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E-mail
aoxuelg@vip.163.com
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Phone
13601697841
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Address
Room 1606, Modern Transportation Building, 218 Hengfeng Road, Zhabei District, Shanghai
British Applied Optics Shanghai Representative Office
Company Profile
- Company Name:
- British Applied Optics Shanghai Representative Office
- Year Established:
- 2026/3/5 9:34:12
- Registered Capital:
- Main Products:
- Address:
- Room 1606, Modern Transportation Building, 218 Hengfeng Road, Zhabei District, Shanghai
Applied Photophysics Ltd. (APL)
Applied Photophysics Ltd, UK（British Applied Optics Shanghai Representative OfficeWe are a professional scientific instrument R&D and manufacturing company. Our products include circular dichroism CD spectrometer, stopped flow reaction kinetics analyzer, laser flash photolysis analyzer (transient absorption spectrometer), etc., which are widely used in the research of molecular spatial structure and conformation, intermolecular interactions, and fast reaction kinetics analysis, especially in the study of structures and interactions between biomolecules, biomolecules and organic small molecules such as drugs, various chiral compounds, etc.
Chirascan series circular dichroism CD spectrometerA new standard has been established for static circular dichroism spectroscopy analysis, adopting various new technologies and designs to achieve high light intensity, especially in the far ultraviolet region. Its advanced and precise digital data acquisition system can achieve fast and accurate spectral acquisition.
Including and configurable multiple functional modules (absorption, fluorescence, full fluorescence spectroscopy, line dichroism (LD), fluorescence detection circular dichroism (FDCD), synchronous 3D fluorescence CCD detection, fluorescence polarization anisotropy spectrum FP (Fluorescence Polarization), fluorescence circular dichroism CPL (circularly polarized luminescence), magnetic CD (MCD), ORD (optical dispersion), low-temperature detection accessories, titration system, transmission method detection of solid powder samples, diffuse reflectance method integrating sphere detection device, stopped flow system, etc.), CPL circularly polarized luminescence and other detection accessories, in order to obtain high standard, high-quality, reliable and verifiable results for various research purposes. Data. There are a large number of high-level scientific research papers and basic research results data from this series of instruments.
It is a commonly used basic research tool in drug development, drug screening and other basic application research. Familiar pharmaceutical companies in the industry such as Amgen, GSK, AstraZeneca, Novo Nordisk, Eli Lilly, Roche, Genzyme, BMS, Riverside, etc. have multiple instruments of this series playing an important role in various research groups.
The circular dichroism CD (Chirascan series) produced by Applied Photophysics in the UK Spectrometers are available at Tsinghua University (currently 6 sets), Peking University (currently 2 sets), Wuhan University (currently 2 sets), Sichuan University (currently 3 sets), Sun Yat sen University (currently 3 sets), South China University of Technology (currently 3 sets), Shandong University (currently 2 sets), Fudan University (2 sets), Shanghai University of Science and Technology (2 sets), Institute of Biophysics, Institute of Chemistry, Institute of Microbiology, Chinese Academy of Sciences (currently 3 sets), Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai Institute of Biochemistry, Chinese Academy of Sciences, Shanghai Pasteur Institute, Chinese Academy of Sciences, Wuhan Institute of Virology, Chinese Academy of Sciences Guangzhou Institute of Biomedical and Health Sciences, Chinese Academy of Sciences The laboratories of China Food and Drug Inspection and Research Institute, Shanghai WuXi AppTec, Shanghai Zhongke New Life Biotechnology Co., Ltd., Shanghai Hengrui Pharmaceutical, Shanghai Fuhong Hanlin Pharmaceutical, Shanghai Sansheng Guojian Pharmaceutical, Beijing Shenzhou Cell Biotechnology Co., Ltd., Shenzhen Hanyu Pharmaceutical, Shandong New Era Pharmaceutical, etc. have good applications and have good literature citations and publications of influencing factors.
CD round two-colorspectrometer Chirascan,Chirascan-plus ， chirascan VX ， chirascan V 100 ， ， chirascan Q 100Circular Dichroism Spectrometers
Chirascan and Chirascan-plus， Chirascan V100 are the world's most advanced circular dichroism (CD) spectrometers. They are widely used in the study of the higher structures of bio-macromolecules, such as proteins and DNA, and how these structures change on interaction with other molecular entities. Their many innovative features provide the scientist with easy-to-use, productive tools that deliver circular dichroism spectra of a quality and on a timescale that has until recently been impossible.
Stop flow（stopped flow）Technology is used to study the kinetic mechanisms of very rapid reactions in solution systems, with reaction times typically ranging from 0.001 seconds to seconds. By studying instantaneous reaction kinetics phenomena, basic information such as reaction rate, mechanism, and intermediate transition states that have existed for a short period of time can be reflected.
The SX20 series of stop flow spectrometers produced by Applied Photophysics Ltd in the UK, as well as previous series such as SX 18 MV, SX 17, SX 15, SX 12, etc., have a data citation rate of over 80% of the searchable published literature.
The optional functional modules include time-resolved absorption analysis, secondary tube array detector PDA, dual fluorescence detection, fluorescence polarization FP (Fluorescence Polarization) detection, multi-channel sequence mixing system, quenching flow detection, electrochemical detection, and CD circular dichroism flow analysis system.
The SX20 is the latest in the SX range of stopped-flow reaction analysers from Applied Photophysics and is used to study transient and pre-steady-state kinetics of fast, liquid-phase reactions. The SX range has, since its introduction over 15 years ago, established itself as the first choice of those involved in stopped-flow kinetic research. The SX20 and its predecessors offer unrivalled performance, as well as a host of upgrade opportunities for the detailed investigation of chemical and biochemical reaction mechanisms.
RX.2000The rapid mixing stop flow device can be used in conjunction with various models of UV visible spectrophotometers (such as Agilent 8453, 8454, Varian Cary 50100, 3003000, etc.), fluorescence spectrometers (such as Hitachi Fluorescence F-4000, F-4500, F-4600, F-7000, Varian series fluorescence spectrometers, PE fluorescence spectrometers, etc.), CD spectrometers, to study rapid kinetic reactions in milliseconds. Compact, convenient, and cost-effective.
RX.2000 Rapid Mixing Stopped-Flow Unit
The RX.2000 provides the means to measure stopped-flow rapid reaction kinetics using any UV-visible spectrometer, fluorometer or CD spectropolarimeter. This high performance, cost effective unit enables reactions to be studied that are at least a thousand fold faster than those accessible manually.
In the thriving biopharmaceutical industry:
Applied Photophysics Ltd, a British applied photophysics companyAs a professional manufacturer of circular dichroism CD spectrometers and stop flow spectrometers, Chirascan series circular dichroism CD spectrometers are used for analyzing biomolecules such as proteins DNA 、 The classic method for advanced structures (secondary structure, tertiary structure) of peptides and other substances is widely used in the field of biopharmaceuticals at home and abroad. The Chirascan series circular dichroism spectrometer has revolutionized the accuracy and precision of circular dichroism detection compared to traditional circular dichroism instruments, greatly expanding the application of circular dichroism spectroscopy CD, especially in the characterization of advanced structures and comparative studies of advanced structural similarities in the biopharmaceutical industry. It is equipped with data statistical analysis methods and software that comply with FDA industry guidelines for data processing and analysis by industry professionals. A large number of users in the same industry facilitate data comparison, verification, evaluation, and mutual recognition.
Keeping up with the development of the biopharmaceutical industry, Applied Photophysics, a British company, has launched the protein chemical stability analysis solution SUPR-CM, which is used to screen suitable protein concentrations for faster screening of formulations or drug candidates. Its fast (384 well plate, scanning one plate in 2.5 minutes), automated, high-throughput, high-sensitivity and high-quality data (CCD fluorescence detection), and the ability to set any incubation time such as 24 hours, 48 hours, or even longer (unlike the current market limitation of 2 hours, etc.) technology design has been well received by industry insiders.
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