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Vicoto (Beijing) Technology Co., Ltd
High performance mass spectrometry imaging system
NegotiableUpdate on 05/06
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Overview
AFADESI-MSI is a novel atmospheric open ionization technique that does not require radioactive isotopes or fluorescent labeling, and can intuitively reflect the in situ metabolic information of target molecules or unknown compound molecules in samples (animal tissues, plant tissues, materials, microorganisms, etc.). Sensitivity can reach PG level, covering 1500 metabolites such as polyamines, amino acids, carnitines, nucleosides, nucleotides, organic acids, carbohydrates, bile acids, lipids, and other metabolites.
Product Details
Product Brief:
1. Open ion source, easy to install and disassemble.
2. Ionization technology: Desorption spray ionization technology.
3. Ion transport technology: Airflow assisted technology, flow rate 10-50L/min.
4. Ion transport distance: ≥ 50cm.
5. The minimum sampling step for the XY axis is ≤ 20 μ m.
6. High definition camera that automatically recognizes the position of the sample.
7. High throughput imaging module: capable of continuously scanning 8 standard glass slides.
8. Whole animal imaging module: imaging area of 150mmx100mm.
9. Porous Plate Rapid Screening Module: It can accommodate porous plates with 96 holes, 384 holes, 1536 holes, and other specifications.
10. Applicable sample types: animal tissue, plant tissue, materials, microorganisms, etc.
Application fields:
1. Pharmacology and toxicology of new drugs, such as spatial distribution, in vivo effects, and molecular mechanisms of drugs
2. Research on molecular mechanism of disease: such as Parkinson's disease, cerebral ischemia, depression, sleep disorder, diabetes, cardiovascular disease, etc
3. Molecular pathological diagnosis of tumors, research on drug resistance and precision medication, biomarker screening, etc
4. Tumor metabolism and tumor immunity, such as tumor metabolic microenvironment and tumor immune escape, etc
5. Reproductive development, such as spatial metabolism regulation and metabolic phenotype during seed, embryo, and organ development processes
6. Environmental toxicology research: spatial distribution and molecular mechanisms of toxicity of environmental pollutants in animals and plants
7. Research on the spatial distribution of active ingredients in medicinal plants, as well as the spatial distribution of primary and secondary metabolites during plant growth and development
8. Research on gene regulation mechanisms: changes in metabolites after gene knockout, understanding the precise relationship between genes and metabolites, etc
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