TR1000 is a low wavenumber Raman spectrometer independently developed by Hai Optoelectronics. Adopting a handheld design with a compact structure, the instrument integrates a low wavenumber filter group and a high-sensitivity detector, allowing it to detect Raman spectral signals as low as 20cm-1 and determine the crystal forms of drugs such as glutamic acid, chloramphenicol, and aripiprazole. Combined with professional instrument sampling brackets, it can be placed in the laboratory to study drug crystal forms. At the same time, handheld sampling methods can also be used to collect Raman signals of drugs in synthesis and make preliminary judgments on their crystal forms.