Fluorescence imaging endoscope

Fluorescence imaging endoscopeFIVE2 (ViewnVivo) B30 is a new miniature confocal fluorescence endoscope from Optiscan *, suitable for real-time preclinical in vivo imaging studies of animals, suitable for in vivo and in vitro imaging of small animals.
Fluorescence imaging endoscope hasPoint scanning confocal * * technology. The miniature probe is embedded in a complex mechanical scanner, including a pair of lenses, to focus the laser at the desired precise depth. The laser is transmitted, and the returning light is captured through an optical fiber that moves (scans) across the field of view to capture the entire image. The system controls the speed of fiber scanning and can be adjusted accordingly based on the laser power to provide the best results.
The following figure compares traditional bundled fiber optic technology (left) with Optiscan point scanning technology (right). Image set A displays sample scans at full screen resolution. Image set B represents the focal region (point of interest) of the sample image, while image set C is a scaled view of that focal region. As you can see, traditional bundled fiber optic technology cannot provide clarity and detail anywhere close to point scanning technology.

Specification parameters of fluorescence imaging endoscope
Image resolution:<0.5um horizontal,<4.5um axial
Imaging depth: 0-400um (without moving the probe and animal)
Z-axis step: 3um
Field of view size: 475x475um
Wavelength: 488nm
Probe outer diameter: 4mm
Standard probe: 66mm (hard type, other types available)
Probe cable: 1500mm length
Filter wheel: 12 position hole
Image acquisition: single frame, Z-stacks，ROll-back
Image output: TIFF