TSE shock conditioning system

Startle Response 惊跳反应 The fully computerized TSE Startle Response/PPI test system is designed for accurate and reliable determination of the startle reflex and investigation of sensorimotor gating in rodents, for example in schizophrenia research. In 'PPI' （pre-pulse inhibition） experiments a weak pre-pulse is followed by the startle stimulus inducing a reduced startle response.

TSE shock conditioning systemThe fully computerized TSE startle response/PPI testing system is designed to accurately and reliably detect rodent startle responses and study sensory gating. In the PPI (pre pulse suppression) experiment, a weak pre pulse is followed by a startle stimulus, resulting in a weakened startle response.

Animals are restrained in small cages restricting major movements and placed on species-specific measuring platforms with integrated high-precision sensors in sound-attenuating isolated cabinets. The flexible software package allows the creation of user-defined protocols including complex 'pre-pulse' designs. Reaction time, i.e. response latency, and startle amplitude for each trial are presented in results tables. Graphs allow the performance of several animals to be compared.
TSE shock conditioning systemThe animals are confined to small cages, restricting their primary movement, and placed on species-specific testing platforms integrated with high-precision sensors, in sound shielded cabinets. The flexible software package generates user-defined protocols, including complex "pre pulse" designs. The reaction time, such as reaction latency and the magnitude of each experiment's startle, are shown in the results table. Icons allow for direct comparison of the performance of several animals.
• Pair of high-performance loudspeakers for sine sound and noise generation with up to 130dB startle intensity
A pair of high-performance speakers that generate sinusoidal sound and noise, with an intensity of up to 130dB
• Acoustic pre-pulse and startle stimulus generation with computer-controlled amplitude and frequency setting
Computer controls amplitude and frequency settings to generate sound pre pulses and startle stimuli
• Optional air puff components for tactile startle experiments
Optional blowing component for tactile startle experiments
• Suitable for fear-potentiated and light-enhanced startle trials
Suitable for fear enhanced and light enhanced startle tests

Startle Response/PPI for mice and rats
Used for startle response/PPI in mice and rats