Ruishi Technology releases full chain animal imaging and biological irradiation products

Ruishi Technology releases full chain animal imaging and biological irradiation product matrix: empowering Chinese scientific research with independent innovation and cracking scientific research instrumentsThe bottleneck of the device

In the field of basic scientific research, research instruments are the core driving force of original innovation. For a long time, Chinese universities and research institutions have heavily relied on imported equipment in key fields such as CT imaging, optical imaging, and precision irradiation (radiotherapy), posing severe challenges to their research autonomy. In recent years, with the intensification of international technological restrictions, the export of some scientific research instruments has been restricted, resulting in the obstruction of domestic scientific research projects and the forced shift of research topics. The urgency of domestic substitution has become increasingly prominent.

Faced with this situation, national policies continue to intensify. In 2022, the fiscal subsidy policy will promote the upgrading of equipment in universities. In 2024, the "Action Plan for Promoting Large scale Equipment Upgrading and Consumer Goods Trade in" will clearly list scientific research instruments as a key area, opening up a broad market for domestic equipment. In this context, as a domestic enterprise in scientific research instruments, Ruishi Technology is accelerating the transition of scientific research instruments from "usable" to "easy to use" and from "optional" to "preferred" with its independently controllable core technology, internationally excellent performance, and fully localized services throughout the entire process.

PART.01Build a full chain product matrix and create a domestic scientific research tool

Ruishi Technology takes' independent innovation and domestic substitution 'as its core concept, focuses on the research and development of key instruments in the field of life sciences, and officially launches the full range of Micro CT new products. This series of products surpasses imported similar products in core indicators such as imaging accuracy and scanning speed, marking a significant breakthrough in China's independent research and development capabilities for scientific instruments.

Through continuous technological breakthroughs, Ruishi Technology has successfully built a complete product matrix including three major technology platforms: CT imaging, optical imaging, and precision irradiation (radiotherapy), achieving a leapfrog development from a single device to a system solution.

1、 Heavy release of new Micro CT products across the entire range

1. Small Animal Live Micro CT Imaging System (Model: Imaging 100)

The Imaging 100 Small Animal Live Micro CT Imaging System from Ruishi Technology connects live dynamic monitoring with in vitro fine resolution, breaking through the bottleneck of traditional imaging technology and providing new solutions for biomedical research and transformation.

·In vivo/ex vivo dual-mode compatibility

Breaking the limitations of single imaging, dual modal design solves the problem of data cross validation, and constructs a full cycle research system from physiological function to tissue morphology.

·Intelligent noise reduction imaging

Advanced algorithms improve the signal-to-noise ratio of images by enhancing effective signals and suppressing background noise, resulting in a significant increase in detail resolution and quantitative accuracy of images.

·High speed dynamic capture

Rapid imaging effectively reduces physiological interference caused by prolonged anesthesia in animals, reduces the bias of non experimental factors on results, and significantly improves experimental efficiency and data quality.

2. Ultra high resolution and integrated Micro CT imaging system (model: Imaging 100pro)

Ruishi Technology has developed a new ultra-high resolution and lifelike Micro CT imaging system, IMAGE 100pro, which reshapes a new dimension of scientific research with the intelligence of in vivo and in vitro compatibility, superior signal-to-noise quality, and instant imaging speed.

·High resolution, delicate details are fully displayed

Breaking through traditional limits, achieving a resolution of 1 μ m, accurately presenting the fine structure of biological samples, micro scale branches of vascular networks, and material fiber structures, with clear and visible microscopic details.

·Ultra large field of view, global control

Innovative mechanical structures and algorithms enable high-resolution and precise imaging of samples within a wide field of view, effectively processing massive amounts of data generated by large field imaging and providing powerful tools for multidisciplinary research.

·Fast imaging, efficiency leap

Complete full sample lossless scanning and 3D reconstruction within seconds, using GPU accelerated deep learning algorithms to compress data processing to the second level, balancing high-speed imaging and microscopic accuracy.

3. Micro CT Microscopic Imaging Platform (Model: Imaging 100ultra)

With the mission of "redefining microscopic imaging", Ruishi Technology is committed to creating a new generation Micro CT microscopic imaging platform, the IMAGE 100ultra, which integrates the three core advantages of high resolution, fast imaging, and diverse applications, opening up microscopic insight experiences for scientific research and industrial fields.

·Nanoscale analysis, restoring microscopic truth

Equipped with a micro focus X-ray tube and high-performance detector, using cone beam CT technology, breaking through the resolution limit, accurately presenting dynamic details of biological samples and material microcrack structures.

·Second level imaging, double improvement in efficiency and accuracy

Our self-developed 3D reconstruction algorithm combined with GPU acceleration technology compresses scanning time to the second level, lossless processing of image data, and captures the instantaneous changes in microscopic processes.

·Intelligent interaction simplifies the scientific research process

The ALL-IN-ONE operating platform supports one click imaging and automatic analysis, AI real-time parameter optimization, and provides full chain intelligent support to facilitate efficient innovation in scientific research.

The release of all new products in the Micro CT series further fills the technological gap in this field in China and provides a localized solution to break the industry's long-standing dependence on imported scientific research instruments.

2、 Optical Imaging Product Series

1. Two dimensional optical live imaging system (model: IMAGE 200): Known for high sensitivity imaging, it has extremely low background noise and high signal-to-noise ratio characteristics, and supports multiple fluorescent/bioluminescent probe detections. Its intelligent operation platform can automatically complete ROI recognition and quantitative analysis, and the high-throughput design significantly improves experimental efficiency.

2. The 3D optical live imaging system (model: IMAGE 200pro) has achieved a major breakthrough in domestic technology, with sub millimeter level 3D positioning accuracy and AI organ prediction function, which can accurately track drug distribution paths and analyze tumor 3D morphology. Innovative multi angle image reconstruction algorithms and intelligent analysis systems provide new dimensional data for research on tumor targeted therapy, immune response, and more.

3. 3D Multimodal Precision Imaging System (Model: Imaging 1000): Through the deep fusion of Micro CT and optical imaging, it has innovatively achieved the collaborative visualization of 'structure function'. Its innovative data fusion algorithm supports high-resolution anatomical structure imaging, multi-channel molecular dynamic tracking, and cross scale 3D reconstruction, demonstrating advantages in cutting-edge fields such as tumor treatment evaluation and stem cell tracking. The open design of the system meets the flexible imaging needs from the whole to the local.

The IMAGE series optical live imaging system independently developed by Ruishi Technology has built a research solution from basic to cutting-edge, with three core advantages:

✅ Fully independent technology: 100% localization of key algorithms;

✅ Intelligent operation: integrating AI analysis to improve research efficiency;

✅ Multidimensional data: from two-dimensional to three-dimensional, from single modal to multimodal.

At present, this series of products has been widely used in key fields such as tumor research, drug development, immunotherapy, etc.

IIIPrecision irradiation (radiotherapy) product series

1. X-ray irradiation instrument (model: SHARP 100)

High safety: using lead shielding technology to ensure zero radiation leakage and comply with international safety standards;

Strong stability: equipped with high-performance X-ray tube, supporting wide range dose adjustment, meeting long-term irradiation needs;

Precise local irradiation: Multiple irradiation modules can be selected to achieve targeted irradiation of small animal organs/lesions;

Uniformity: Using graded homogenizer technology, the dose uniformity exceeds that of similar products, ensuring the reproducibility of experiments.

2. X-ray image-guided irradiation instrument (model: SHARP 100pro)

Real time image navigation: integrated high-resolution X-ray imaging, visual positioning correction, to avoid the risk of false illumination;

Intelligent analysis software: Built in irradiation planning system, supporting ROI labeling, dose simulation, and one click export of experimental data;

Efficient scientific research adaptation: compatible with multiple animal models, suitable for research scenarios such as tumor radiotherapy and immunotherapy.

3. CT image-guided irradiation instrument (model: SHARP 200)

3D precision radiotherapy: integrating low-dose Micro CT imaging to achieve 3D reconstruction of tumor target area, supporting IMRT/VMAT radiotherapy technology reproduction;

Intelligent radiotherapy planning: AI assisted delineation of target area, multi angle dynamic irradiation, increasing tumor dose while protecting normal tissue;

Prospective upgrade: Optional Flash therapy module to assist in cutting-edge exploration of radiobiology.

4. Multimodal image-guided irradiation instrument (model: SHARP 1000)

With the mission of "redefining microscopic imaging", Ruishi Technology is committed to creating a new generation Micro CT microscopic imaging platform, the IMAGE 100ultra, which integrates the three core advantages of high resolution, fast imaging, and diverse applications, opening up microscopic insight experiences for scientific research and industrial fields.

Multi modal fusion imaging: The industry integrates Micro CT+3D optical imaging to synchronously obtain anatomical structure and biological function data, solving the problem of blurred target areas in traditional radiotherapy;

Accurate management of the entire process: providing a closed-loop research plan from "target area recognition → image guidance → dynamic irradiation → efficacy evaluation", especially suitable for complex experiments such as PDX models and stem cell therapy;

Grade III radiotherapy system: supports IMRT/VMAT irradiation, with a dose distribution comparable to that of radiotherapy equipment, accelerating translational medicine research.

The SHARP series irradiation instrument independently developed by Ruishi Technology has established a precise radiotherapy research system from basic irradiation to multimodal image guidance, with three core advantages:

✅ Safety: The entire series adopts a high-grade shielded lead design, with radiation protection exceeding the national standard (GB18871-2002), and can be safely used in ordinary laboratories;

✅ Intelligent and precise: integrating image guidance, AI assisted positioning, and graded radiotherapy planning system to achieve scientific research grade precision irradiation;

✅ Flexible Expansion: Supports module upgrades such as Flash therapy and multimodal imaging to meet cutting-edge research needs.

At present, this series of products has been widely used in fields such as tumor radiotherapy research, radiobiology, drug development, and translational medicine.

PART.02From laboratory validation to scientific research collaboration, building a domestic instrument ecosystem

The value of domestic instruments lies not only in their technical parameters, but also in their ability to truly support scientific research and innovation. Ruishi Technology has established in-depth cooperation with more than 50 top institutions, such as Tsinghua University, Peking University and the Chinese Academy of Sciences, to promote the integration of domestic equipment into the whole scientific research chain through joint laboratories, algorithm development, data sharing and other forms.

In September 2024, Ruishi Technology signed a strategic cooperation agreement with the School of Biological and Medical Engineering at Donghua University and established a Micro CT joint laboratory. Both parties deeply integrate their scientific research and technological advantages, focusing on image data analysis, biomedical engineering, and materials science. The aim is to effectively promote the transformation and application of scientific research achievements through the synergistic effect of "1+1>2", accelerate technological innovation and equipment development, and expand the application of new materials in life sciences and fields.

PART.03Endorsed by top international journals, domestic instruments enter the main battlefield of scientific research

Ruishi Technology's equipment is becoming a "standard" for high-level research. In recent years, research achievements based on Ruishi Technology and equipment have been published in multiple top academic journals worldwide, and the instrument performance has been recognized by international peer review.

Professor Sang Hongxun's team at Southern Medical University has made significant breakthroughs in the field of bone regeneration medicine based on the high-precision imaging technology of Ruishi Technology's Micro CT imaging system. Their research results have been published in the top materials science journal Acta Biomaterialia (IF=9.4).

A research team from West China Stomatology of Sichuan University, South China University of Technology, and Columbia University used the Ruishi Technology 2D optical live imaging system for imaging and published the latest results in Advanced Materials (IF=27.6), revealing a new mechanism of nanomaterials regulating macrophage polarization to inhibit refractory muscle fibrosis.

The team led by Professor Zhang Zhen and Professor Wang Yan, affiliated with Fudan University, utilized the Ruishi Technology X-ray irradiator to provide precise irradiation. The study was published in the Journal of Experimental&Clinical Cancer Research (IF: 11.4) to reveal the radiobiological characteristics and treatment response of BRAFV600E mutant colorectal cancer through patient derived organoids.

PART.04Using innovation as an engine to help China's scientific research become independent and self reliant

As of now, Ruishi Technology has successfully obtained SGS international certification and has been awarded three certification certificates: Quality Management System (ISO 9001), Environmental Management System (ISO 14001), and Occupational Health and Safety Management System (ISO 45001). The company has accumulated nearly 100 intellectual property applications and achieved significant technological innovation results. From core component research and development to intelligent software breakthroughs, from single machine equipment manufacturing to providing overall system solutions, Ruishi Technology is continuously enhancing the global market competitiveness of domestic instruments through independent innovation throughout the entire industry chain.

In the future, Ruishi Technology will continue to focus on major national needs, collaborate with universities and research institutes to overcome "bottleneck" technologies, and enable Chinese scientists to explore the world's frontiers with independent instruments, contributing Chinese solutions to global scientific research!