Pharmaceutical specialized small animal nebulization drug delivery device

Pharmaceutical specialized small animal nebulization drug delivery device (I) Product use

1. Accurately simulate clinical administration routes
This device can directly deliver drugs or modeling agents to animal lungs, highly simulating the real scenario of human inhalation therapy (such as asthma, COPD).

2. Building a reliable disease model
By nebulizing specific inducers, it is possible to ensure that pathogenic factors act uniformly and controllably on the lungs, thereby ensuring the consistency and stability of animal models. Constructing animal models of respiratory diseases (such as asthma, pulmonary fibrosis, and pulmonary infections)

3. Used for the entire process of inhaled new drug development
Pharmacodynamic evaluation: validating the therapeutic efficacy of candidate drugs in disease models.
Pharmacokinetic studies: precise evaluation of drug absorption, distribution, and metabolic characteristics through the lungs.
Toxicological research: Investigating the potential irritation or toxicity of new drugs on the respiratory system to ensure safety.

4. Improve data quality and repeatability
Compared to invasive procedures such as tracheal instillation, nebulized administration can significantly reduce animal stress responses and avoid interference with the immune and endocrine systems caused by stress. Ensuring high reproducibility of the experiment and accuracy of the data, in compliance with animal ethics and scientific standards.


5. Support exploration in cutting-edge fields
This instrument is also a key platform for expanding cutting-edge research in lung gene therapy, nucleic acid drug delivery, and nano targeted formulations, used to evaluate the deposition, penetration, and efficacy of new treatment methods in the lungs.

（2） Developed and produced by Beijing Yuansen Kaide,Pharmaceutical specialized small animal nebulization drug delivery devicePerformance advantages:

① Accurate and controllable aerosol generation：
The dual fluid atomization technology using * can generate highly uniform and stable aerosol particles. MMAD is usually within the range of 1-5 μ m, ensuring that drugs can efficiently deposit in specific respiratory areas of experimental animals (such as alveoli or bronchi) to simulate the inhalation administration process in humans.

② The size of the animal dosing chamber can be customized：
Provide multiple specifications of independent sealed drug delivery chambers, suitable for experimental animals of different body types such as mice, rats, guinea pigs, etc. Transparent materials facilitate real-time observation and enable parallel administration of drugs to multiple animals, ensuring consistency in experimental conditions and greatly improving research efficiency.

③ Easy to operate, safe and efficient
Key parameters such as atomization time and drug delivery gas flow rate can be accurately set. The system is equipped with efficient filters to purify the exhaust gas, effectively preventing the diffusion of drug aerosols in the laboratory environment and ensuring the safety of researchers' operations.
④ Multiple academic institutions have purchased and published multiple high-quality papers
(1) The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine，COMMUNICATIONS BIOLOGY | (2024) 7:181 |，Bronchial epithelial transcriptomics and experimental validation reveal asthma severity[1]related neutrophilc signatures and potential treatments

(2) Lingnan Medical Research Center, Guangzhou University of Traditional Chinese Medicine,Apoptosis，ITGAM‑macrophage modulation as a potential strategy for treating neutrophilic Asthma: insights from bioinformatics analysis and in vivo
experiments



(3) Shanghai Jiao Tong University School of Medicine Affiliated Xinhua Hospital,Dovepress，
Active-Ingredient Screening and Synergistic Action Mechanism of Shegan Mixture for Anti-Asthma Effects Based on Network Pharmacology in a Mouse Model of Asthma



(4) Key Laboratory of Natural Pharmacology, School of Pharmacy, Fujian Medical University,Using the HY-JSE01 small animal nebulization drug delivery device developed and produced by Beijing YSKD BIO-TECHNOLOGY CO., LTD. (YSKD)jet nebulizer (YSKD Biotechnology Co., Ltd., Beijing, China)， A high scoring paper on multifunctional gold nanoclusters for the study of lung tissue distribution of novel anti asthma inhaled antibodies was published in the top journal Analytical Chemistry in Zone 1 of the Chinese Academy of Sciences.






Company Profile
Beijing Yuansen Kaide Biotechnology Co., Ltd. was established in 2013 in Zhongguancun Science Park, Beijing. It is a technology innovation enterprise specializing in the research, production, and sales of life science experimental instruments. Services in toxicology, pharmacology, immunology, biosafety, air pollutants, chemical toxicity identification, preclinical drug development and safety evaluation, respiratory system, environment and health, and other fields.

Yuansen Kaide has technical contact centers in Beijing, China and Pennsylvania, USA, focusing on pre-sales, in sales, and after-sales communication of instruments, always keeping up with the latest developments in the industry. The customer base mainly includes major universities, experimental animal research units, drug development institutions, and third-party companies across the country<a data-cke-saved-name='OLE_LINK1' style='color: rgb(7, 130, 193); background-image: url(' t='F0RD'); ' background-position:='' left='' background-size:='' background-repeat:='' background-attachment:='' background-origin:='' background-clip:='' border:='' 1px='' dotted='' padding-left:='' cursor:='' font-family:='' trebuchet='' font-size:='' name='OLE_LINK1'>CROAnd hospital central laboratories, etc. We are committed to becoming an excellent supplier of experimental instruments and equipment in the industry with high-quality products and excellent services.

Our goal is to prioritize customer service and make the use of scientific research instruments easier and more efficient.