The biochemical analyzer used in the laboratory has a large daily water volume and is mainly used for key processes such as calibration, blank testing, reaction cup cleaning, dilution of concentrated reagents, and flushing of instrument pipelines. Impurities in water can cause a higher blank absorbance value, which in turn affects the accuracy, stability, and repeatability of the test results. Stable and reliable pure water is the key to ensuring the reliability of every inspection report.

　　The influence of impurities in water on biochemical detection

　　1)ion

Ions in water can interfere with the measurement results of Mg ²+and Ca ² ⁺ ions.

The indicators detected by oxidase method are affected because many ions can affect the activity of enzymes, thereby affecting the measurement results.

　　2)microorganism

Microorganisms adhering to the pipelines and reaction systems of biochemical analyzers may cause blockages in the pipelines and increase the blank value of the reaction cup.

The metabolic products of microorganisms also have an impact on biochemical indicators such as total bile acids.

　　3)organic matter

Organic compounds can cause false overestimation in the determination of specific similar substances.

Organic matter adheres to the inner wall of the pipeline and the surface of the reaction cup, exacerbating the difficulty of cleaning and affecting the service life and detection accuracy.

　　4)particle

Particles entering the pipeline or reaction system of a biochemical analyzer can not only cause an abnormal increase in absorbance, but may also lead to pipeline blockage or even damage to the reaction cup, seriously affecting the accuracy of the detection results.

The water standards for biochemical analyzers can refer to GB/T 6682-2008 "Specifications and Test Methods for Analytical Laboratory Water", WST574-2018 "Purified Water for Clinical Laboratory Reagents", and the regulations of the Clinical Laboratory Standards Institute (CLSI) in the United States. Different models of biochemical analyzers have different requirements for water quality. Currently, most biochemical analyzers refer to the clinical laboratory reagent pure water CLRW for their water quality requirements. The specific indicators are shown in the table below:

Table 1 Water indicators for biochemical analyzer

The pure water system equipped with the laboratory biochemical analyzer not only requires water quality to meet standards, but also has higher performance requirements for the product. The following conditions must be met:

1) High water demand: During peak hours, water usage is concentrated, and pure water systems need to have high production capacity.

2) Water quality stability: It is necessary to continuously and stably provide high-quality pure water to avoid fluctuations in water quality affecting the test results.

3) Space limitation: The system design should be compact and reduce the footprint.

4) Easy maintenance: user-friendly interface and convenient replacement of consumables.

5) Effective bacterial control: It is necessary to effectively inhibit microbial reproduction and prevent biofilm formation.

To address these challenges, a professional and reliable pure water system has become an important equipment in the laboratory. RephiLe, with its deep accumulation in the field of pure water, has launched a desktop high flow Genie C intelligent pure water system designed specifically for large clinical laboratory testing.

The high flow Genie C integrates powerful performance into a compact space, exquisite and low noise, ensuring high flow while reducing space occupation. It integrates mature water purification technology and modern IoT management and monitoring technology to ensure high-quality water production and reliable and stable system use.

　　High traffic Genie C core technology

1) Using Lefeng's specially designed small volume high-throughput RO membrane, the RO water production flow rate is constant and not affected by environmental temperature

2) LeFil and OrganeFil formula packed purification columns effectively remove ions and organic impurities

3) Adopting UVC LED mercury free ultraviolet lamp for efficient sterilization

4) Real time monitoring of the entire pipeline, allowing for real-time monitoring of the operation status of each link in the pure water system through the main control screen, and timely elimination of potential risks