Ultra high performance liquid chromatography

ACQUITYUPLCH-ClassPLUSUltra high performance liquid chromatography

It is a high-performance quaternary liquid chromatography system designed specifically to improve laboratory efficiency and analytical quality. It is a method conversion tool with low diffusion detection capability, supporting HPLC and UPLC methods, which can significantly improve separation and sensitivity. Through Auto BlendPlus technology and a flexible solvent management system, users can easily optimize mobile phase conditions and accelerate the method development process. In addition, the system is compatible with multiple detectors, providing a comprehensive solution for the characterization of complex samples.

ACQUITYUPLCH-ClassPLUSUltra high performance liquid chromatography

Features and advantages

1. The quaternary solvent manager (QSM) has the flexibility to mix multiple solvents and can mix four solvents in any combination or ratio. By adding an integrated solvent selection valve, the number of solvent types can be increased to nine, thereby achieving higher flexibility. The automatic solvent compression function allows you to run any solvent in any combination while ensuring accuracy and precision.

2. Utilize direct injection to achieve high-precision injection. The circulation needle design ensures the accuracy of needle sealing under high pressure. The injection volume range is 0.1 μ L to 1mL. By setting the method settings, ultra-low residue can be achieved to ensure compatibility with sensitive mass spectrometers.

3. Accurately control the temperature of the entire chromatographic column. 1-6 chromatography columns can be configured, each of which can be loaded into an independent temperature control zone with active preheating function, with a temperature range of 4-90 ° C.

4. Low diffusion detection capability. The ACQUITYUPLCH Class system is a quaternary LC system on the market equipped with multiple optimized detectors that exhibit true UPLC performance. The narrowest UPLC peak can be obtained with the smallest diffusion volume and optimized electronic components and optical paths, resulting in sensitivity and reproducibility for precise quantification.

5. Using AutoBlendPlus technology, the liquid is directly taken from the reagent bottle of pure solvent or concentrated reserve solution, and the mobile phase is automatically prepared according to specific pH values and ionic strengths, greatly reducing the experimental preparation time. This technology is compatible with reverse phase chromatography, IEX, and SEC, making routine analysis easier to manage and execute, and streamlining method development and stability testing. Even small changes in pH and ionic strength can be tested without the need for manual preparation of each individual buffer.

6. Intelligent gradient starting point, which can easily adjust system volume differences when converting methods from another LC system without changing the method gradient table.

7. The supported software includes Empower, Masslynx, UNIFI, and multiple third-party software packages.