3D cell culture organ chip organoids

1、 What is 3D cultivation?

3D cell culture organ chip organoidsUnlike traditional 2D cultivation, 3D cultivation technology refers to the cultivation of cells or tissues in a 3D environment, which can better simulate the growth mode of cells in vivo, because cells can interact more naturally with surrounding cells and matrix in a 3D environment, thus simulating the behavior of cells in the human body environment more realistically in vitro.

2、 Application areas based on 3D cultivation technology

The application scenarios and purposes of 3D culture technology are similar to 2D cell culture, and are currently being applied in drug discovery, personalized therapy, and other fields based on organoids, microfluidic organ chips, bioprinting, and other forms. The following are several related concepts（3D cell culture organ chip organoids）：

Organoids: A concept in developmental biology that induces differentiation of stem cells or organ progenitor cells using 3D culture techniques in vitro to form three-dimensional cell complexes that are structurally and functionally similar to the target organ or tissue. These complexes can mimic the interactions, anatomical, and even functional features between cells and matrix in real organs.

Organ on chips (OOC): Human microphysiological systems on microfluidic chips, composed of controllable miniaturized physiological environments (Microphysiological systems, MPS), containing one or more tissue specific functional units. The purpose is to more accurately replicate human physiology in vitro and quickly obtain transformation related data after administration for evaluating the efficacy of human drug delivery.

Bioprinting is a process of using 3D printing technology to generate living tissues or organs with complex structures.

Next, you can visit the Manbo Biotechnology website to obtain our "Integrated Solution Brochure for Organoid Chips"

On the other hand, in the process of deepening the cultivation of organoid and organ chip products, we have observed that many research partners, although possessing cutting-edge research directions and innovative goals, face dual challenges in technology implementation, either due to a lack of practical experience in complex organoid cultivation and chip modeling techniques, or limited by objective conditions such as experimental equipment and personnel configuration, making it difficult to transform high-quality products into concrete research results.

To this end, we have partnered with domestic providers of organoid solutions to officially launch a "product+service" dual wheel drive model, breaking down technical barriers and building a direct bridge from "ideas" to "achievements" for you.

Shanghai Manbo Biotechnology specializes in organoids and organ-on-a-chip technology, providing complete organoid/organ-on-a-chip solutions to assist in scientific research and drug development.