Applicable materials of vacuum spray dryer

The vacuum spray dryer is especially suitable for materials with heat sensitivity, easy oxidation, organic solvent or high added value. It can dry rapidly at low temperature and effectively protect the activity and quality of materials.
The vacuum spray dryer (especially the low temperature type) can significantly reduce the boiling point of water (drying can be completed at 30 ℃ – 80 ℃) by carrying out spray drying in a vacuum environment to avoid the damage of high temperature to materials. Meanwhile, the low oxygen environment reduces the risk of oxidation, making it an ideal choice for handling sensitive materials. This technology is widely used in fields such as food, medicine, chemical and biological products.
Applicable material types
The following are the main applicable categories based on material characteristics:
Specific examples of material categories, key advantages, and sources
(1) Thermally sensitive biological products include enzyme preparations, vitamins, proteins, live bacteria, and vaccines that prevent denaturation and inactivation at low temperatures, while retaining their biological activity
(2) Sugar/natural extract Chinese medicine extract, fruit juice powder, plant polyphenols, anthocyanins to avoid coking and Maillard reaction, maintain color and flavor
(3) Easily oxidized or volatile substances unsaturated fatty acids (such as DHA), essence and fragrances, and some pharmaceutical ingredients reduce oxygen exposure in vacuum, and control the rate of volatilization
(4) Ethanol extract, acetone solution, and polymer solution containing organic solvents can be equipped with a closed-loop circulation system to recover solvents, ensuring safety and environmental protection
(5) Polymer and functional material drug sustained-release microspheres, nanocarriers, and battery material precursors control particle morphology to obtain powders with good sphericity and uniform particle size
In addition, for materials with high viscosity or high humidity, low-temperature vacuum conditions can effectively prevent nozzle clogging and improve drying efficiency. The equipment is usually equipped with automatic needle cleaning function to further ensure continuous operation.