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The Sea God Needle developed by the method is the stable choice for the Double 11 ZORBAX StableBond series
Date: 2025-11-05Read: 0
The ZORBAX StableBond (SB) series chromatography column, launched in 1990, pioneered the use ofLarge volume side chain protectionofUnfolded end bonding technologyThis innovative design based on silicone matrix has successfully solved the problemLow pHThe hydrolysis of silicon oxygen bonds in the environment leads to C18/C8Bond phase lossThe industry challenges have established its classic position among numerous analytical methods.
Multiple bonding phases and specifications
Years of user endorsement, considered a classic
Special bonding phase design, able to maintain stability under low pH conditions, effectively preventing the loss of bonding phases
The core advantage lies in the large volume side chain space resistance and unsealed end design
In addition to hydrophobic interactions, it can also provide various forces such as hydrogen bonds, ions, and steric hindrance
Providing selectivity that differs from conventional capped chromatography columns is a powerful tool for method development
6 types of bonding phases: providing different selectivity to meet diverse separation needs
Multiple particle sizes: including 1.8 μ m, 3.5 μ m, 5 μ m, etc., suitable for different application scenarios from rapid analysis to conventional separation
(Click to view large image)
Excellent stability
ZORBAX SB-C18 is far superior in stability compared to various brands on the market under low pH (pH 0.8) and high temperature (90 ° C) conditions.
Widely practical
Method development combination ZORBAX SB-C18
In the ZORBAX SB series, SB-C18 has become an essential star column in the development of liquid phase analysis methods. As shown in the figure below, due to its large steric hindrance and unsealed end features, it can provide selectivity different from conventional C18.
Polarity analysis ZORBAX SB-AQ
ZORBAX SB-AQ can tolerate 100% aqueous phase and improve the retention of polar compounds, playing an important role in polar compound analysis and traditional Chinese medicine characteristic map analysis.
Figure 1 Left: Retention effect of C18 using 2% organic phase, right: SB-AQ using 100% aqueous phase to separate isomers of cefopertan
Figure 2 SB-AQ is used for analysis of Daqingye formula granules (national standard)