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Core structure and design features of research grade inverted biological microscope
Date: 2025-11-28Read: 0
Research grade inverted biological microscopeIt is a high-precision optical instrument designed specifically for long-term live cell research and complex sample analysis.

Research grade inverted biological microscopeCore structure and design features:

Inverted optical system:

The objective lens is located below the stage, and the illumination system is located above the stage. This design can accommodate thick walled containers such as culture bottles, culture dishes, and porous plates, allowing for direct observation of live cells without the need for slicing, avoiding sample damage.

The stage is mostly a large-sized electric platform that supports high-precision movement along the XY axis. Some models are equipped with Z-axis focusing drive to achieve automatic focusing and multi-layer imaging.

objective system

Equipped with high-performance objectives such as flat field achromatic lens and flat field apochromatic lens, with higher numerical aperture (NA) and resolution, it can clearly distinguish organelles inside cells.

Equipped with a long working distance objective lens, suitable for observing thick samples or covered culture containers, and the objective lens is corrosion-resistant, resistant to culture solution contamination, and easy to clean.

Lighting and imaging system

Transmitting lighting: using Kohler lighting, combined with halogen lamps and LED cold light sources, the light is uniform and the brightness can be adjusted to reduce sample thermal damage, suitable for bright field, phase difference, and differential interference (DIC) observation.

Fluorescent lighting: equipped with mercury lamps, LED fluorescent light sources or laser light sources, paired with filter groups, supporting multi-color fluorescent labeling imaging.

Imaging component: equipped with high-resolution research grade CCD/CMOS cameras, supporting high-speed imaging and low light capture, capable of recording the dynamic processes of living cells; Some models are compatible with confocal scanning modules to achieve 3D fluorescence imaging.

Regulation and Control System

Equipped with an electric focusing system, it has high focusing accuracy and can stably maintain the focal plane, meeting the needs of long-term live observation.

Adopting a computer intelligent control system, parameters such as light source intensity, objective lens switching, and filter group selection can be adjusted through software, while supporting image acquisition, analysis, storage, and sharing.