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Microbial invasion method sealing tester? What can be done specifically?
Date: 2025-11-19Read: 40

How much do you know about the microbial invasion method sealing tester? What specific actions can be taken? Today, let's take a closer look at this device!


Image of detection instrument: LT-PNP microbial invasion tester

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Principle:


Evaluate the sealing performance of packaging by simulating the penetration of microorganisms in a sealed environment. It utilizes the small volume and activity of microorganisms to accurately detect tiny loopholes in packaging.

Application:

Whether it is food, medicine or daily chemical products, as long as it involves sealed packaging, it can be used. Ensure that the products are fresh and safe, giving consumers more peace of mind.

use:

Microbial invasion sealing test, also known as microbial challenge method sealing integrity test, is usually conducted simultaneously with simulated filling. By simulating the filling of the culture medium according to the simulation filling verification plan, followed by plugging and capping, the visual inspection is qualified. After sterilization in the validated sterilization cabinet, the sealing surface of the container is immersed in a high concentration of bacterial solution, so that the culture medium in the sample container fully contacts the inner surface of the seal. The neck of the sample and the outer surface of the seal should be immersed in the bacterial suspension. After soaking for a certain period of time, it is taken out and regularly cultured to check for microbial invasion, in order to determine the integrity of the container sealing system. At the same time, a positive control test needs to be conducted to confirm the growth promoting ability of the culture medium. Vacuum or overpressure challenge conditions are usually used in testing, and sealed testers (microbial invasion testers) can meet the relevant requirements for negative pressure vacuum and positive pressure overpressure test conditions.

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