for DMF). Reagent bottle 9 is isolated from other reagent bottles and used for TFA or piperidine. Amino acid containers can be used as reagent containers when small volume is required to minimize the dead volume of expensive reagents.

*Super center wrist movement hybrid system. Users can change the mixing speed and angle.

*All key components involved in the synthesis process, such as amino acid dissolution and reagent addition, are clearly visible to users.

*The system is enclosed and designed for safe use on the workbench, and is equipped with an exhaust fan accessory. This means that users can avoid contact with any chemical gases, and the synthesizer does not need to be placed in a fume hood.

New automatic peptide synthesis and UV monitoring.

The mature function of Activo-P11 peptide synthesizer enables precise automatic UV monitoring of Fmoc removal during solid-phase synthesis by providing feedback to the synthesizer software.

This allows users to monitor the peptide synthesis process and automatically change the deprotection and conjugation scheme for each amino acid based on the results.

P11 is a peptide synthesizer that uses online UV feedback to control coupling time, repeat deprotection, temperature, and coupling times. This improves the purity of all sequences and reduces synthesis costs, while avoiding unnecessary heating or double coupling of unwanted amino acids.

ActivoPep-Software-Release.pdf。

This enables P11 users to synthesize longer and more complex peptides and gain detailed information on the conditions required to couple individual amino acids.