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What are the common applications of multifunctional atomic force microscopy?
Date: 2025-07-13Read: 1
Multi functional atomic force microscope is a high-precision scanning detection tool widely used in various fields such as physics, chemistry, biology, materials science, etc. Mainly by scanning the surface of an object and utilizing atomic level force to obtain three-dimensional morphology information of the object surface.

The basic principle of atomic force microscopy:
1. Probe sample interaction: The core of atomic force microscopy is the interaction force between the probe and the sample surface. Probes are usually made of hard materials such as silicon, silicon nitride, etc., with very sharp tips and dimensions of several nanometers. The different structures or physical properties of the sample surface can affect the movement of the probe, resulting in different force signals.
2. Types of Forces: There are several types of forces detected by atomic force microscopy, including van der Waals forces, electrostatic forces, chemical bond forces, and repulsive forces between atoms. By measuring the changes in these forces, the microscope can accurately depict the microstructure of the sample surface.
3. Scanning mode: AFM scanning modes usually include contact mode, non-contact mode, and jump mode. In contact mode, the probe is in direct contact with the sample surface; In non-contact mode, the probe maintains a certain distance from the sample surface and obtains information by sensing the interaction force between the two; The jumping mode is when the probe periodically moves away from and approaches the surface of the sample during the scanning process to avoid direct contact and damage to the sample.
  Multi functional atomic force microscopeApplication areas:
1. Materials Science: AFM is widely used in materials science for surface morphology research, mechanical property testing, and micro/nano structure research. It can help researchers understand the microstructure of materials, their mechanical properties, and the differences between different materials.
2. Biology and Medicine: In the field of biology, AFM is used to observe biological samples such as cell surfaces, protein structures, DNA molecules, etc. Its high-resolution imaging capability makes it an ideal tool for studying the interactions between cell membranes and molecules. Meanwhile, AFM can also be used to measure the mechanical properties of cells, such as stiffness and flexibility, helping scientists understand the biomechanical behavior of cells.
3. Nanotechnology: AFM is widely used in nanotechnology research, especially in the preparation and analysis of nanomaterials and nanodevices. It can accurately locate and analyze nanoscale structures, providing important experimental data for the design and optimization of nanodevices.
4. Semiconductor industry: AFM is used in the semiconductor industry to inspect the surface structure of chips, measure small defects and surface roughness, etc. It can effectively improve the accuracy and quality control level of chip manufacturing.
5. Environmental Science: AFM can also be used for the detection and analysis of environmental pollutants, such as studying the surface characteristics and size distribution of heavy metals and microplastics.