The threaded transparent brown glass sample bottle has a wide range of applications in the laboratory, and its design standards and material characteristics serve the stable storage and safe transportation of samples. The following are specific applications and standard analysis:
1、 Core purpose
Chemical sample storage and transportation
Suitable for storing volatile, corrosive, or photosensitive chemical reagents, such as organic solvents (acetonitrile, methanol), strong acids and bases, and biological samples (such as amino acids, proteins).
The brown bottle body can filter ultraviolet rays to prevent photolysis reactions, while the transparent version facilitates observation of sample status (such as precipitation and layering).
Chromatographic analysis injection container
Widely used in analytical techniques such as gas chromatography (GC) and liquid chromatography (LC), it needs to be used in conjunction with an automatic sampler.
The thread design ensures sealing, prevents sample evaporation or contamination, and guarantees the accuracy of analysis results.
Long term storage and stability research
Glass materials (such as first grade hydrolyzed glass and low borosilicate glass) have chemical inertness, can withstand high temperature and high pressure sterilization, and are suitable for long-term storage of samples.
Equipped with silicone or PTFE gaskets to further enhance sealing and reduce the risk of sample evaporation or cross contamination.
2、 Design standards and specifications
Bottle mouth thread size
Following international standards (such as GL series), common specifications include:
GL-12: with an outer diameter of approximately 12mm, suitable for small capacity bottles of 1mL, 2mL, and 5mL.
GL-25: outer diameter of approximately 25mm, suitable for 10mL and 20mL bottles.
GL-32/GL-45: Suitable for large capacity bottles of 50mL, 100mL, and above respectively.
The thread pitch is usually 1.0mm, 1.5mm, or 2.0mm to ensure a tight fit with the bottle cap.
Material and chemical compatibility
Glass material:
First grade hydrolyzed glass or low borosilicate glass, resistant to high temperatures and corrosion, suitable for organic solvents and strong acids and alkalis.
Compliant with the requirements of the United States and European Pharmacopoeias, it can be used for drug development and production.
Plastic material (PP/PE):
Lightweight and drop resistant, but it needs to be confirmed whether it can withstand experimental solvents (such as alkaline substances that may corrode the PP bottle body).
Sealing and Accessories
Bottle cap material: polypropylene (PP) or polyethylene (PE), with strong chemical inertness to avoid contaminating the sample.
Gasket material:
Silicone pad: economical and suitable, but has weak chemical resistance.
PTFE pad: resistant to high temperature and corrosion, suitable for strong solvents or high-temperature sterilization.
PTFE/silicone composite pad: Combining the advantages of both, suitable for headspace sampling or long-term storage.
Size and Capacity
Common capacities: 2mL, 4mL, 10mL, 20mL, 50mL, etc., to meet different analysis needs.
The diameter and height of the bottle body need to match the gripping specifications of the automatic sampler to ensure smooth operation.
3、 Application scenario examples
environmental monitoring
Store water samples, soil extracts, etc. The brown bottle body prevents photolysis to ensure sample stability.
pharmaceutical industry
Used for quality control of pharmaceutical intermediates or finished products, in compliance with GMP standards, to avoid cross contamination.
food testing
Store samples of food additives or pesticide residues in transparent bottles for easy observation of color changes.
academic research
University laboratories are used to store standard or reference materials, and low borosilicate glass materials should be selected for long-term storage.
4、 Selection suggestions
Select bottle body color based on sample properties:
Brown bottles are preferred for photosensitive samples such as vitamins and antibiotics.
Select transparent bottles for samples that require observation of their state, such as crystallization and precipitation.
Select bottle mouth specifications based on analysis methods:
The automatic sampler needs to be matched with GL-12 or GL-25 threads to ensure gripping accuracy.
Manual injection can use a clamp bottle, which has better sealing but requires specialized tools to open.
Select materials based on storage conditions:
Low borosilicate glass is preferred for long-term high-temperature sterilization or storage of strong solvents.
When there is a need for lightweight storage or transportation in the short term, PP material can be selected.