COSMOSIL 3C18-EB chromatographic column

NegotiableUpdate on 05/15

Model

Nature of the Manufacturer: Producers

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Place of Origin

Online Consult

Overview

The COSMOSIL 3C18-EB chromatographic column uses capping technology, which improves the peak shape and separation of alkaline compounds.

Product Details

Product Description

Even after using traditional capping techniques to cap C18 chromatography columns, there are still many residual silanol groups on the surface of silica gel, which can form ionic bonds with alkaline compounds. The resulting tailing peak will make precise analysis of alkaline compounds difficult, especially trace analysis.COSMOSIL 3C18-EB chromatographic columnThe use of capping technology has resulted in superior peak shapes and separation of alkaline compounds.

Separation performance of alkaline compounds
Suitable for drug analysis

Comparison of Separation Performance of Alkaline Compounds

COSMOSIL 3C18-EB碱性化合物的分离性能对比

reproducibility

If an insufficiently capped C18 chromatographic column is used to analyze alkaline compounds, you will spend a lot of time adjusting the mobile phase. You may need to:

Three or more organic phases and buffer salts

Ionic reagents or additives

Buffer salts with different pH values

In addition, complex flow is a test of relative reproducibility.
Due to the use of a new capping technology, COSMOSIL 3C-18 only requires a simple mobile phase to achieve excellent peak shapes and separation.

Usage information

chromatographic column	3μm 3C₁₈-EB
Inner diameter (mm)	1.0	2.0	3.0	4.6
Column length (mm)	ALL	ALL	ALL	10	50-250
Factory solvent	Acetonitrile/water=60/40
flushing method	Method for removing buffer, salt, and acid from the chromatographic column: Rinse with a mobile phase free of buffer, salt, and acid for 10-15 minutes. Example: When the mobile phase is methanol/phosphate buffer (20mmol/L)=50/50, rinse with methanol/water=50/50 The method of flushing the attached substances in the chromatographic column and the solution when the baseline is unstable When the sample is not protein, rinse with methanol or *. When the sample is protein, use 0.1%C2HF3O2Rinse with 50-70% acetonitrile/water

Shenzhen Dongfang Lantai Technology is a high-tech company specializing in the import of laboratory analytical instruments and equipment such as gas chromatography, liquid chromatography, electronic balance, electrochemical instruments, general instruments and equipment, chromatography columns, reagents, standards, etc. At the beginning of its establishment, the company insisted on focusing on the analysis industry and was committed to introducing domestic and foreign analytical instruments to a wide range of domestic users. Currently, the company's users have spread to scientific research institutions, colleges and universities, hospitals, chemical industry, food, medicine, agriculture, mining, power, metallurgy and other industries and units.