Multi laser nanoparticle analyzerThe flexibility is reflected in multiple dimensions such as technical design, adaptability to application scenarios, and operational modes, which can meet diverse needs from basic research to industrial production.
Multi laser nanoparticle analyzerdetailed description:
1、 Technical flexibility: multi laser collaboration and adjustable parameters
Dynamic combination of laser wavelength and power
Wavelength selection: By integrating lasers of different wavelengths (such as 405 nm, 532 nm, 633 nm), scattering signals can be optimized for particles of different sizes and materials. For example:
Small particles (<100 nm): Short wavelength lasers (such as 405 nm) provide higher sensitivity and reduce Brownian motion noise interference.
Large particles (>1 μ m): Long wavelength lasers (such as 633 nm) reduce multiple scattering effects and enhance signal intensity.
Power adjustment: Users can dynamically adjust the laser power according to the sample concentration to avoid signal saturation of high concentration samples or weak signal of low concentration samples. For example, HORIBA ViewSizer 3000 supports continuous adjustable power within the range of 10 mW to 300 mW.
Multi mode switching of detection angles
Forward scattering (12.8 °): enhances detection sensitivity for large particles (>500 nm), suitable for micro particle analysis.
Backscatter (175 °): Suppresses multiple scattering effects and is suitable for measuring nanoscale particles in high concentration samples such as protein solutions and colloids.
Lateral scattering (90 °): Provides particle morphology information (such as spherical and rod-shaped) to assist in distinguishing different morphologies of nanomaterials.
Intelligent adaptation of temperature and viscosity compensation
Built in Peltier temperature control module (accuracy ± 0.1 ° C), which can simulate the internal environment of living organisms (such as 37 ° C) or industrial reaction conditions (such as 80 ° C), ensuring the authenticity of measurement results.
Support custom solvent viscosity parameters, compatible with multiple sample systems such as water, organic solvents, polymer solutions, etc.
2、 Flexibility at the functional level: full process coverage and multi parameter output
Wide compatibility of sample types
Volume adaptation: It can be measured from trace samples (350 μ L) to conventional volumes (1.25 mL), reducing the consumption of precious samples such as cerebrospinal fluid and extracellular vesicles.
Concentration range: Supports a wide concentration range of 5 × 10 ⁶ -2 × 10 ⁸ particles/mL, allowing for direct analysis of high concentration suspensions (such as nano gold sols and ceramic slurries) without dilution.
State compatibility: it can measure transparent liquid, emulsion, colloid and even semi-solid samples (such as gel), and prevent particle sedimentation through vibration module.
Multi parameter synchronous analysis
Particle size distribution: Output statistical parameters such as D10, D50, D90, and plot volume distribution, quantity distribution, or intensity distribution curves.
Particle concentration: Combined with NTA technology, directly calculate the number of particles per unit volume (particles/mL) without the need for additional calibration.
Zeta potential (optional): Integrated electrophoretic light scattering module, analyzing particle surface charge and stability, guiding the optimization of nanoparticle dispersion process.
Real time monitoring of dynamic processes
Time resolved measurement: Continuously recording particle size changes at second intervals to capture dynamic processes such as aggregation, crystallization, and degradation. For example:
Monitor the aggregation behavior of proteins under heating conditions to prevent the risk of precipitation in drug formulations.
Track the size evolution of nanoparticles under shear force, and optimize the stability of lotion.
3、 Flexibility at the operational level: user-friendly and scenario based customization
Intelligent design of software interface
One click measurement: preset commonly used protocols (such as exosomes, liposomes, nanomedicines), novice users can quickly get started.
Multi language support: Provides interfaces in over 10 languages including Chinese, English, Japanese, and German to meet the needs of global laboratories.
Data export compatibility: Supports CSV, Excel, PDF and other formats, and can be directly imported into Origin, MATLAB and other software for in-depth analysis.
Modular hardware expansion
Optional accessories: Install Zeta potential detection module, fluorescence detection module, or high-temperature temperature control module according to requirements to achieve functional upgrades.
Sample Cell Replacement: Provides multiple options such as disposable colorimetric dishes, reusable quartz cells, and flow cells to meet different cleanliness and cost requirements.
Cross platform data integration
API interface openness: Supports integration with LIMS (Laboratory Information Management System) and PLC (Industrial Control System) to achieve automated data collection and production process linkage.
Remote control: remotely starting measurement and monitoring progress through LAN or cloud platform, suitable for unmanned laboratory or hazardous environment operations.
4、 Flexibility of application scenarios: seamless connection from laboratory to production line
academic research
Multidisciplinary intersection: The same instrument can serve multiple fields such as materials science (nanoparticle synthesis), biology (extracellular vesicle research), chemistry (colloid chemistry), etc.
Method development: Users can customize parameters such as laser power and detection angle to explore characterization methods for new nanomaterials.
Industrial Quality Control
Online detection: By connecting the flow pool module to the production line, the size distribution of nanoparticles is monitored in real-time to prevent batch differences.
Anti fault diagnosis: Based on the trend of particle size changes, quickly locate abnormalities in the production process (such as insufficient grinding, uncontrolled polymerization reaction).
Environmental Monitoring and Public Health
On site rapid detection: Portable multi laser analyzer can be deployed in the field to analyze nanoplastics in water or PM0.1 particles in the atmosphere.
Emergency response: During the epidemic, quickly detect the particle size distribution of virus aerosols and assess the risk of transmission.