Cellular bioreactorWidely used in fields such as medicine, agriculture, and environmental protection. Here is the detailed information:
Type:
Stirring bioreactor: suspends and aerates cells through mechanical stirring, suitable for large-scale cultivation.
Non stirred bioreactors: including air lift, bubble, and drum types, suitable for cell culture sensitive to shear forces.
Fixed cultivation bioreactor: Fixing cells on a carrier to reduce shear force, suitable for continuous cultivation or biotransformation.
Photobioreactor: Increasing the illumination system to meet the photosynthesis needs of plants.
Disposable bioreactor: using biocompatible plastics, suitable for laboratory scale production.
Maintenance of temperature control system:
Regular inspection: calibrate temperature sensors, check the sealing of heating/cooling units, circulation pumps, and pipelines to ensure temperature control accuracy (± 0.1 ℃).
Medium cleaning: Water or thermal oil systems need to have their medium replaced regularly to prevent scaling or microbial contamination.
Safety testing: Verify the functions of overheat protection, overpressure alarm and other devices, record operating data to predict faults.
Aseptic and cleaning process:
In situ sterilization: Use an independent sterilization system (such as 121 ℃ steam) to treat the reactor walls, pipelines, and valves to avoid cross contamination.
Flow chamber cleaning: Rinse the pipeline with PBS or 0.1% sodium hypochlorite after testing, and clean the nozzle with ultrasound (10-15 minutes).
Optical components: Wipe the laser lens with anhydrous ethanol and dust-free cloth to prevent dust from affecting the detection accuracy.