Key points of lactic acid bacteria freeze-drying technology and advantages of biopharmaceutical freeze-drying machine application

Lactic acid bacteria are a type of probiotic，It is a general term for bacteria that can produce a large amount of lactic acid by utilizing fermentable carbohydrates，Widely used in the food industry andbirdsanimal husbandryBecauseLactic acid bacteria are highly thermosensitive substances, TraditionalProcessing method cannot be usedsatisfymodernindustryProduction needs，The current application of biopharmaceutical freeze-drying machine in the freeze-drying processing of lactic acid bacteria involves vacuum freeze-drying of lactic acid bacteria according to the key points of lactic acid bacteria freeze-drying technology. Based on practical experience, biopharmaceutical freeze-drying machine has good application advantages in lactic acid bacteria processing and is currently commonly referred to as lactic acid bacteria freeze-drying machine in the lactic acid bacteria industry.

Freeze drying technology of lactic acid bacteriakey pointIt is to conduct the bacterial suspension in a low-temperature environment below the triple pointlow temperaturefreezeCrystallize into a solid，after thatvacuumEnvironment，Lactic acid bacteriafreezeiceDirectly sublimate into gas to removego.The entire vacuum freeze-drying process requires control over the following key points of freeze-drying technology:
1. Pre freezing temperature and pre rate;

2The temperature control range, heating rate, material temperature control, and vacuum fine adjustment range for a single drying process;

3Analyze the temperature control range, heating rate, vacuum fine adjustment range, material temperature control, and insulation temperature control for drying.

The biopharmaceutical freeze-drying machine has the following advantages in the application of lactic acid bacteria freeze-drying:
1. Lactic acid bacteriaNot exposed to air at low temperatures, losing moisture, can effectively prevent microbial activity and protein denaturation that can cause spoilage, effectively extending the shelf life of lactic acid bacteria.

2. Lactic acid bacteria are dried at low temperatures, and the thermosensitive components and microbial activity in the material are fully protected.

3. Lactic acid bacteriaIt is carried out in a vacuum oxygen deficient state, where some easily oxidizable components in the substance are destroyed and reduced.

4. Lactic acid bacteria are sublimated and dried. After the water sublimates, the lactic acid bacteria remain in the frozen ice shelf, and after drying, they become loose and porous sponge like, with good rehydration properties.

5. Lactic acid bacteria freeze-drying can remove more than 99% of moisture, allowing the dried material to be stored at room temperature for a long time.

The freeze-drying processing of lactic acid bacteria requires mastery of mature freeze-drying technology in order to use biopharmaceutical freeze-drying machines for freeze-drying processing of lactic acid bacteria. The entire technical solution requires training and guidance from technical engineers.