Cell suspension culture on glass microcarriers in microreactors

Anaerobic fermentation bioreactor is a device designed for the development of vaccines, recombinant proteins, monoclonal antibodies, and other biological products, as well as for small-scale and pilot scale testing, clinical sample production, and commercial production. It meets the requirements of clean and sterile production, stable equipment performance, automation, and compliance (data integrity, audit tracking) for clinical samples and drug production.

　　Jimway-be ® Lab series reactor

　　Anaerobic fermentation bioreactorIt is oriented towardsvaccines、recombinant protein、monoclonal antibodyWaiting for biological products,a small test、Pilot development、Clinical sample production and commercial productionThe equipment meets the characteristics and requirements of cleanliness, sterility, stable equipment performance, automation, and compliance (data integrity, audit tracking) required for clinical sample and drug production.

　　*Cultivation dish volume: 0.35L/0.75L/1.5L/3L/5L/7L/10L/15L

　　*Culture dish material: high borosilicate glass that is resistant to high temperature, acid and alkali, and corrosion

　　*Stainless steel material: SS316L stainless steel

　　*Transmission mode: servo electrode&magnetic coupling drive

　　*Temperature control method: Bottom ceramic electric heating/electric heating blanket

　　*Interface: Four hole feeding, sampling, harvesting, flame inoculation, surface ventilation, bottom ventilation, cooling water

Exhaust condenser, sensor port (PH/DO/liquid level/temperature), spare port

Function:

　　*Suitable for the cultivation, fermentation, and expression of prokaryotic/eukaryotic cells

　　*Fully automatic pH/DO/TE/tank pressure control

　　*Accurate feeding control (error ± 0.1g)

　　*PID&Ladder Control Strategy (Feeding, Mixing Speed, Temperature, Ventilation, etc.)

Advantage:

　　*Concise interface: Mastering the operation in one hour, achieving twice the result with half the effort

　　*Unmanned: can be accessed and operated remotely, achieving unmanned operation

　　*Formula function: One click distribution of formulas, reducing personnel operational errors and improving quality

　　*Data analysis: enables comparison of multiple batches of data, and can also be integrated with Doe&PAT for in-depth multivariate analysis to optimize process data

　　*Data sharing: Based on VPN for web publishing, it enables monitoring and historical curve viewing on mobile devices (Android, IOS, Windows) while ensuring data and device security

Features:

　　*Cleanliness: Following ASME BPE, in line with international standards, with sterile design, the surface of the tank is smooth and not prone to residual dirt, making it easy to clean, disinfect, and maintain.

　　*Sealing: Adopting excellent sealing technology to ensure that the tank body does not leak under high pressure, ensuring the safety and stability of the experiment

　　*Stability: Supports continuous cell culture for 30 days * 24 hours

　　*Intelligence: Based on ISA-88 self-control architecture and ISA-95 network architecture, supporting batch control of MES and other software to achieve path management

　　*Compliance: A complete set of GEP/GMP documents from RA to RTM to ensure compliance