The industry standard for the determination of Diazepam and its metabolites in aquaculture environments (water bodies, sediment) has been released

On April 27, 2025, the Ministry of Agriculture and Rural Affairs officially released the industry standard SCT 9453-2025 "Aquaculture Environment (Water Bodies, Sediments)DiazepamDetermination of its metabolites by liquid chromatography tandem mass spectrometry. This standard was jointly drafted by multiple member units of the Industry Education Integration Community in the food safety industry, including the South China Sea Fisheries Research Institute of the Chinese Academy of Fishery Sciences and Guangdong Zhongjian Dayuan Testing Technology Co., LtdGuangdong Dayuan Oasis Food Safety Technology Co., Ltd., etc. The standard is applicable to aquaculture environmentsIn water bodies and sedimentDiazepamDetermination of residual amount. This standard will be officially implemented on August 1, 2025, providing a key technical basis for environmental monitoring in aquaculture.

Diazepam is a common psychotropic drug that is sometimes illegally used in aquatic transportation to reduce fish stress reactions due to its sedative effect. However, the residues of the drug and its metabolites in the environment may have long-term negative impacts on aquatic ecosystems and ultimately threaten food safety and consumer health through bioaccumulation. For a long time, effective regulation of this type of pollutant has been difficult due to the lack of high-throughput and high-sensitivity standard detection methods.

thatThe standard is based on high-performance liquid chromatography-LC-MS/MS technology is used to determine the composition of aquaculture water and sediment samplesDetection method for residual levels of Diazepam and its three main metabolites. The standard defines key technical indicators such as detection limit, quantification limit, precision, and recovery rate of the method in detail, and is applicable to environmental monitoring, risk assessment, and daily supervision work.

The introduction of this standard is of great significance in improving the quality and safety level of aquatic products and promoting the green and healthy development of the aquaculture industry.