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Shanghai Qifa Experimental Reagent Co., Ltd

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    Shanghai Qifa Experimental Reagent Co., Ltd., No. 6619 Chuansha Road, Chuansha Town, Pudong, Shanghai

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17 β - estradiol sustained-release tablets

NegotiableUpdate on 05/06
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Overview

17 β - estradiol sustained-release tablets are a representative sex hormone. It can be prepared from ovaries, placenta, etc. and can be detected in follicular fluid, placenta, and pregnant horse urine. After entering the uterine epithelial cells, it forms a complex with sex hormone receptors and enters the nucleus, thereby promoting the synthesis of new proteins and causing cell proliferation. In addition, it can affect the vaginal secretions of immature or ovariectomy rats or mice, presenting a microscopic image composed of keratinocytes, and is therefore also used for biological experiments.

Product Details

🔍 Basic Features

Item number: SE-121, NE-121

●英文名: 17β-ESTRADIOL

Chinese name: 17 β - estradiol sustained-release tablets

Specification: Common doses are 0.18mg, 0.36mg, 0.72mg/tablet; 25 tablets, 50 tablets, 100 tablets, 200 tablets/bottle, supporting customized needs.

Brand: Innovrsch

● CAS number: 50-28-2

Molecular formula: C ₁₈ H ₂₄ O ₂

Molecular weight: 272.38

● Release cycle: Provides three release durations of 21 days, 60 days, and 90 days, achieving stable drug release through subcutaneous implantation.

● Pill characteristics: With a diameter of about 3.0mm, it uses a bioabsorbable matrix and contains inert components such as cellulose, without biological toxicity.

Application areas: mainly used for animal experiments, including:

-Models of estrogen deficiency related diseases (such as osteoporosis and cardiovascular disease);

-Research on the reproductive system (such as simulating postmenopausal status);

-Research on neuroprotection and metabolic regulation.

● Storage and use

-Storage conditions: Low temperature storage is required, with a shelf life of 1 year.

-Implantation method: Subcutaneous implantation (such as in areas of relaxed skin on the neck or back) is performed using a specialized puncture needle.

● Precautions

-For scientific research purposes only, not for clinical treatment;

-It is necessary to follow animal experimental ethics and regularly monitor physiological indicators.


📝 Product Details

SE-12117 β - estradiol sustained-release tabletsIt is a high-purity, low endotoxin research grade reagent with the following core parameters:

-Chemical essence: Steroid compound, molecular formula C ₁₈ H ₂₄ O ₂, molecular weight 272.38 g/mol, CAS number 50-28-2;

-Physical properties: White to off white crystalline powder, easily soluble in organic solvents such as ethanol and acetone, slightly soluble in water;

-Purity certification: tested by HPLC (high-performance liquid chromatography), purity ≥ 99.5% (COA report attached);

-Impurity control: endotoxin ≤ 0.25 EU/mg (applicable to cell/animal experiments), heavy metal residue<10 ppm;

-Packaging specifications: We offer various sizes including 0.18mg, 0.36mg, 0.72mg, 1.7mg, etc., and support customized needs;

-Application scenarios: cell culture (estrogen receptor positive cell lines), animal model construction (such as ovariectomized rats), in vitro hormone activity detection, drug target screening, etc.


✨ core advantage

one ️⃣ High purity, low interference: A purity of over 99.5% far exceeds the industry standard (most competitors have a purity of 85% -95%), greatly reducing the interference of impurities on experimental results (such as cytotoxicity and non-specific binding), especially suitable for experiments with high sensitivity requirements (such as qPCR, Western Blot).

two ️⃣ Full process quality control: From raw material synthesis to finished product packaging, through 12 quality inspection checkpoints (including HPLC, LC-MS, sterility testing, etc.), detailed COA (Certificate of Analysis) is provided for each batch, with traceable data and more reliable experimental results.

three ️⃣ Strong adaptability: Not only does it support conventional solvent dissolution (such as DMSO, ethanol), but it can also provide customized sterile solutions (concentration 1mM-100mM) according to needs, which can be directly used for cell experiments, eliminating the tedious steps of self preparation.

four ️⃣ Worry free after-sales service: provide a professional technical support team to answer questions about experimental design, storage conditions, etc; If there is a quality issue with the received product, we will respond with a return or exchange within 72 hours.


❓ Purchase Questions&Answers

Q1:17 β - estradiol sustained-release tabletsWhat is included in the purity testing report (COA)?

A: COA includes HPLC purity spectra (area normalization method), LC-MS molecular weight validation, endotoxin detection results, heavy metal residue data (lead, mercury, arsenic, etc.), and production batch information to ensure traceability at every step.

Q2: If sterile solution is required for the experiment, can you customize it?

A: Okay! We support aseptic filling services (0.22 μ m membrane filtration) and offer commonly used concentration options ranging from 1mM-100mM. Please note your requirements when placing an order.

Q3: What should be noted for long-term storage?

A: It is recommended to store the packaged solution in the dark at -20 ℃ (to avoid repeated freezing and thawing). The dissolved solution should be refrigerated at 4 ℃ and used up within one month (refer to the instructions for details).

Q4: Is it suitable for in vivo animal experiments?

A: The endotoxin content of SE-121 is ≤ 0.25 EU/mg (much lower than the requirement of ≤ 5 EU/mg for in vivo experiments), and the impurity content is strictly controlled. It can be used for subcutaneous/intraperitoneal injection or gavage experiments in model animals such as rats and mice (specific dosage needs to be referred to in the literature).

Q5: Can small batch purchases (such as 0.18mg) be shipped?

A: Okay! We support a minimum order quantity of 0.18mg, with regular logistics (SF/JD) shipping within 48 hours. Remote areas can be negotiated.

Q6: What are the advantages compared to other brands of 17 β - estradiol?

A: In addition to high purity and strict quality control, we also provide a free "experimental protocol reference package" (including cell culture concentration recommendations, animal model dosage, etc.) to help beginners quickly get started.

Q7: Will it degrade during transportation?

A: The product is transported in an insulated box and ice packs (with additional dry ice added in summer) to ensure a temperature of ≤ -15 ℃ throughout the entire process. After testing and transportation, there is no significant change in purity (a transportation stability report can be provided).

Q8: How long is the shelf life?

A: The unopened powder has a shelf life of 2 years (below 25 ℃), and it is recommended to use up the dissolved solution within 1 month (subject to COA labeling).


For more product information, please contact our regional agent in China: Shanghai Qifa Experimental Reagent Co., Ltd

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(Note: The content of this article is based on brand public information and industry standard information, and the specific information is subject to the brand information document.)


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