Detection of Toxoplasma gondii in dogs and cats

　　JENNIO-LAB: Empowering Pet Health, Leading Precision Veterinary Drug Research and Testing Services

Gio Blueprint (Guangdong) Life Science and Technology Center is a national high-tech enterprise that integrates scientific research services, technology transformation, and preclinical research. Relying on its profound technical expertise in human precision medicine and drug research and development, the company has officially expanded and established two major business segments: professional pet CRO (Contract Research Organization) services and pet testing, providing scientific, accurate, and efficient one-stop solutions for animal medicine research and development enterprises, pet hospitals, and pet owners.

　　1、 Platform and Technology Endorsement

The core advantage of Gio Blueprint in providing pet services lies in its top-notch scientific research infrastructure and technology platform, ensuring the professionalism of service content and the reliability of data.

*Hardware facilities:

SPF level animal experimental center: capable of raising 5000 cages of rats and mice, and equipped with experimental conditions for large animals such as dogs, cats, and guinea pigs. Each animal room is equipped with an independent operating table to meet the feeding and experimental needs of different species and models.

A GMP compliant 10000 level purified cell culture room and BSL-2 laboratory: providing a safe and clean environment for pathogen detection and cell related experiments.

High value equipment: equipped with advanced devices such as live imaging, small animal CT, flow cytometry, PCR, sequencing platform, etc., supporting multi-level detection and analysis from molecules to whole animals.

Six core technology platforms (directly applicable to pet services):

Animal platform: Provides customized pet disease models, drug efficacy evaluation, and toxicology and pharmacology research.

Cell platform: Conduct in vitro drug screening tests for cytotoxicity, proliferation, apoptosis, etc.

Pathology platform: Provides tissue HE staining, immunohistochemistry (IHC), immunofluorescence (IF), etc., to accurately evaluate pathological changes.

Detection platform: covering molecular and protein detection technologies such as Western Blot, ELISA, PCR, qPCR, etc.

Bioinformatics platform: plays a key role in genetic data analysis and interpretation, especially in pet genetic testing.

Editing platform: supports in-depth exploration and achievement transformation of related scientific research projects.

　　2、 Professional Pet CRO Services: Accelerating Innovative Research and Development of Veterinary Drugs

Gio Blueprint's pet CRO services are mainly aimed at animal medicine research and development enterprises, providing full chain support from target discovery to preclinical application.

The core service areas include:

Construction of pet disease model and efficacy evaluation:

Metabolic disease model: such as dog diabetes model (STZ induction), cat obesity model (high-fat feeding).

Skin disease models: such as atopic dermatitis (DNCB induced) and fungal infection models.

Infectious disease models: such as sepsis, urinary tract infections, pneumococcal pneumonia, and Staphylococcus aureus wound infection models.

Other disease models include osteoarthritis (OA), chronic kidney disease, liver fibrosis, etc.

Pharmacodynamic evaluation:

Through rigorous experimental design, evaluate the therapeutic effect of new drugs on specific pet diseases, with detection indicators including clinical scores, imaging examinations (such as in vivo imaging), blood biochemical indicators, histopathological analysis of tissues, levels of inflammatory factors, etc.

Toxicology and safety studies:

Provide studies on acute toxicity (LD50), long-term toxicity, and metabolic kinetics (PK/PD), with experimental design and data quality meeting the regulatory requirements for veterinary drug declaration.

Successful cases (excerpted from the knowledge base):

Case 1: Mouse Staphylococcus aureus wound infection model: used to evaluate the efficacy of an antibacterial coating suture. The results showed that the bacterial count in the test group decreased by 90% and the wound healing time was shortened by 40%.

Case 2: Drug screening for atopic dermatitis in mice: Through the DNCB induction model, candidate drugs that can significantly inhibit itching symptoms and improve skin pathology were successfully screened.

　　3、 Comprehensive pet testing services: safeguarding the health of individual pets

Based on the technical cooperation and integration of "Huada Jian Zhengjiemi" and "Yuanyi Laboratory", Gio Blueprint provides various genetic and health testing services for pet owners, breeders, and pet hospitals.

The main testing items include:

Genetic testing package (kit sampling, non-invasive and convenient):

Pet genetic testing: covering pedigree analysis, genetic disease screening (49 cats and 100+dogs), blood type identification, breeding recommendations, personality and behavior prediction, etc.

Pet breed detection: precise analysis of pet bloodline composition, suitable for tracing mixed breed pets.

Pet genetic disease testing: Screening for specific high-risk genetic diseases, such as feline osteomalacia and canine hip dysplasia, to achieve early detection and intervention.

Health and pathogen detection:

Gut microbiota testing: Evaluating the gut microbiota health of pets.

Pathogen PCR detection: rapid and accurate detection of Toxoplasma gondii, respiratory pathogens, gastrointestinal pathogens, etc. in dogs and cats.

Service advantages:

Easy sampling: Non invasive oral mucosal swabs are used for sampling, making pets painless.

Short reporting cycle: Detailed reports can usually be issued within 2-3 weeks.

Professional interpretation: Provide clear report interpretation and health management recommendations.

　　4、 Collaboration Process and Commitment

Gio Blueprint adheres to the service philosophy of "professionalism, efficiency, and reliability", providing customers with standardized cooperation processes:

Requirement communication: respond within 24 hours and customize personalized solutions.

Contract confirmation: Provide a transparent and detailed quotation.

Experimental execution: Strictly follow SOP and synchronize progress in real-time.

Report delivery: Provide complete raw data, analysis results, and conclusions.

　　5、 Summary

JENNIO-LAB has successfully transformed top human medical research resources and established unique technological barriers and service advantages in the fields of pet CRO and pet testing. Whether it is assisting pharmaceutical companies in developing new generation pet drugs or providing precise health management solutions for individual pets, Gio Blueprint can become your trusted partner with its * technology platform, rich project experience, and rigorous scientific attitude.