Syntheson RCCS-3D Rotating Microgravity Three Dimensional Cell Culture System3D Cell Culture Gold Standard

Originating from NASA technology, with over 30 years of mature application and 200+high-quality literature verification, unanimously recognized by scientific research and pharmaceutical companies

1、 Product core positioning

Synthecon RCCS‑3D（Rotary Cell Culture System） 是Syntheson R&D and NASA technology conversion in the United StatesofThree dimensional rotating microgravity cell culture systemSpecially designed for simulating the in vivo microenvironment in vitro and constructing highly realistic 3D tissues, it isMature products in the field of 3D cell culture.

2、 Core use (fully covering scientific research/pharmaceutical/clinical needs)

1. Efficient expansion of three-dimensional cellsSupport large-scale high-density cultivation of microcarriers, suitable for fragile/difficult to cultivate cells such as primary cells, stem cells, tumor cells, virus host cells, etc,Fast proliferation, high activity, and strong product secretion.

2. Construction of organoid/tissue modelsCultivate normal tissue, cancer tissue, tumor tissue, and virus infected tissue models,Highly restored physiological and pathological characteristics in the bodyNo dedifferentiation or morphological abnormalities.

3. Application of the entire process of drug developmentHigh throughput drug screening, long-term efficacy evaluation, in vitro toxicology testing, vaccine/biological product preparation,Significantly replacing animal experiments, reducing costs and shortening cycles.

4. Regenerative Medicine and Cell TherapyConstruction of tissue engineering for bone marrow, liver, pancreas, skin, heart, nerves, cartilage, blood vessels, etc., to support in vitro tissue section expansion and repair research.

5. Basic life science researchFrontier topics such as cell matrix interaction, signal transduction, gene regulation, virus host interaction, genetics, and tumor mechanisms.

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3、 Typical usage scenarios (full scene adaptation)

• Universities/research institutesBasic research in cell biology, oncology, virology, and regenerative medicine

• Pharmaceutical companies/CROsNew drug screening, toxicological evaluation, biopharmaceutical/vaccine development

• Hospital/Clinical Laboratory: Organoid drug sensitivity, personalized treatment, tissue engineering repair

• Biological Laboratory: Primary cell/stem cell culture, virus amplification, high-density cell production

• Disease Control/BiosafetyResearch on safe cultivation of highly pathogenic viruses (such as HIV, Ebola, influenza, etc.)

4、 Core advantage (crushing traditional 2D and ordinary 3D cultivation)

1. Technical origin: NASA orthodoxy

• Founded in 1990 by the inventor of NASA's Cell Program,NASA Technology TransferThe orthodox microgravity rotation cultivation technology has been continuously iterated for over 30 years,Extremely mature and stable technology.

2. Cultivation environment: truly simulating the micro weight inside the body

• Three dimensional balance of gravity, centrifugal force, and Coriolis force, cellFree fall suspensionNo stirring, no bubbles, no shear damage,Zero stress, high survival.

• Silicone gas exchange membrane for efficient gas exchange, uniform supply of nutrients/oxygen, cellsThree-dimensional growthReproduce the three-dimensional structure inside the body.

3. Compared to traditional 2D cultivation: Addressing pain points

• Say goodbye to the wall sticking caused by flat surfacesDe differentiation, abnormal gene expression, and loss of function

• Cells maintain physiological characteristics within the body,More suitable for long-term cultivation and functional maintenance.

4. Compared with ordinary dynamic 3D culture: non-invasive and highly differentiated

• No liquid shear force, no physical external force damage,Significant increase in survival rate of fragile cells/primary cells/stem cells

• Addressing endogenous growth deficiency, cultivableEngineering organizationSupporting regenerative medicine and cell therapy.

5. Operation and adaptation: flexible and efficient

• Dual mode of culture disk/column, adjustable speed, suitable for different stages of cell/tissue growth

• Compatible with microcarriers and biological scaffolds, supportingLow cost, large-scale, high-throughputcultivate

5、 Core features of the product (fully matured)

1. Extremely mature technologyNASA origin, 30+years of market validation, stable use by tens of thousands of users, no technical risks

2. A huge amount of literature：200+high-level SCI papers with empirical evidence, including top journals such as Nature, PLOS One, Oncotarget, etc., a complete list of literature is provided for free

3. recognition

• Produced by Syntheson in the United States,3D Cell Culture Gold Standard

• Multiple universities, hospitals, pharmaceutical companies, and research institutions in China have made bulk purchases,Domestic recognition

• Adaptation to cancer, viruses, tissue engineering, drug development, etcNational Key Research Direction

4. cell compatibility

• Primary cells: human keratinocytes, liver cells, bone marrow cells, fibroblasts, etc

• Cell lines: CHO, BHK, various tumor cell lines

• Organizations: liver, spleen, lungs, skin, prostate, etc

• 病毒： HIV、 埃博拉、流感、EB 病毒等高致病病毒

5. Compliance and Service*

• Provide technical support, literature review, after-sales maintenance, one-stop worry free service

6、 Why choose RCCS-3D? (One sentence summary)

NASA+30 years of mature technology+200+high score literature recognitionLet your cells be culturedCloser to the body, more stable, more efficient, and more scientifically persuasiveIt is involved in drug development, tumor research, regenerative medicine, and virology3D cultivation platform！