New product launch|Zeiss Wide Field Imaging 'New' Realm

In the exploration of life sciences, fluorescence microscopy plays an important role. By capturing the fluorescence signal of samples, we can see images with rich details. But with the continuous development of technology, scientists have more expectations for wide field images:

Ø How to remove defocused signals from wide fields and obtain reliable laboratory data

Ø How to choose a suitable light source for better excitation of fluorescence signals

Ø How to improve the wide field imaging experience and enhance work efficiency

Zeiss wide field fast high-resolution imaging solution takes you into a new realm of wide field imaging. Utilize powerfulApotome PlusandViluma familyThe light source helps you further improve the image quality of wide fields.

u New feature: Brand newAptome PlusHelp you effectively remove defocused signals

u New component: brand newViluma familyMeet various application requirements

u New experience: Intelligent workflow helps you handle different samples with ease

New features:

u More precise viewing:High precision restoration of the three-dimensional structure of the sample

▲4Juvenile zebrafish of different ages, labeled with glial fibrillary acidic protein, acetylated microtubule protein, andDNAThe sample was collected by the Leibniz Institute for Aging Research in Germany-Fritz·Lipman Institute（FLIofH. ReuterProvide.

u More authentic looking: trustworthy data

▲ UseHoechst 33342Stained giant liver leech. The uniform fluorescence inside the wide field image (left) poses a serious problem for the background correction algorithm (center). Although some structures still exist, overall there are too many black spaces between cells. Compare the results with ZeissApotomeWhen comparing the optical slices obtained (on the right), these areas become visible again. It is worth noting that the prominent edges around the structure seen in the background corrected image in the middle, namely the interference artifacts in the wide field image, areApotomeNot visible in the image.

u Clearer View: Subcellular Wide Field Imaging

▲ Adult mouse brain35MmCoronary section. Using withApotomeofZEISS Axio ObserverImaging with a microscope, utilizingApotome PlusPerform image processing. Sample from University of California, Davis/NIH NeuroMabImaging platform provided.

New components：

Your experiments typically require specific fluorescent labeling excited at appropriate wavelengths, stable and efficient illumination for obtaining reproducible data, and ultra fast live cell imaging. ZeissVilumThe light source is designed specifically for Zeiss microscopes to improve transmittance and minimize crosstalkZENSeamless software integration to meet your various application needs.

▲Viluma family（Viluma 5/7/9）

l high power

l Meet the requirements of multi-color imaging without cross color interference

l Long term stability

New Experience:

Based on the specific application scenario of your experiment, Zeiss can provide you with a comprehensive solution from digital light cutting to hardware light cutting, and then to high-resolution light cutting: to help you
1Wide sample compatibility to meet your diverse application needs
2No need for excessive parameter adjustment, simple and easy to use
3Synchronous collection, synchronous processing, one click completion

▲Comparison between Zeiss digital light cutting scheme (right image) and wide field imaging (left image)

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