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From 'Weighing' to 'Compliance Management', Sartorius Cubis ® The Technical Breakthrough of the Balance II
Date: 2025-12-17Read: 1

As SartoriusFlagship series of laboratory scales, Cubis ® II takes "full scenario customization, strong environmental adaptation, and strict compliance management" as its core,

With innovative technologies such as modular design and fourth generation supercell sensors, we cover the needs of ultra micro, micro, semi micro, and large range weighing,
Becoming the core analytical equipment for regulated industries such as pharmaceuticals, biology, and chemistry, it not only meets the requirements of daily precision weighing, but also adapts to the data reliability requirements in strict regulatory environments.
The following analysis will be conducted from four aspects: core technology, featured functions, application scenarios, and maintenance standards.


1、 Core technical parameters: comprehensive coverage of accuracy and range


Cubis ® The II series offers 45 weighing modules and multi range combinations, suitable for different laboratory scenarios:

• Range and accuracy: The large range microbalance can weigh up to 111g, with readability as low as 1 μ g; Semi micro balance with a range of 120-220g
The readability accuracy is 5-10 μ g, maintaining extremely low measurement uncertainty over the full range, and the minimum sample weight meets the requirements of pharmacopoeias such as USP.

Core Sensor: Equipped with the fourth generation super unit sensor, combined with an intelligent environment compensation system, it automatically offsets the effects of temperature, humidity, and air pressure changes, with the shortest stabilization time for similar products, ensuring measurement repeatability in complex environments.

• Structural design: Titanium non-magnetic weighing plate and sample holder, expanding the weighing area by 66%, equipped with a detachable anti overflow weighing plate (capable of withstanding 50mL of chemicals), balancing weighing convenience and anti pollution ability.


2、 Core Features: Modularization, Compliance, and Intelligence in One


1. Thousand level customized modular platform

Supports 4-step quick configuration of hardware and software, with 2 user interfaces, 7 types of wind shields and ionizers, electric wind shields and other hardware options available. After purchase, the functionality can be flexibly upgraded without the need to replace the entire machine, reducing initial investment costs.


2. Compliant intelligent management system

Software adaptation: Equipped with specialized software packages such as Pharma QApp Package, supporting user management, electronic signatures, audit tracking, and other functions,
Compliant with 21 CFR Part 11, EU Annex 11, and GxP requirements, the cleaning QApp can guide daily/deep cleaning processes and record them, integrated into SOP management.

Data interconnection: Supports direct connection to ELN/LIMS systems or indirect integration through Ingenix Suite software, avoiding manual transcription errors and achieving centralized data storage and full traceability.


3. Environmental adaptation and ergonomic optimization

Anti interference design: Windproof cover with special conductive coating, built-in four nozzle electrostatic precipitator, can eliminate sample static electricity and avoid weight drift; The electric leveling function achieves automatic calibration and improves operational efficiency.

Humanized operation: tool free disassembly of components, contactless operation design, reducing cross contamination; Provide specialized sample holders such as flasks and reaction tubes to meet diverse weighing needs and comply with ergonomic design.


3、 Typical application scenarios: covering the precision weighing needs of multiple industries


• Pharmaceutical and Biopharmaceutical: Meet the needs of raw material weighing, standard preparation, cell passaging, etc., comply with USP and European Pharmacopoeia 2.1.7 requirements, and adapt to sterile operations and compliance audit scenarios.

• Chemical and Environmental Analysis: Suitable for quantitative weight analysis, elemental analysis and other trace sample weighing, anti overflow design and chemical corrosion resistance characteristics, suitable for laboratory routine analysis and pollution sample detection.

Academic research and manufacturing: supporting scenarios such as new material research and development, precision weighing of electronic components, modular configuration that can match the dynamic needs of different research directions, high resolution and environmental adaptability for laboratory and pilot plant use.


4、 Key maintenance standards: ensuring long-term stability of accuracy and compliance


• Daily cleaning: Use a specialized cleaning kit (hard brush, soft brush, dry cloth, etc.), follow QApp instructions, wipe the components with compatible cleaning agents after disassembly, dry them before reassembly, and avoid liquids entering the equipment opening.

• Regular calibration: Conduct deep cleaning and calibration every quarter, use standard weights to verify accuracy, and ensure compliance with regulatory requirements; The built-in electrostatic discharge nozzle should be avoided from touching to prevent damage.

• Storage and handling: Keep a dry environment when idle and avoid severe vibrations; After long-term disuse, it is necessary to calibrate the sensor before use to ensure stable performance.